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The Egyptian Journal of Histology (2026)
Scopus
ISSN 2090-2417 · Egyptian Society of Histology and Cytology · 953 artikel di indeks
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Artikel Jurnal
THE POSSIBLE PROTECTIVE EFFECT OF BERBERINE ON MONOSODIUM GLUTAMATE INDUCED LIVER TOXICITY IN ADULT MALE ALBINO RATS
Objective: A known dietary additive called monosodium glutamate (MSG) has been associated to inflammation, oxidative stress, apoptosis, and liver injury. A naturally occurring isoquinoline alkaloid, berberine has strong hepatoprotective, anti-inflammatory, and antioxidant qualities. Aim: Through…
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Artikel Jurnal
Histological, Immunohistochemical, and Biochemical Study of the Effect of Semaglutide on the Cardiac Muscle of Obese and Non-Obese Albino Rat: The Role of Adiponectin, Tumor Necrosis Factor Alpha (TNF-α), and Caspase-3
Abstract Introduction: Semaglutide (SEM) is a novel glucagon-like peptide-1 receptor agonist that can efficiently treat type-2 diabetes and obesity. Although it has a very important role in the cardiovascular system, it may be associated with various adverse effects. Aim: to explore the role of…
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Artikel Jurnal
IMPACT OF CITALOPRAM AND DEANXIT ON PROTAMINE-1 GENE EXPRESSION, BIOCHEMICAL PARAMETERS, AND HISTOPATHOLOGICAL ALTERATIONS IN HEPATIC AND TESTICULAR TISSUES OF ALBINO RATS
Background: Antidepressants are routinely used to treat depression and anxiety disorders; however, significant concerns have arisen regarding their potential adverse effects on reproductive and liver function. This study aimed to evaluate the effects of citalopram and Deanxit on protamine-1 gene…
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Artikel Jurnal
Histological and Biochemical Study on The Protective Effect of Green Coffee Bean Extract on Induced Retinal Ischemia in Albino Rats
Introduction: Retinal ischemia is a critical condition linked to various ocular diseases, including glaucoma and diabetic retinopathy, often leading to visual impairment. The retina's high metabolic rate makes it highly susceptible to ischemic injury, which involves energy failure, oxidative…
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Artikel Jurnal
Neuroprotective Effects of Intranasal Chitosan-Coated Lacosamide Liposomes in an AlCl₃/D-Galactose-Induced Rat Model of Alzheimer's Disease: Histological, Immunohistochemical, and Ultrastructural Evaluation of the Hippocampus
Objective: Alzheimer's disease (AD) therapy is often hindered by poor blood-brain barrier (BBB) permeability. This study evaluated the neuroprotective potential of intranasally administered chitosan-coated lacosamide nanoparticles (LCM-NPs) in a rat model of AlCl₃/D-galactose-induced AD. Methods…
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Possible Therapeutic Role of Curcumin versus Mesalazine in Acetic Acid-induced Ulcerative Colitis in Adult Female Albino Rat: A Comparative Histological, Immunohistochemical and Biochemical Study
Background: Inflammatory bowel disease (IBD) results from a dysregulated immune response to gut microbiota and includes ulcerative colitis (UC) and Crohn’s disease. Experimental UC can be induced in rats using acetic acid (AA). Mesalazine [5-aminosalicylic acid (5-ASA)] is widely used for treatment…
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Ashwagandha Nanogel Effects Against Imiquimod-Induced Psoriasis in Rats: A Histopathological Study
Introduction : The use of nanogels is a promising and innovative approach to drug delivery for psoriasis, a complex autoimmune disease influenced by both environmental and genetic factors. Ashwagandha is one of the most popular Ayurvedic herbs in India. It has recently received attention for its…
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Artikel Jurnal
The neuroprotective effect of resveratrol loaded lipid-core nanocapsules and cerebrolysin on midbrain of parkinsonism albino rats model: histological study
Background: Parkinson's disease treatments remain symptomatic, failing to halt dopaminergic degeneration. This study evaluated the neuroprotective potential of Cerebrolysin (CBL), free resveratrol (RES), and resveratrol-loaded lipid nanocapsules (RSV-LNCs) against haloperidol-induced Parkinsonism…
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Artikel Jurnal
The Emerging Role of Aloe Vera and Hyaluronic Acid Nanoparticles in Tissue Regeneration: A New Horizon for Advanced Therapeutics in Dentistry
Background: Current evidence is insufficient to substantiate the purported regenerative and proliferative effects of Aloe vera (AV) and Hyaluronic acid (HA) nanocomposite formulations in gingival therapies within the field of dentistry. Objective: To elucidate the proliferative effects of AV-AA@AG…
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Neoadjuvant Chemotherapy in Luminal A Breast Carcinoma: Histopathological Evidence of Limited Impact
Introduction. Breast cancer is the most frequently diagnosed malignancy among women worldwide, including in Saudi Arabia. Aim of work: This retrospective study evaluated the histopathological alterations in luminal A breast carcinomas following neoadjuvant chemotherapy (NAC). Material and Methods…
