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Scopus
ISSN 2075-1729 · MDPI AG · 11.980 artikel di indeks
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Terrisphaera alpina gen. nov., sp. nov., a Cellulolytic Planctomycete Representing the First Described Soil-Inhabiting Member of the Class Phycisphaerae
A novel planctomycete, strain T20PH1T, was isolated from alpine meadow soil collected at an altitude of 1800 m in the North Caucasus Mountains, Russia. Phylogenomic analysis placed it within the family Tepidisphaeraceae of the class Phycisphaerae. The closest relatives based on 16S rRNA gene…
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The Evolving Landscape of Anti-Clonal Therapy in Newly Diagnosed Systemic Light-Chain (AL) Amyloidosis: Evidence- and Time-Based Comparison with Multiple Myeloma
Light-chain (AL) amyloidosis is a rare and incurable disease, classified under the category of plasma cell neoplasms and other diseases with paraproteins in the 5th Edition of the World Health Organization classification of lymphoid tumors. This entity shares some similarities with multiple myeloma…
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“Protective” Imazalil vs Its Negative Effects on Immune System Cells—Neutrophils
Neutrophils are the most numerous population of peripheral blood leukocytes and play a key role in innate immunity, participating in antibacterial, antifungal, antiviral, and antitumor responses. Their activity can be modulated by endogenous and exogenous factors, including pesticides, among which…
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Fitzpatrick Skin Phototype Is Independently Associated with Differential Short-Term Cutaneous Reactivity Following Standardized Topical Provocation in Humans
Background: Human cutaneous reactivity exhibits marked inter-individual variability, yet the contribution of constitutional pigmentation traits to short-term skin responses remains incompletely characterized. Fitzpatrick skin phototype reflects stable differences in pigmentation-related traits and…
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Robot-Assisted Radical Prostatectomy After Rezūm: A Case Report and Literature Review
Minimally invasive surgical therapies (MISTs), such as Rezūm™ Water Vapor Therapy, are emerging treatment options for benign prostatic obstruction (BPO). When prostate cancer is subsequently diagnosed, radical prostatectomy may still be indicated. However, evidence regarding intraoperative…
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Pharmacological and Medicinal Properties of the South American Medicinal Plant Bowdichia virgilioides Kunth and Its Bioactive Products
Bowdichia virgilioides Kunth is a tree largely present in South America, notably in the Cerrado savannah. The species is known for the quality of its dense and resistant wood, used in construction and furnishing. B. virgilioides is also a medicinal plant used, from leaves to roots, for the…
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Preoperative Parameters Associated with Vitrectomy Outcomes in Myopic Traction Maculopathy Without a Full-Thickness Macular Hole
Pathologic myopia has become a major global cause of blindness, making timely surgical management for myopic traction maculopathy (MTM) increasingly important. This study aimed to identify prognostic factors associated with functional and anatomical outcomes following surgery for MTM and to…
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Development and Clinical Validation of an Artificial Intelligence-Based Automated Visual Acuity Testing System
Background: To develop and validate an automated visual acuity (VA) testing system integrating artificial intelligence (AI)–driven speech and image recognition technologies, enabling self-administered, clinic-based VA assessment; Methods: The system incorporated a fine-tuned Whisper…
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Optimization of Cultivation Substrate Formula and Key Physical Parameters for Domestication of Floccularia luteovirens by Response Surface Methodology
Floccularia luteovirens is an edible and medicinal fungus with great development value on the Qinghai–Tibet Plateau, but its artificial domestication and cultivation are limited by the lack of systematic research on cultivation substrate formulas and key parameters. This study adopted the technical…
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Comparison of Scrotal Orchiopexy Versus Traditional Inguinal Orchiopexy for Palpable Undescended and Retractile Testis in Children: Insights from a Greek Surgical Center
Introduction/Purpose: Congenital cryptorchidism and retractile testis represent the most commonly presented abnormalities of the male genitourinary system. Orchiopexy is the surgical treatment for both conditions and can be performed either via the conventional two-incision surgical approach or via…
