10.707 hasil
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Brain Sciences
Scopus
ISSN 2076-3425 · MDPI AG · 10.707 artikel di indeks
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Artikel Jurnal Teks lengkap
Toward Standardized Protocols: Determining Optimal Stimulation Volumes for 5 Hz Repetitive Peripheral Magnetic Stimulation (rPMS) of the Tibial Nerve—A Controlled Exploratory Study
Background: Repetitive peripheral magnetic stimulation (rPMS) has emerged as a promising non-invasive treatment modality for reducing muscle hypertonus and spasticity. However, standardized protocols regarding stimulation parameters, particularly the number of stimuli required to achieve…
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Detecting Dementia Using Lexical Analysis: Terry Pratchett’s Discworld Tells a More Personal Story
Background/Objectives: Dementia, characterised by cognitive decline, significantly impacts language abilities. While the risk of dementia increases with age, it often manifests years before clinical diagnosis. Identifying early warning signs is crucial for timely intervention. Previous research has…
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Adult-Onset Diffuse Midline Glioma, H3K27-Altered: A Genomics-Guided, Individualized, Multimodal Treatment Approach
Background: H3K27-altered diffuse midline glioma (DMG) is a highly aggressive central nervous system malignancy with limited therapeutic options and poor prognosis. Precision medicine strategies that integrate molecular profiling with individualized treatment selection represent a critical avenue…
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Global and Local Processing of Letters and Faces in Children and Adolescents with Typical and Atypical Development
Background/Objectives: this paper investigates the local vs. global visual processing preference in typically developing (TD) children, youth with Down syndrome (DS), and youth with Williams syndrome (WS). In particular, the global precedence effect (GPE) and the global interference effect (GI)…
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SleepMFormer: An Efficient Attention Framework with Contrastive Learning for Single-Channel EEG Sleep Staging
Background/Objectives: Sleep stage classification is crucial for assessing sleep quality and diagnosing related disorders. Electroencephalography (EEG) is currently recognized as a primary method for sleep stage classification. High-performance automatic sleep staging methods based on EEG leverage…
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A Prefrontal Neuromodulation Route for Post-Traumatic Olfactory Dysfunction: A Perspective Supported by Recovery During Left-DLPFC rTMS
Post-traumatic olfactory dysfunction (PTOD) is a common and often persistent sequela of mild traumatic brain injury (mTBI), with limited evidence-based treatment options. We propose that high-frequency rTMS applied to the left dorsolateral prefrontal cortex (DLPFC) may support olfactory recovery…
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Switching from Oral Cholinesterase Inhibitors to a Transdermal Donepezil Patch Attenuated Gastrointestinal Symptoms and Allowed Treatment Continuation in Three Patients with Alzheimer’s Disease in Clinical Settings
Background: Cholinesterase inhibitors (ChEIs) are commonly prescribed for the treatment of Alzheimer’s disease (AD) and achieve long-term benefits for cognition and survival in real-world settings. However, the discontinuation rate is high due to their side effects, with gastrointestinal (GI)…
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Etiology, Symptoms, and Treatment of Epilepsy: Advances and Perspectives
Epilepsy is a chronic neurologic disorder characterized by recurrent and spontaneous seizures (Figure 1) [...]
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Mindfulness-Based Intervention for Treatment of Anxiety Disorders During the Postpartum Period: A 4-Week Proof-of-Concept Randomized Controlled Trial Protocol
Background/Objectives: Anxiety disorders (ADs) affect up to 20% of mothers in the postpartum period, characterized by psychological symptoms (e.g., emotion dysregulation; ER) and physical symptoms (e.g., disrupted bodily awareness). Although Cognitive Behavioural Therapy effectively reduces anxiety…
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Calpain-2 Regulates Kinesin and Dynein Dysfunction in Neurotoxin-Induced Motoneuron Injury
Background/Objectives: Neurodegenerative diseases are driven by multiple interconnected pathological mechanisms involving both intrinsic and extrinsic molecular and cellular processes. Efficient bidirectional intracellular transport is essential for neuronal survival and function, enabling the…
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The Contribution of Ethnicity to the Association of MTHFR Variants C677T and A1298C with Autism Spectrum Disorder: A Meta-Analysis
Background: Common polymorphisms in the MTHFR gene, C677T and A1298C, have been associated with increased risk for psychiatric neurodevelopmental disorders, including autism spectrum disorder (ASD). However, studies provide conflicting evidence for the strength of the association with ASD based on…
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Relationships Among Functional Status, Global Self-Reported Categorical Measure of Activity Level, Health-Related Quality of Life and Psychological State in Patients with Parkinson’s Disease in Greece
Background/Objectives: Parkinson’s disease is the second most common neurodegenerative disorder, affecting patients’ daily lives in multiple domains, including functional status, health-related quality of life, and psychological well-being. This study examined the relationship between self-reported…
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Alterations in Multidimensional Functional Connectivity Architecture in Preschool Children with Autism Spectrum Disorder
Background: Autism Spectrum Disorder (ASD) is a type of neurodevelopmental disorder, and its exact causes are currently unknown. Neuroimaging research suggests that its clinical features are closely linked to alterations in brain functional network connectivity, yet the specific patterns and…
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Neurobiophilia
Despite unprecedented disconnection from nature and increased urbanisation, the brain still shows an affinity for nature. However, biophilia lacks a neuroscience foundation despite growing evidence of how the brain changes in response to the contrasting influences of urban and natural environments…
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Efficient and Accurate Epilepsy Seizure Prediction and Detection Based on Multi-Teacher Knowledge Distillation RGF-Model
Background: Epileptic seizures are unpredictable, and while existing deep learning models achieve high accuracy, their deployment on wearable devices is constrained by high computational costs and latency. To address this, this work proposes the RGF-Model, a lightweight network that unifies seizure…
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Increase in Comforting Behavior (Allogrooming) During Social Interaction in Male Mice Deficient for the Slp Gene of Complement Component C4
Background: Oxytocin (OT) is a nonapeptide hormone produced in the hypothalamus, released into the brain and peripheral circulation, and plays a key role in social behavior. Recent studies indicate that complement component C4a is an OT-binding protein, which modulates plasma OT concentrations in…
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Achievement Motivation, Meaning in Life, and Well-Being Among Video Game Players
Background/Objectives: The present study aimed to examine the associations among achievement motivation, meaning in life, and well-being among video game players and to investigate differences between players with approach- and avoidance-oriented motivations. Methods: The sample consisted of 296…
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TSCL-LwF: A Cross-Subject Emotion Recognition Model via Multi-Scale CNN and Incremental Learning Strategy
Background/Objectives: Wearable affective human–computer interaction increasingly relies on sparse-channel EEG signals to ensure comfort and practicality in real-life scenarios. However, the limited information provided by sparse-channel EEG, together with pronounced inter-subject variability…
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Is Migraine a Risk Factor for Non-Arteritic Anterior Ischemic Optic Neuropathy? Insights from a National Case–Control Study
Purpose: While migraine is linked to increased cerebrovascular risk, its association with non-arteritic anterior ischemic optic neuropathy (NAION) remains underexplored. Methods: We conducted a retrospective case–control study using population-based electronic medical records. NAION patients were…
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Extracting Weight of Evidence from p-Value via Bayesian Approach to Activation Likelihood Estimation Meta-Analysis
Background: p-values are ubiquitous in scientific research, yet they fundamentally fail to quantify the strength of evidence for or against competing hypotheses. This limitation is particularly problematic in neuroimaging meta-analyses, where researchers need to assess how strongly the available…
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