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Medical Sciences
Scopus
ISSN 2076-3271 · MDPI AG · 1.573 artikel di indeks
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Artikel Jurnal Teks lengkap
From Sentiment to Signal: Narrative–Physiology Discordance as a Testable Target for Artificial Intelligence in Critical Care
Intensive care units generate dense physiological, laboratory, imaging, microbiological and treatment data, yet much of the clinical reasoning that drives decisions is recorded only in free text. Over the past decade, clinical sentiment analysis has repeatedly shown that the affective tone of…
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Challenges of Effective Clinical Teaching Organization at Public Medical Universities in Poland: A Delphi Method Study
Background/Objectives: Clinical teaching as a form of interpersonal education organized in a real clinical setting is very dynamic and sensitive to many factors that may influence its effectiveness. To strengthen clinical education organization, responsible bodies should meet emerging challenges…
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Global, Regional, and Country Incidence of Peritoneal Dialysis-Associated Peritonitis in the Contemporary Peritoneal Dialysis Practice: A Systematic Review and Meta-Analysis
Background/Objectives: Since peritoneal dialysis (PD) has been used in nephrology practice for several decades, contemporary evidence on global, regional, and country incidence rates of PD-associated peritonitis has not been comprehensively synthesized. We performed a systematic review and…
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Audiometric Monitoring and Its Determinants in Patients Undergoing Chemoradiotherapy for Head and Neck Cancer
Background and Objectives: Audiometric monitoring is recommended for patients receiving ototoxic (chemo)radiotherapy for head and neck cancer (HNC), yet real-world uptake is poorly characterized and potentially inequitable. We quantified the uptake and timing of audiometric testing and examined…
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Effects of Liraglutide and Semaglutide on Cardiometabolic Dysregulation and Oxidative Stress in an Experimental Model of Metabolic Syndrome
Background/Objectives: Metabolic syndrome (MetS) increases susceptibility to myocardial ischemia/reperfusion (I/R) injury through metabolic disturbance, hypertension, and oxidative stress. This study aimed to compare the effects of liraglutide and semaglutide on post-ischemic cardiac function…
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Relationship Between Flow and Absolute Humidity During Active Humidification for High-Flow Therapy: A Bench Study
Active humidification of medical gases is a fundamental component of high-flow oxygen therapy (HFOT). Given the high gas flow rates employed, it remains unclear whether the theoretically expected relationship between flow rate, temperature, and absolute humidity is maintained under clinical…
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Neonatal Outcomes Associated with Maternal-Factor-Related Diagnoses: Real-World Evidence from a National Inpatient Database (2010–2025)
Background/Objectives: Maternal conditions and lifestyle exposures strongly influence neonatal morbidity, but population-level longitudinal data from Central and Eastern Europe remain limited. This nationwide study evaluated 16-year trends (2010–2025) in neonatal hospital episodes with…
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Comparison of Direct 3D Scans and Plaster Casts in Digital Ankle–Foot Orthosis Workflows
Background: Digital ankle–foot orthosis (AFO) workflows depend on accurate lower limb geometry acquisition. Direct 3D scanning on the lower limb may reduce plaster use, but its geometrical agreement with orthotist plaster casting remains insufficiently investigated. Objective: This study compared…
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Safety and Efficacy of Thermal Ablation for Cervical Lymph Node Metastasis from Papillary Thyroid Carcinoma: A Systematic Review of Available Evidence
Background/Objectives: Cervical lymph node metastasis and nodal recurrence remain clinically significant problems in papillary thyroid carcinoma (PTC). Thermal ablation techniques, including laser ablation (LA), radiofrequency ablation (RFA), and microwave ablation (MWA), have increasingly been…
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Artificial Intelligence and the Ethical Foundations of Cardiothoracic Surgery: Evidence, Accountability, and the Limits of Delegated Judgment
Artificial intelligence (AI) is moving rapidly from retrospective prediction and image analysis into treatment selection, operative planning, intraoperative guidance, and postoperative prognostication in cardiothoracic surgery. This transition raises an ethical problem that cannot be resolved by…