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Diabetes Mellitus as a Risk Factor for Severe Disease and Mortality Among Patients with Melioidosis: A Systematic Review and Meta-Analysis
Background: Melioidosis is a potentially fatal infectious disease caused by Burkholderia pseudomallei and is highly prevalent in tropical regions. Diabetes mellitus (DM) is the most common comorbidity among patients with melioidosis and is a well-established risk factor for acquiring the infection…
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Selective Androgen Receptor Modulators in Women: What Do We Know, and What Is Still Missing
Androgens and androgen receptor (AR) signaling influence many aspects of female physiology, including reproduction, musculoskeletal health, metabolism, and neurological regulation, yet are less studied than in males. Selective androgen receptor modulators (SARMs) were developed to provide…
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Deciphering the Boron Toxicity Tolerance Mechanisms of Triticum dicoccoides via RNA-Sequencing
Boron (B) toxicity is one of the major abiotic stresses limiting wheat productivity in arid and semi-arid regions of the world. Thus, it is important to understand the molecular basis of tolerance in boron-tolerant wheat genetic resources for effective breeding. Wild emmer wheat is a valuable…
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Diagnostic Value of Mean Platelet Volume and Hematological Inflammatory Ratios in Brucellosis: A Case–Control Study
Brucellosis diagnosis remains challenging in resource-limited endemic settings. This retrospective case–control study evaluated the diagnostic utility of mean platelet volume (MPV) and hematological inflammatory ratios in brucellosis. Fifty patients with confirmed brucellosis and 50 age-matched…
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Medial Pterygoid Muscles Penetration by Tubero-Pterygoid Implants: Clinical, Anatomical and Statistical Insights Regarding Temporo-Mandibular Disorders (TMDs)
Background: The medial pterygoid muscle (MPM) is frequently implicated in pain and dysfunction in patients with temporomandibular disorders (TMDs), owing to its functional complexity, susceptibility to overload, and rich neuromuscular control. Paradoxically, in patients rehabilitated with…
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Coronary Artery Spasm in Patients with Type 2 Diabetes Mellitus
Cardiovascular disease and diabetes mellitus have now reached pandemic proportions, and their association has become very common. Some patients with coronary artery disease and diabetes remain symptomatic, with chest pain present despite the implementation of evidence-based medical treatment and…
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Effect of Dystocia Duration on the Placental Health in Canines
The study aimed to determine whether placental lesions differ according to the duration of dystocia. Forty-seven placentas were obtained from 18 bitches that underwent emergency cesarean sections. For descriptive purposes, the cases were classified into four groups based on the duration of…
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The Role of Granulocyte Colony-Stimulating Factor in Endometrial Preparation for Embryo Implantation in In Vitro Fertilization
Granulocyte colony-stimulating factor (G-CSF) has been suggested as a supplementary approach for endometrial preparation in IVF. Clinical results continue to be inconsistent. This narrative review synthesises molecular and clinical information to elucidate the function of G-CSF in modifying…
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Comparative Effectiveness and Safety of Denosumab Versus Bisphosphonates in Elderly Patients with Cancer Bone Metastases: A Target Trial Emulation Study
Objective: Bone-modifying agents (BMA) are central to the prevention of skeletal-related events (SREs) in patients with cancer bone metastases, yet evidence guiding agent selection in very old patients remains limited. This study aimed to compare the effectiveness and safety of Denosumab versus…
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Artikel Jurnal Teks lengkap
The Association Between the Triglyceride–Glucose Index and the Risk of Diabetic Kidney Disease in Patients with Type 2 Diabetes Mellitus: A Cross-Sectional Study
This study aimed to evaluate the association between the triglyceride–glucose index (TyG) and the risk of diabetic kidney disease (DKD) in patients with type 2 diabetes mellitus. Methods: This study included 1347 patients with type 2 diabetes who attended the endocrinology clinic at Jordan…
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