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Case Reports in Pathology
ISSN 2090-679X · Wiley · 152 artikel di indeks
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MAML2-Rearranged Hidradenoma of the Breast: Clinicopathologic and Molecular Analysis of Four Patients
Hidradenoma (HA) is a rare, benign adnexal tumor typically arising in the skin, with only a few reported cases in the breast. Histologically, HA displays solid and cystic patterns with diverse cellular components. Although MAML2 gene rearrangement is observed in some cutaneous HAs, its significance…
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Invasive Lobular Carcinoma of the Male Breast With BRCA2 Mutation
Male breast cancer (MBC) is a rare condition, accounting for
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Pericardial Metaplastic Ossification With Widespread Bone Formation: A Case Report
Pericardial disease can present clinically as acute pericarditis, pericardial effusion, cardiac tamponade, and constrictive pericarditis (CP). Pericardial calcification is present in less than 25% of all cases of CP, and patients with this finding are at risk for developing additional cardiac…
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Basaloid-Solid Adenoid Cystic Carcinoma of the Breast: A Case Report and Literature Review
Solid-basaloid adenoid cystic carcinoma (SB-AdCC) of the breast is a rare neoplasm. We report the case of a 78-year-old woman who presented with a progressively enlarging right breast mass over 3 years. Clinical examination revealed a 6-cm mass with visible skin ulceration and right axillary…
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Reactive Nodular Fibrous Pseudotumor Presenting as Gastric Outlet Obstruction in a Young Adult Male Patient: A Case Report and Review of the Medical Literature
Mesenchymal proliferations involving the gastrointestinal tract are uncommon and often unexpected upon initial clinical presentation. Here, we are reporting a case of a 20-year-old male patient presenting to the hospital with abdominal pain and vomiting. Upon evaluation, the patient was initially…
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Primary Ewing's Sarcoma of the Sinonasal Region: A Rare Clinical Encounter
Ewing's sarcoma (EWS) is a highly aggressive tumor of neuroectodermal origin, rarely occurring in the sinonasal tract, particularly in adults. We report a 27-year-old male with long-standing nasal obstruction, initially misdiagnosed as nasal chondromesenchymal hamartoma. Surgical excision revealed…
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Ask-Upmark Kidney Disease: Case Report of a Rare Congenital Malformation
Ask-Upmark kidney disease is a congenital renal malformation characterized by segmental hypoplasia, leading to progressive impairment of renal function and severe hypertension. It is a rare anomaly that presents with various complications. A 14-year-old boy diagnosed with Ask-Upmark kidney was…
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A Case Report of Pigmented Purpuric Dermatosis With No Granuloma Formation: A 20-year Follow-Up Case Study
In a case of pigmented purpuric dermatosis with hyperlipidemia reported earlier to be persistent for over 20 years, the primary disease was cured by oral rinsing with ozone water; however, the remaining prominent pigmentation was not remarkably improved even with oral administration of vitamin C…
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Uterine PEComa With Lymphangioleiomyomatosis (LAM)-Like Features: A Case Report
Perivascular epithelioid cell tumors (PEComas) of the uterus are rare mesenchymal neoplasms characterized by myogenic and melanocytic differentiation. These tumors can mimic other uterine mesenchymal tumors in their clinical presentation and morphology. We report a case of a 58-year-old woman who…
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Distant Metastases of an Atypical Meningioma 14 Years Later After Primary Tumor Resection: A Case Report and Review of the Literature
Meningioma, one of the most common neoplasms of the central nervous system in adults, is most likely derived from the meningothelial cells of the arachnoid matter. Although most meningiomas have a benign clinical course and a relatively good prognosis, some can demonstrate more aggressive…
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Pathological Study of Rare Malignant Cardiac Tumors: A Case Series of Five Patients
Malignant cardiac tumors are uncommon but highly aggressive growths that may develop within the heart or spread from other primary locations. Considering the significance of pathological studies and the dissemination of findings on malignant cardiac tumors in advancing medical knowledge and…
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DEK::AFF2 Fusion-Associated Sinonasal Carcinoma With Intracranial and Orbital Involvement
Sinonasal carcinomas encompass a molecularly heterogeneous group of malignancies. DEK::AFF2 fusion-associated carcinoma is a recently recognized subtype of nonkeratinizing squamous cell carcinoma characterized by deceptively bland morphology yet clinically aggressive behavior. We report the case of…
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A Rare Case of a Non-Invasive Vaginal Urothelial Carcinoma Demonstrating a Clonal Relationship With a Metachronous Non-Invasive Bladder Urothelial Carcinoma
Non-invasive vaginal urothelial carcinomas (UCs) are extremely rare and are almost always associated with a non-invasive bladder UC. The pathogenesis of these rare vaginal lesions is uncertain. They may represent a primary vaginal tumour or they may arise from a urinary tract UC, in which tumour…
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Endometriosis-Associated Ovarian Carcinosarcoma Featuring Well-Differentiated Adenocarcinoma and Fetal Rhabdomyoma-Like Mesenchymal Components: An Unusual Case Report—With Molecular Analysis
Ovarian carcinosarcoma typically comprises high-grade carcinoma and sarcoma components. We report a case of a woman in her 40s with endometriosis-associated ovarian carcinosarcoma exhibiting an unusual presentation of well-differentiated adenocarcinoma and rhabdomyosarcoma. The patient underwent…
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Challenges in the Diagnosis of Concurrent T-Lymphoblastic Leukemia/Lymphoma and Thymic Neuroendocrine Carcinoma: A Case Report
The co-occurrence of T-lymphoblastic leukemia/lymphoma and thymic neoplasia is a rare event that can present a diagnostic challenge. In this case report, we describe a 31-year-old man who was found to have thymic neuroendocrine carcinoma and T-lymphoblastic leukemia/lymphoma 2 years after initial…
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Pulmonary Adenoleiomyomatous Hamartoma: Case Report of a Rare Entity With Comprehensive Literature Review
Pulmonary adenoleiomyomatous hamartomas represent a rare and intriguing entity in pulmonary pathology. This study presents a unique case of adenoleiomyomatous hamartoma along with a comprehensive analysis of 14 cases identified through a systematic review of the literature. A 69-year-old Caucasian…