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Journal of Clinical and Translational Science
Scopus
ISSN 2059-8661 · Cambridge University Press · 5.423 artikel di indeks
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Artikel Jurnal Teks lengkap
On the prior use of high-fidelity simulation to improve clinical trial development and implementation
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Artikel Jurnal Teks lengkap
Bioinformatics identification and experimental validation of hub genes associated with narcolepsy type 1
Abstract Introduction: Narcolepsy type 1 (NT1) is a chronic neurological disorder with a genetic predisposition, yet its precise molecular pathogenesis remains unclear. Despite increasing recognition of its clinical and genetic basis, the precise molecular mechanisms remain unclear. This study…
Juga tersedia di: DOAJ
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Artikel Jurnal
Who bears the brunt? Geographic, racial and ethnic disparities in mortality trends of inflammatory bowel disorders in the United States
Abstract Background: Inflammatory bowel disease (IBD), encompassing ulcerative colitis (UC) and Crohn’s disease (CD), presents increasing global health burdens. Despite advancements in therapy, disparities in mortality trends across demographic and geographic lines persist in the United States…
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Artikel Jurnal
An open-source application for self-service, Health Insurance and Portability Accountability Act-compliant geocoding
Abstract Objective: DeGAUSS is a privacy-preserving application that ingests addresses and generates output that includes latitude, longitude, census tract, deprivation index and drive times to major hospitals. The application uses a complex command line interface and a container management…
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Artikel Jurnal
A method to enable clinical and translational research teams with custom real-world data from electronic health record systems
Abstract Introduction: Custom transformations of real-world data (RWD) from electronic health record (EHR) systems are necessary to define study variables describing health and disease statuses differently among physicians in multiple specialties and basic scientists from a variety of disciplines…
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Artikel Jurnal
Optimizing the key information section of informed consent documents in biomedical research: A multi-phased study using large language models
Abstract Introduction: Informed consent is a cornerstone of ethical research, but the lack of widely accepted standards for the key information (KI) section in informed consent documents (ICDs) creates challenges in institutional review board (IRB) reviews and participant comprehension. This study…
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Artikel Jurnal
Fidelity of intervention delivery in psychosocial and behavioral programs (FIPP): A modified Delphi study and final guideline
Abstract Introduction: Fidelity – ensuring interventions are implemented as intended – is a key focus in implementation science. Despite its benefits in research and practice, data on the fidelity of implementation are often overlooked, measured inconsistently, or underreported. In 2024, we…
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Artikel Jurnal
Costs and cost-effectiveness of a culturally adapted diabetes self-management and education program for Marshallese adults
Abstract Background: Culturally adapted diabetes self-management education (DSME) programs are effective in improving glycemic control and diabetes outcomes among minority populations, but data on program costs and cost-effectiveness are limited. This study aimed to assess the cost and…
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Artikel Jurnal
A validation study of mentees’ views of mentors’ cultural diversity awareness behaviors (CDA race/ethnicity behaviors scale)
Abstract Introduction: Mentorship is a key focus area of efforts to promote a robust biomedical workforce. A growing body of research suggests that mentors’ cultural diversity awareness is an important factor in effective mentoring that can support mentees’ academic and professional outcomes. Less…
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Artikel Jurnal
Patient perspective of Hesitancies and strategies to increase cancer clinical trial participation
Abstract Introduction: Strategies to improve accrual and reduce barriers to cancer clinical trials participation are critical for the advancement and implementation of new treatments and processes to improve cancer patient outcomes. While researchers have identified several barriers to accrual from…
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Artikel Jurnal
Dental, Oral and Craniofacial Tissue Regeneration Consortium (DOCTRC): An infrastructure for accelerating regenerative therapies from discovery to clinical impact
Translating scientific discoveries in tissue engineering and regenerative medicine (TE/RM) into clinically adopted therapies is hindered by fragmented development pipelines, regulatory and manufacturing challenges, and limited funding. Despite substantial investment by the U.S. National Institutes…
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Artikel Jurnal
Using a participation monitoring database to enhance recruitment in a rare cancer population
Abstract Introduction: Recruitment for rare disease studies is challenging due to small eligible populations. Traditional clinical research management systems often lack tools to track recruitment contacts prior to enrollment. The NET-PRO study, focused on neuroendocrine tumors (NETs), implemented…
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Artikel Jurnal
Art as a multiplier of science communication
Clinical and translational science faces persistent challenges in public trust, effective communication, and siloed knowledge structures. Addressing these issues requires innovative educational and engagement strategies. We present an artist-in-residency program immersed into an undergraduate…
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