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An immunohistochemistry investigation of cyclin E2 expression in breast cancer with clinicopathological relationships in the Najaf governorate of Iraq
Breast cancer is a rapidly growing tumor that develops in benign breast cells and is one of the most common causes of neoplasm-related death globally. The dysregulation of cyclin E2, a regulatory protein necessary for the cell cycle, especially during the transition from S phase to G1 phase, was…
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Artikel Jurnal
L-Carnitine Supplements Ameliorate the Energy Drinks-Induced Testicular Oxidative Stress and Ultrastructural Alterations in Adult Male Wistar Albino Rats
Energy drinks (EDs) are widely consumed beverages associated with various adverse health effects, including potential reproductive assault. This study aimed to investigate the deleterious effects of ED consumption on testicular structure and function, and to evaluate the protective role of…
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Artikel Jurnal
Effect of Topical Sildenafil Citrate versus Conventional Minoxidil in Treatment of Androgenic Induced Alopecia in the Adult Male Albino Rats
Background: Androgenic alopecia (AGA) is a widespread form of hair loss, progressively impairs hair follicle structure and function, affecting both genders. AGA can significantly impact psychological wellbeing and quality of life. Although topical minoxidil remains a standard treatment, its…
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Artikel Jurnal
Comparative study between the ameliorative effect of Agmatine and metformin on lung fibrosis complicating diabetes in rats
Abstract: Background and Aims: Lung fibrosis is a serious problem complicating diabetes mellitus. Metformin improves glycemic control and reduces inflammatory markers. Agmatine enhances glucose homeostasis with insulinotropic, anti-inflammatory, and antioxidant effects. Both agents attenuate…
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Artikel Jurnal
Ashwagandha Root Extract Alleviates the Aging Related structural and Functional Kidney Changes in Rats
Background: The aging process extremely affects both kidneys. Different morphological and functional changes are linked to renal aging. Objectives: Our study aimed to assess the ameliorative effects of ashwagandha root extract on the aging-related renal alterations in adult rats. Materials and…
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Artikel Jurnal
Histological, Immunohistochemical, Biochemical, and Ultrastructural Evaluation of the Protective Effect of Semaglutide and Green Coffee Bean Extract in Diabetes‑Induced Testicular Injury in Adult Albino Rats
Background: Diabetes mellitus is a prevalent metabolous condition that negatively impairs male reproductive function through oxidative stress, inflammation, apoptosis, and structural damage to testicular tissue. Streptozotocin induced diabetes is associated with impaired spermatogenesis, hormonal…
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Artikel Jurnal
Histopathological and Immunohistochemical Assessment of Timolol in Enhancing Cutaneous Burn Wound Healing in Rabbits
This study has been performed in order to show the therapeutic action of timolol in burn injuries and skin wounds because this drug has previously shown a variety of benefits in accelerating skin healing. The experiment was applied to a rabbit model in which full-thickness thermal burns were…
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Artikel Jurnal
Comparative Histological Study on the Effect of Bone Marrow-Derived Mesenchymal Stem Cells versus their Exosomes on Induced Cardiomyopathy in Male Albino Rats
Introduction: Myocardial infarction (MI) is among the more serious cardiovascular diseases (CVDs). Isoproterenol (ISO) mimics cardiac muscle damage by increasing heart activity. Treatment using bone marrow-derived mesenchymal stem cells (BM-MSCs) and their exosomes has been studied due to their…
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Artikel Jurnal
The Potential Ameliorative Effect of MicroRNA-21-enriched Extracellular Vesicles Derived from Bone Marrow Mesenchymal Stem Cells on Isoproterenol-induced Myocardial Infarction in Adult Rats: A Histological, Immunohistochemical and Biochemical Study
Introduction: Myocardial infarction (MI) is a leading cause of death worldwide. New effective therapies are urgently needed because cardiomyocytes have a capacity to regenerate. Bone marrow‐mesenchymal stem cell‐derived extracellular vesicles (BM-MSC-EVs) have emerged as promising mediators of…
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Artikel Jurnal
VITAMIN C AND VITAMIN K2 ATTENUATE BIOCHEMICAL AND HISTOPATHOLOGICAL INJURY IN L-ORNITHINE-INDUCED ACUTE PANCREATITIS IN RATS
Overview: Acute pancreatitis (AP) considered as a crucial malady causing injury to the acinar cells in pancreas due to oxidative stress and cytokine release. Vitamin C is a well-established antioxidant shows a protective effect in experimental pancreatic damage model, but few studies tackled the…