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Biology
Scopus
ISSN 2079-7737 · MDPI AG · 10.271 artikel di indeks
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Mitochondrial Phylogenomics of Tenthredinidae (Hymenoptera: Tenthredinoidea) Supports the Monophyly of Eriocampinae stat. nov.
Tenthredinidae (Hymenoptera: Tenthredinoidea), the most species-rich sawfly family, features a controversial subfamily classification, particularly regarding Eriocampa Hartig, 1837, Conaspidia Konow, 1898, and their relatives. In this study, we sequenced and characterized 15 complete mitochondrial…
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Biogeochemical Element Cycling in Plant–Soil Systems: Implications for Ecosystem Dynamics and Services
Biogeochemical element cycling in plant–soil systems is fundamental for ecosystem dynamics and services [...]
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Retinal Astrocytes: Key Coordinators of Developmental Angiogenesis and Neurovascular Homeostasis in Health and Disease
Retinal astrocytes reside mainly in the nerve fiber layer and are central to shaping retinal vessels and maintaining neurovascular balance. Derived from the optic nerve head, they spread across the inner retina to form a meshwork that both supports and instructs the emerging superficial vascular…
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Durable Management of Plant Viruses: Insights into Host Resistance and Tolerance Mechanisms
Plant viruses cause substantial yield and quality losses worldwide, and their rapid evolution can erode deployed host resistance. This review synthesizes current knowledge of antiviral resistance and tolerance mechanisms, using barley yellow dwarf virus (BYDV) in cereals as an illustrative case…
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Therapeutically Induced Modulation of Collagen I-to-III Ratio Three Weeks After Rabbit Achilles Tendon Full Transection
During tendon healing, collagen III expression precedes that of collagen I. The collagen I-to-III ratio at a certain time point post-laceration serves as an indicator of the healing status. Consequently, it is crucial to understand how different therapeutic approaches to support tendon healing…
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Suppressing Endothelial–Mesenchymal Transition Through the Histone Deacetylase 1/GATA Binding Protein 4 Pathway: The Mechanism of Protocatechuic Acid Against Myocardial Fibrosis Revealed by an Integrated Study
Background: Myocardial fibrosis, a central pathological process leading to heart failure, lacks specific mechanism-based therapies. Although the anti-inflammatory activity of the natural compound protocatechuic acid is recognized, its direct anti-fibrotic mechanism, particularly concerning the…
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Maternal Embryonic Leucine Zipper Kinase (MELK) in Cancer: Biological Functions, Therapeutic Potential, and Controversies
The Maternal Embryonic Leucine Zipper Kinase (MELK) gene is a member of the Snf1/AMPK serine/threonine kinase family. MELK has recently attracted considerable interest in cancer biology due to its aberrant overexpression in various malignancies, including glioma, breast, lung, colorectal, gastric…
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Biotechnological Potential of Algerian Saffron Floral Residues: Recycling Phytochemicals with Antimicrobial Activity
This study investigates the phytochemical profile, antioxidant capacity, and antimicrobial potential of Crocus sativus L. (saffron) tepal extracts obtained via different solvent systems. Here, a biochemical screening was performed using spectrophotometry and HPLC-DAD, while molecular docking…
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Neurobiological Convergence in SPDs and ADHD: Insights from a Narrative Review
The sensory system plays a critical role in development, as it enables the processing and integration of internal and external stimuli. Dysfunctions in this system lead to sensory processing disorders (SPDs), which affect approximately 5–13% of children aged 4–6 years, impacting not only sensory…
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Comprehensive Metabolomic–Transcriptomic Analysis of the Regulatory Effects of Armillaria mellea Source Differences on Secondary Metabolism in Gastrodia elata
Armillaria mellea (A. mellea) serves as a crucial nutritional source for Gastrodia elata (GE) growth, and its origin directly influences the GE quality and yield. This study analyzed GE symbiotic with A. mellea from different sources using metabolomics and transcriptomics. Results demonstrated that…
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Deleterious Mutations in the Mitogenomes of Cetacean Populations
Cetaceans are artiodactyls adapted to live in the marine environment, and this group includes whales, dolphins, and porpoises. Although mitochondrial nucleotide diversity has been reported separately for many cetacean groups, the proportion of deleterious mutations in these populations is unknown…
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Applying a Method to Estimate the Breeding and Non-Breeding Population Fractions of the Globally Threatened Red-Spectacled Amazon
Population size estimates are essential for investigating numerous aspects of the ecology, evolution, and conservation of wildlife. However, the life cycles of many species include cryptic life stages that are difficult to detect or sample, such as the non-breeding fractions typical of many bird…
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Multi-Omics Analysis Reveals the Adaptive Responses of Lycoris aurea to Arid Stress
Understanding how plants respond to water limitation is increasingly important under accelerating climate change. Lycoris aurea, a widely distributed ornamental and medicinal bulbous plant, frequently inhabits environments with fluctuating soil moisture, yet its molecular drought-response…
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Response Strategies of Giant Panda, Red Panda, and Forest Musk Deer to Human Disturbance in Sichuan Liziping National Nature Reserve
The persistent expansion in the intensity and scope of human disturbance has become a key driver of global biodiversity loss, affecting wildlife behavior and population stability across multiple dimensions. As a characteristic symbiotic assemblage in the subalpine forest ecosystems of Sichuan, the…
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The Genetic Landscape of Androgenetic Alopecia: Current Knowledge and Future Perspectives
Androgenetic alopecia (AGA) is the most common cause of progressive hair thinning in adults and has traditionally been viewed as an androgen-driven inherited condition. Genomic research now demonstrates that AGA is a complex polygenic disorder involving multiple biological pathways, including…
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Medicinal Plants for Overcoming Drug Resistance in Cervical Cancer
Drug resistance remains a significant challenge in cancer therapy, accounting for most relapses and contributing substantially to cancer-related mortality worldwide. Several molecular processes are linked to the development of resistance to anticancer drugs, with the most studied mechanisms…
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Physiological and Transcriptomic Responses of the Freshwater Hydrozoan Craspedacusta sowerbii to Acute Antibiotic and Cadmium Exposure
Chemical contaminants are increasingly detected in freshwater environments, yet the physiological and molecular responses of many non-model freshwater invertebrates to acute chemical stress remain poorly understood. In this study, we investigated the physiological and transcriptomic responses of…
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Characteristics and Phylogenetic Considerations of the Newly Sequenced Mitochondrial Genome of Teratoscincus scincus (Gekkota: Sphaerodactylidae)
Sphaerodactylidae play a crucial role in ecosystems, possessing significant ecological, scientific, and conservation value. They contribute to pest control and the maintenance of ecological balance, and also provide abundant materials for research in evolutionary biology and biodiversity. To refine…
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Establishment and Polymorphism Analysis of SNP Markers in the Gynogenic Blunt Snout Bream
The blunt snout bream (Megalobrama amblycephala, BSB) is a freshwater economic fish with Chinese characteristics, and its genetic characteristics have unique value for studying fish evolution. The gynogenetic blunt snout bream (GBSB) obtained through distant hybridization between cross-order…
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Force-Dependent Presence of Senescent Cells Expressing Vascular Endothelial Growth Factor During Orthodontic Tooth Movement
Orthodontic force magnitude influences angiogenesis during orthodontic tooth movement (OTM); however, the role of senescent cells remains largely unclear. This study investigated the localization of senescent cells and their expression of vascular endothelial growth factor (VEGF) during…
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