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Alexandria Journal of Medicine
ISSN 2090-5068 · Wolters Kluwer Medknow Publications · 383 artikel di indeks
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Artikel Jurnal
Prevalence and predictors of adequate health literacy among in-school adolescents in Nigeria: a cross-sectional study
Introduction Health literacy is the set of personal qualities and societal assets required for individuals and communities to access, comprehend, evaluate, and use knowledge and resources to make decisions regarding their health. There is a dearth of information on the prevalence of health literacy…
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Artikel Jurnal
Molecular signatures of metastatic triple-negative breast cancer as prognostic markers
Background Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer with limited therapeutic options. Molecular alterations in PIK3CA mutations and cyclin D1 (CCND1) may serve as prognostic biomarkers; however, their role in metastatic TNBC (mTNBC), particularly in Egyptian…
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Artikel Jurnal
Serum interleukin-17 as a marker of disease activity and tissue damage in systemic lupus erythematosus patients
Context Systemic lupus erythematosus (SLE) is a multisystem disease characterized by immune system dysfunction due to both genetic susceptibility and environmental factors. Several disease activities scoring systems are present for example, Systemic Lupus Erythematosus Disease Activity Index…
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Artikel Jurnal
Tailgut cysts: two case reports and a comprehensive literature review
Tailgut cysts (or hamartomas) are rare congenital anomalies, typically occurring in females due to incomplete regression of the embryonic tailgut. While often asymptomatic, they can transform malignantly if untreated. Preoperative MRI plays a crucial role in diagnosis and determining the approach…
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Artikel Jurnal
The association between hypertriglyceridemic-waist phenotype and incidence of coronavirus disease 2019 in a large adult population of central Iran
Background: There is ongoing controversy regarding the role of the hypertriglyceridemic-waist phenotype in coronavirus disease 2019 (COVID-19) morbidity and mortality outcomes. This study aimed to evaluate the association between HTGW phenotypes and the incidence of COVID-19. Patients and methods…
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Artikel Jurnal
Ultrasonic optic nerve sheath diameter in correlation with neurological complications of severe preeclampsia
Background: Preeclampsia is a systemic disorder characterized by new-onset hypertension and proteinuria after 20 weeks of pregnancy. Neurological involvement is one of the most serious complications, as it can lead to significant morbidity or even death if not recognized and treated properly on…
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Comparison between simultaneous integrated boost and sequential boost intensity-modulated radiation therapy technique in treating head and neck cancer patients
Purpose: This study evaluated acute toxicity, tumor response, and disease-free survival (DFS) between simultaneous integrated boost intensity-modulated radiation therapy (SIB-IMRT) and sequential boost IMRT (SEQ-IMRT). Patients and methods: The research comprised 50 patients, split into two groups…
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Comparative study of endoscopic and microscopic stapedotomy in the surgical management of otosclerosis
Background Otosclerosis is a primary osteodystrophic disorder of the otic capsule that leads to stapes fixation and conductive hearing loss. Both microscopic and endoscopic stapedotomy improve hearing outcomes, yet comparative data on intraoperative visibility and postoperative complications remain…
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Bone mineral density in children with inflammatory bowel disease
Background Inflammatory bowel disease (IBD) is a chronic condition characterized by immune-mediated inflammation of the gastrointestinal tract, which significantly impacts bone growth and bone mineral density (BMD). Objective This study aims to study BMD in pediatric patients with IBD. Patients and…
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Artikel Jurnal
Parental knowledge, perceptions, and acceptance toward human papillomavirus vaccine in Al-Baha City, Saudi Arabia: a cross-sectional study
Background Human papillomavirus (HPV) is a common sexually transmitted infection linked to cervical cancer, which ranks as the sixth or higher prevalent cancer among women aged 15–44 in Saudi Arabia. Although an effective HPV vaccine exists, uptake remains low. Objective To assess parental…
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Artikel Jurnal
