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Rambam Maimonides Medical Journal
Scopus
ISSN 2076-9172 · Rambam Health Care Campus · 532 artikel di indeks
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Artikel Jurnal
Methodological Considerations in Assessing Mental Health Burden Among Caregivers of Special Needs Children
To the Editor: I read with interest the paper by Priya et al. and appreciate their study examining the mental health status among parental caregivers of children with special needs in Puducherry. The authors addressed an important and understudied population in the Indian caregiver context. Their…
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Response to Letter to the Editor: Prospective Validation of PaDd—A Roadmap
To the Editor: We thank Dr Vijayasimha and colleagues for their thoughtful analysis of our work and their proposal for prospective validation of the Padua × D-dimer (PaDd) score. Their roadmap provides a rigorous framework that addresses critical gaps in our single-center retrospective design. We…
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A PaDd-informed, Assay-calibrated Diagnostic Pathway for Suspected Pulmonary Embolism in Older Adults: From Signal to Strategy
To the Editor: We commend Cohen et al. for introducing a prag-matic composite—Padua score × D-dimer (PaDd)—designed to refine pulmonary embolism (PE) exclusion in adults aged ≥65 years, a population often characterized by multimorbidity, physiological heterogeneity, and atypical presentations…
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Bringing Rehabilitation Home: A Policy and Practice Perspective on COPD Management
To the Editor: We thank Thakur and Bhatia for their insightful letter, “Home-based Pulmonary Rehabilitation in COPD: Bridging Evidence and Practice for Compre-hensive Patient-centered Care,” and for their gracious recognition of our study, “From Breathless-ness to Better Living: Transforming COPD…
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The Toothache of Rabbi Judah ha-Nasi
The Talmud describes several illnesses attributed to Rabbi Judah ha-Nasi, one of the foremost leaders of the Jewish people after the destruction of the Second Temple, and the compiler of the canonical Mishnah. Among these conditions, Tzafedina of the oral cavity is mentioned, characterized by…
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Incretin Analogues for Weight Reduction in Non-Diabetic Obese: A Review of Liraglutide, Semaglutide, and Tirzepatide Beyond Glycemic Control
Obesity is a complex, multifactorial disease that contributes to a broad range of cardiometabolic, reproductive, and psychological disorders. Representing a major global health challenge, obesity can be addressed by lifestyle modifications such as reduced calorie intake, physical activity, adequate…
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Immune Checkpoint Inhibitor-induced Hepatitis, an Emerging Issue in Precision Cancer Therapy Era: A Narrative Literature Review
Immunotherapy using immune checkpoint inhibitor (ICI) has been increasingly used in the oncology treatment field. Although ICIs could help suppress cancer and improve survival rates, it could also lead to certain adverse events, including immune-mediated liver injury caused by ICIs (ILICI). The…
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Artikel Jurnal
The Halakhic Heartbeat at the Edge of Life: Navigating Maternal Brain Death and Fetal Life
This paper presents a halakhic-ethical analysis of a 2025 case involving A.S., a brain-dead pregnant woman who was maintained on somatic support to enable fetal maturation and delivery. The case raises profound questions at the intersection of Jewish law and contemporary medical practice…
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Ampullary Neuroendocrine Tumors: Multicenter Experience and Emerging Perspectives on Endoscopic Treatment
Background: Ampullary neuroendocrine tumors (NETs) are extremely rare, representing 0.3%–1% of gastrointestinal NETs and less than 2% of periampullary cancers. Due to their rarity, there is limited data on their natural history, management, and outcomes. Current European Neuroendocrine Tumor…
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Formal Education in Leadership and Management for the Practicing Clinician
As clinicians progress in their careers, they are often tasked with projects and responsibilities that require additional education, knowledge, and training in leadership and management. In the past, they were expected to pick up these skills along the way; current expectations, however, are…
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The Expanding Role of the Urologist in Metastatic Prostate Cancer: From Biopsy to Surgical Interventions
The evolving landscape of metastatic prostate cancer (mPCa) necessitates a redefinition of the urologist’s role, extending beyond diagnosis to active participation in therapeutic and surgical management. This review outlines evidence-based approaches to biopsy and surgical interventions across the…
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Response to Savel’s “Reconsidering the Scope and Structural Integration of Leadership Education for Clinicians”
To the Editor, I read with great interest the narrative review by Savel (2025) examining formal education in leader-ship and management for practicing clinicians, particularly those working in critical care settings. While the review clearly describes the educational opportunities available…
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Anatomy of Antisemitism in Health Professions Education and Practice: A Narrative Review
There has been an international resurgence in antisemitism in healthcare education and practice since October 7, 2023, prominently affecting the United States (US), United Kingdom (UK), Canada, and Australia. In the US, federal investigations by the US Department of Justice, and the Congressional…
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Physician-assigned Diagnosis Versus Questionnaire-based Measures in Individuals with Nociceptive, Neuropathic, and Nociplastic Pain: A Mechanism-based Characterization of Chronic Pain Patients
Background: The International Association for the Study of Pain (IASP) has defined three mechanisms for chronic pain: nociceptive, neuropathic, and nociplastic. Accurate differentiation between these mechanisms is essential for treatment selection but remains challenging due to symptom overlap and…
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Artikel Jurnal
Insomnia as an Independent Behavioral Correlate of Estimated Type 2 Diabetes Risk: Evidence from Three Validated Risk Assessment Scales
Background: Sleep disturbances, particularly insomnia, are increasingly recognized as behavioral determinants of type 2 diabetes (T2DM). However, their contribution to validated diabetes risk scores beyond traditional sociodemographic and lifestyle factors remains insufficiently explored…
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Artikel Jurnal
IgG4-Related Mastitis: An Underrecognized Diagnosis in Breast Core Biopsies
We address the critical diagnostic challenge of IgG4-related mastitis (IgG4-RM), a rare tumor-like condition that may represent an isolated breast involvement or be the initial manifestation of systemic IgG4-related disease. IgG4-RM presents a significant diagnostic pitfall in the context of core…
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Jewish Contributions to Plastic and Reconstructive Surgery
While individual Jewish plastic surgeons have been recognized in the literature for their groundbreaking achievements, a comprehensive review of their collective contributions to plastic surgery is lacking. The goal of this review is to document and highlight the major advancements made by Jewish…
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Mifepristone: Reflections on its Early Clinical Development for Medical Abortion
Mifepristone (RU-486), the first clinically effective progesterone antagonist, was initially identified as having antiglucocorticoid activity. Although early interest focused on its role as a glucocorticoid receptor antagonist, recognition of its antiprogesterone effects led to studies of its role…
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Deprescribing: Reducing Harm, Enhancing Care
Introduction: Polypharmacy carries the potential for increased risk and severity of adverse reactions. Deprescribing may reduce adverse events and possibly hospitalizations, although evidence on hard outcomes such as mortality is mixed. As the medication experts responsible for the close monitoring…
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Artikel Jurnal
Comparison of Red Blood Cell Features in Israeli Circassians: The Possible Effect of Residential Altitude
Background: The Circassian community in Israel represents a unique, endogamous population residing in two villages in the northern region of Israel: Kfar Kama (209 meters above sea level [m.a.s.l.]) and Rihaniya (674 m.a.s.l.). Objectives: This study sought to investigate whether the small…