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Journal of Analytical Methods in Chemistry
Scopus
ISSN 2090-8873 · Wiley · 1.132 artikel di indeks
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Artikel Jurnal
Comprehensive and Rapid Chemical Profiling of Cirsium japonicum DC Utilizing UHPLC-Q-Orbitrap MS With Parallel Reaction Monitoring
Cirsium japonicum, a traditional medicinal plant, has been widely used for its therapeutic properties in treating various ailments. However, a comprehensive analysis of its chemical composition remains limited, hindering a full understanding of its chemical basis and pharmacological activities…
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Artikel Jurnal
Enhanced Detection of Organochlorine Pesticide Residues in Sesame Seeds (Sesamum indicum L.) Using Advanced GC-MS/MS Techniques
Considering the economic and edible values of sesame seeds, it is important to monitor sesame seed for the safety of consumers and for international trade as it helps the country government and suppliers as products to gain market acceptance more effectively. The objective of this study was to…
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The Making of the Vindolanda Wooden Writing Tablets: A Noninvasive Multianalytical Protocol for the Characterisation of Black Roman Inks
Within the ‘Making History’ project, the British Museum investigated the materiality of the Vindolanda ink writing tablets for the first time, with a particular focus on the possible differentiation of the ink sources employed. Thanks to the application of complementary scientific techniques, it…
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Characterization and Mechanism Prediction of Active Components in Fuganlin Oral Liquid for Respiratory Tract Infections Using UPLC–Q-TOF–MS and Network Pharmacology
Fuganlin oral liquid (FOL) has been clinically employed for the treatment of pediatric qi deficiency colds, manifesting symptoms such as fever, cough, asthma, and sore throat. However, the chemical composition and bioactive components of FOL have not been clearly elucidated. In this study, a…
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Artikel Jurnal
Exploration of Potential Antidepressant Active Ingredients of Albiziae Flos via HS–GC–MS, Chemometrics, and Network Pharmacology
Albiziae Flos (AF) is a traditional Chinese medicine with an extensive historical background. This study presented an integrated approach combining headspace–gas chromatography–mass spectrometry (HS–GC–MS), chemometrics, and network pharmacology to comprehensively evaluate the volatile components…
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Rapid Detection of Tetracycline Residues in Milk Using Colorimetric Sensor Based on Polymethylmethacrylate (PMMA) and Polystyrene (PS) Polymers
In this study, the colorimetric approach is applied on an indicator strip for tetracycline detection in milk residue. Indicator strips made from PMMA-concentrated H2SO4 (9:1), PMMA-Mecke (9:1), and PMMA-Marquis (9:1) are the best compositions that can detect tetracycline within 10 s. The test…
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Effect of Plastic Composition in the Combustion Material on the Persistent Organic Pollutant Content in Smoked Dried Shiitake Mushroom
Smoking is a traditional preservation method in Vietnam, widely applied to shiitake mushrooms (Lentinula edodes) as well as meats, yet the use of plastic-contaminated fuels poses emerging food safety concerns. This study provides the first congener-specific characterization of polycyclic aromatic…
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Harnessing the Structural Variability of Doxycycline Hyclate: Mechanistic Insights and Comparative Assessment of Four Chemically Diverse Spectrophotometric Pathways
Four distinct, chemically asynchronous spectrophotometric pathways each tapping into a different reactive node of the polyfunctional doxycycline hyclate (DOX) framework were planned to bypass the limitations of single mechanism assays. It works amazingly well. By exploiting the drug’s inherent…
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Artikel Jurnal
Development and Validation of an UPLC–MS/MS Method for Remodelin Quantification in Mouse Plasma and Tissues: Application to Biodistribution and Ultrastructural Assessment
Remodelin, a selective N-acetyltransferase 10 (NAT10) inhibitor, has emerged as a promising therapeutic candidate for degenerative diseases with nuclear abnormalities and acetylation dysregulation. However, its pharmacological development has been hindered by the lack of a sufficiently sensitive…
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LC-Triple Quadrupole MS Enables Sample Classification in Viscum combreticola: Detecting Subtle Photochemical Isomerization in Hydroxycinnamic Acid Derivatives
High-resolution MS techniques such as time-of-flight (TOF)-MS are preferred for putative metabolite identification due to their unprecedented high resolution and accuracy in metabolomics studies. However, exploring cost-effective alternative instruments for routine analyses would be advantageous…
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QTOF and Orbitrap Technologies in Modern Pesticide Analysis: Applications in Residue Detection and Degradation Pathway Elucidation
QTOF and Orbitrap techniques, as advanced mass spectrometry tools, show great potential in the field of pesticide residue analysis and degradation product identification. This paper reviews the application of these two techniques in pesticide residue analysis and degradation product identification…
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Artikel Jurnal
Quantitative Analysis of Flavonols and Their Glycosides and Gastrointestinal Transformation of Flavonol Glycosides in Yinxing Mihuan Oral Solution
Yinxing Mihuan Oral Solution (YMOS) is extensively utilized in the clinical treatment of cardiovascular and cerebrovascular diseases (CCVDs), with flavonols and their glycosides identified as the primary active ingredients. Currently, there are relatively few established quantitative methods…
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A Simple and Accurate LC–MS/MS Method for the Determination of Indobufen in Human Plasma and Its Clinical Application
As an antithrombotic agent, indobufen is widely used in China. However, the relationship between drug concentration and therapeutic efficacy in specific patient populations remains unclear. Therefore, it is crucial to establish a method for quantifying indobufen concentrations in human plasma to…
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Development of a Fluorometric Method for Carbaryl Determination Using MCM-41 Containing Cetyltrimethylammonium
This study investigated a solid base reagent for the fluorometric determination of carbaryl residues in vegetables. The method is based on the reaction between carbaryl and Mobil Composition of Matter No. 41 (MCM-41) containing cetyltrimethylammonium (CTA), denoted as MCM-41-CTA, which produces…
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Artikel Jurnal
A Colorimetric Multimetabolite Assay for Quantitative Measurement of Keto Acids in Urine for At-Home Monitoring of Metabolic Disorders
Inborn errors of metabolism such as phenylketonuria (PKU) and maple syrup urine disease (MSUD) can cause severe developmental problems. Both conditions can lead to harmful levels of keto acids in biofluids—phenylpyruvic acid (PPA) in PKU and branched-chain α-keto acids in MSUD. Monitoring urinary…
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