Rapid molecular detection of respiratory pathogens causing lower respiratory tract infections in critically ill pediatric patients
Background Lower respiratory tract infections are among the most common causes of fatality in children, particularly in critically ill patients in the PICU. Rapid and targeted antimicrobial therapy is crucial to improve their outcomes. The study aimed to assess the validity of the rapid molecular…
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Artikel Jurnal
Quantitative apparent diffusion coefficient mapping as a noninvasive tool for the histopathological subtyping of lung cancer: a prospective study
Background Lung cancer remains a leading cause of cancer-related mortality globally and in Egypt. The process of diagnosis usually includes a survey of clinical data, radiologic assessment, and histopathologic evaluation of tissue. Noninvasive differentiation of histological subtypes is crucial for…
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Evaluating quantitative dynamic contrast-enhanced MRI as an addition to prostate imaging reporting and data system version 2.1 for prostate cancer detection: a prospective study
Background Prostate cancer is a leading malignancy in men, and multiparametric MRI (mpMRI), particularly dynamic contrast-enhanced (DCE)-MRI, plays a key role in identifying and characterizing lesions. While prostate imaging reporting and data system (PI-RADS) v2.1 standardizes mpMRI reporting, it…
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Artikel Jurnal
Evaluation of endoscopic assisted curettage of benign cystic bone lesions
Background Benign bone lesions are a heterogeneous group of conditions with variable biological behaviour. Although open curettage has been traditionally used for simple and aneurysmal bone cysts, it is associated with notable morbidity, while percutaneous techniques may limit adequate…
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Artikel Jurnal
Validity of ROX index in predicting mechanical ventilation in patients with COVID-19 pneumonia in Alexandria Main University Hospital
Objective To study the predictability of ratio of oxygen saturation (ROX) index for the need of mechanical ventilation (MV) in coronavirus disease 2019 pneumonia patients treated using high frequency nasal cannula (HFNC). Design A prospective observational study. Setting Isolation units of the…
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Diagnostic value of intratumoral and peritumoral contrast-enhanced computed tomography-based texture analysis data in lung adenocarcinomas with anaplastic lymphoma kinase rearrangement and epidermal growth factor receptor mutation
Introduction Texture analysis (TA) has developed as a significant tool for the study of medical images, especially those of lung cancer. In this study, we aimed to assess the diagnostic value of TA data extracted from intratumoral and peritumoral parenchyma in predicting mutational alteration…
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Artikel Jurnal
Prevalence and risk factors of emotional and behavioral problems among intermediate and high school students in the southern region of Saudi Arabia
Background Adolescents face increasing social, emotional, and academic pressures, so it is important to know how common emotional and behavioral problems (EBPs) are and what factors put them at risk so we can support their mental health during this formative period. The study aimed to determine the…
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Artikel Jurnal
Dosimetry comparison between 3D conformal radiotherapy, intensity-modulated radiotherapy, and volumetric-modulated arc therapy technique for the concurrent chemoradiation of oral cavity squamous cell carcinoma stage III–IVA, B.
Background The objective of this study was to assess the amount of radiation received by specific areas of interest and organs at risk (OARs) in three different types of radiotherapy: 3D conformal radiotherapy (3D-CRT), intensity-modulated radiotherapy (IMRT), and volumetric-modulated arc treatment…
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Artikel Jurnal
Pheochromocytoma and paragangliomas in Basrah
Background Pheochromocytoma and paraganglioma (PPGLs) are rare, catecholamine-secreting tumors derived from chromaffin cells, which are diagnosed with paroxysmal or sustained hypertension. The disease can occur as sporadic or as part of a familial syndrome, which needs genetic testing, and is…
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Artikel Jurnal
Comparison between presence and absence of perirectal spacer in prostate cancer IMRT/VMAT radiotherapy regarding rectal dosimetry and toxicity
Background Due to the close proximity of the prostate to the anterior wall of the rectum, the perirectal spacer is considered one of the methods of decreasing dose to the rectum in case of prostate cancer radiotherapy. In our study, we present the effect of hyaluronic acid (HA) spacer mixture on…