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Modeling Hemorrhagic Shock in Male SD Rats by Fixed Volume Blood Withdrawal Followed by Partial Resuscitation and Long-Term Outcome Assessment
Background/Objectives: Hemorrhagic shock (HS) is one of the leading causes of disability and mortality in intensive care units. Animal modeling of HS is important for preclinical research to elucidate mechanisms and develop treatments. Methods: Adult male SD rats were divided into three groups…
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Pleomorphism in Soft Tissue Sarcomas: Molecular Characteristics and Clinical Features
Pleomorphism in cells encompasses a variety of morphological features, such as heterogeneity in the size and shape of cells and nuclei, irregularity of the nuclear membrane, hyperchromasia, and peculiarities of cell organelles. Pleomorphism in mammalian cells is associated with genetically unstable…
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Translating Population-Based Epidemiology into Clinical Recognition of Coronary Artery Spasm: Prevalence, Incidence, and Geographic-Seasonal Variation in Taiwan
Background: Coronary artery spasm (CAS) is a reversible cause of myocardial ischemia, infarction, and sudden cardiac death. Often under-recognized and influenced by ethnicity, geography, and environment, CAS requires population-level data. This study examined nationwide CAS epidemiology in Taiwan…
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Combined Molecular Hydrogen and Vitamin C Treatment in Irradiated Normal and Cancer Cell Models: An Exploratory In Vitro Study and Case Reports
Background: Radiation therapy is widely used to treat cancer but frequently causes normal tissue toxicities that compromise patients’ quality of life, highlighting the need for strategies that protect healthy tissue without reducing antitumor efficacy. Here, we investigated whether a…
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Genomic Characterization of RTK-RAS Pathway Alterations in Juvenile Myelomonocytic Leukemia Through Whole-Exome Sequencing
Background/Objectives: Juvenile myelomonocytic leukemia (JMML) is a rare and very aggressive pediatric myelodysplastic/myeloproliferative neoplasm with molecular heterogeneity and constitutive activation of the RAS signaling pathway. The aim of this study was to identify the mutational landscape…
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Early Detection of Glottic Cancer Through Machine Learning and Acoustic Voice Analysis: A Systematic Review
Purpose: Early detection of glottic cancer is essential for better outcomes, but current diagnostic methods remain largely invasive, highlighting the need for reliable non-invasive alternatives. Acoustic voice signals offer a non-invasive screening input, but their clinical value depends on whether…
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Is Milk Elimination Enough? A Systematic Review and Meta-Analysis of One-Food Elimination Diet in Eosinophilic Esophagitis
Background/Objectives: Dietary management, particularly through food elimination, has emerged as an effective therapeutic strategy for eosinophilic esophagitis (EoE). In this context, a one-food elimination diet (1-FED) targeting cow’s milk has been proposed as a targeted and less restrictive…
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The Possible Hematological Cost of Metabolic Success: Do Incretin-Based Therapies Silently Trigger Anemia?
Diabetes mellitus and obesity represent a growing global health burden with high morbidity and mortality. In the last several years, novel incretin-based therapies have been developed, and their use has risen dramatically. Beyond their proven metabolic, glycemic, cardiovascular, renal, and many…
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Platelet-Rich Plasma in Recurrent Pregnancy Loss: Toward a Precision Medicine Framework for Biologically Guided Patient Selection
Recurrent pregnancy loss (RPL), a multifactorial condition in reproductive medicine, affects approximately 1–3% of couples. Increasing evidence implicates endometrial dysfunction, immune dysregulation, impaired angiogenesis, and oxidative stress (OS) in its pathophysiology, highlighting the need…
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Update on the Physiopathology of Keratoconus
Keratoconus (KC) is a progressive corneal ectasia characterized by stromal thinning, steepening, and biomechanical instability. Although historically considered primarily a structural disorder, current evidence supports a multifactorial pathogenesis involving complex interactions among…
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