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Bulletin of Faculty of Pharmacy Cairo University
ISSN 2090-9101 · Faculty of Pharmacy, Cairo University · 76 articles in the index
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Journal Article
Evaluation of the Phytochemical components and in vitro anti-inflammatory activities of Eucalyptus camaldulensis
Phytochemicals such as alkaloids, flavonoids, and terpenoids are known for their medicinal properties, including anti-inflammatory effects. This study analyzed the phytochemical composition of Eucalyptus camaldulensis leaf extracts and evaluated its’ in vitro anti-inflammatory potential. Leaves of…
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Journal Article
Formulation Strategies for Next-Generation Bispecific Antibodies: Design Considerations and Stability Implications
Bispecific antibodies (BsAbs) represent a transformative class of next-generation biologics, enabling simultaneous binding to two targets and offering mechanisms of action beyond conventional monoclonal antibodies. Their growing clinical success, particularly in T-cell–redirecting therapies, has…
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Journal Article
Developing a Multicriteria Decision Analysis Framework to Establish Differential Cost-Effectiveness Thresholds for Orphan Drugs in Egypt
Introduction High pricing of orphan drugs often restricts patient access. As orphan medicines are usually not cost-effective according to traditional thresholds, countries may choose not to consider the cost-effectiveness criterion in pricing and reimbursement decisions or may adopt higher…
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Journal Article
Centella Asiatica: Recent cosmeceutical uses for treatment of skin diseases
Centella asiatica is one of the well-known herbal species used in traditional medicine across Asia such as India, Indonesia, and China. It had been used as a medicinal plant for hundreds of years. Besides its general pharmacological activities such as neuroprotection, anti-cancer and anti-diabetes…
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Journal Article
The Impact of Social Media on Garlic Burn Incidents: Exploring the Risks of Home Remedies
Background: The use of medicinal plants is increasingly popular, fueled by online endorsements and a growing interest in natural remedies. Garlic (A. sativum), a well-known herbal species, is often touted for its medicinal properties and used to treat various ailments, including coughs and colds in…
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Journal Article
Resveratrol: A promising candidate for treating a range of diseases
Traditional Chinese Medicine (TCM), rooted in herbal remedies and balance, spans millennia, viewing illness as Qi imbalances. The therapeutic applications of resveratrol within the realm of TCM represent a fascinating intersection of ancient wisdom and modern scientific research. Resveratrol, a…
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Journal Article
Survey on Seed Biology and Pharmacological Properties of Four Important Species
Medicinal and aromatic plants are gaining more importance because of their potential application in food, pharmaceutical and fragrance industry. Medicinal and aromatic plants have been used in cosmetics, perfumery, pharmaceuticals and food flavoring since ancient times, because of the presence of…
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Journal Article
The Role of Traditional Chinese Medicine (TCM) in Battling Neurodegenerative Disorders
Aging and aging-related diseases pose significant challenges to global public health, necessitating the urgent development of effective anti-aging therapies. In this context, Traditional Chinese Medicine (TCM) emerges as a vital complementary and alternative approach to managing these conditions…
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Journal Article
In Vivo Pharmacokinetic Evaluation of a Gastro-retentive Triple Drug Delivery System Utilizing Natural Polymers for Enhanced Helicobacter pylori Eradication
This study evaluates the in vivo pharmacokinetics of triple-drug gastro-retentive formulation (metronidazole- Plantago ovata seed mucilage/ clarithromycin- Abelmoschus esculentus fruit mucilage/enteric-coated pantoprazole) for Helicobacter pylori eradication, with a focus on pharmacokinetic…
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Journal Article
Comparative analysis of tuberculosis treatment costs: drug-resistant vs. drug-sensitive cases in Vietnam
This study analyses the economic and clinical implications of treating pulmonary tuberculosis (TB), focusing on direct treatment costs and patient outcomes at Da Nang Hospital for Lung Diseases in Vietnam. Data were collected from 448 inpatient TB cases throughout 2022, encompassing both…
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Journal Article
The Efficacy of Essential Oils in Promoting Youthful Skin: A review
Background Skincare essential oils [EOs] are gaining recognition for their effectiveness as natural solutions to promote youthful skin. These concentrated plant extracts provide a variety of benefits, including hydration, antioxidant protection, and anti-inflammatory properties. Purpose This review…
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Journal Article
A Cost Variation Analysis of Various Statin Preparations Available in the Egyptian Market
Introduction: Dyslipidemia is one of the main risk factors for cardiovascular diseases. Statin preparations are the most effective lipid-lowering preparations that reduce the risk of mortality related to cardiovascular diseases. In the Egyptian market, various statin preparations have different…
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Journal Article
Eco-friendly HPTLC Determination of Paracetamol, Caffeine, Drotaverine HCl and Two of their Official Impurities; Application to Assay and Content Uniformity Testing of Tablet Dosage Form
The present work is focused on developing and validating an eco-friendly, sustainable and sensitive HPTLC method for the purpose of simultaneous determination of a five component mixture. This mixture includes paracetamol, caffeine, drotaverine HCl and the official impurities of the first two…
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Journal Article
Nanoemulsion formulation of pregabalin for enhanced nose to brain delivery and biological tracking using radiolabeling with 99mTc
Pregabalin is a γ-aminobutyric acid analogue used for the treatment of neuropathic pain, seizures, and anxiety disorders. After oral administration, its level of brain penetration is rather modest. In this research, pregabalin was formulated successfully as a nanoemulsion. To track the…
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Journal Article
Ameliorative Effect Of Aqueous Leaf Extract Of Cola Acuminata On Mercury Chloride- Induced Neurotoxicity In Male Wistar Rat
Ameliorative effect of aqueous leaf extract of Cola acuminata(ALECA) on mercury chloride- induced neurotoxicity in male Wistar rat was investigated. Thirty six (36) male Wistar rats weighing 120g-150g were randomly divided into six groups; group I: received 0.5ml normal saline; group II: received…
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Journal Article
Smart Spectrophotometric Approaches for Estimation of Difluprednate in Existence of Its Synthetic Precursor and Alkaline Degradation Product; Comparative Statistical Studies and Analytical Ecological Appraisal
Scientists are currently attempting to lessen the harmful effects that chemicals and solvents have on the environment. The current work suggests four sensitive and sustainable spectrophotometric techniques for quantifying difluprednate (DIF) in presence of hydrocortisone acetate, which is a…
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Journal Article
A Comprehensive Review on Solenostemma argel (Del.) Hayne, An Egyptian Medicinal Plant
Solenostemma argel (Del.) Hayne, commonly known as Arghel or Hargal, is a desert plant belonging to the family Apocynaceae. It has been used in traditional medicine in various countries, including Saudi Arabia, Egypt, Libya, Algeria, and Sudan, where it is the primary source. The review is aimed at…
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Journal Article
Cost Variation Analysis of Biological Drugs, Corticosteroids and Conventional Treatments used for Rheumatoid Arthritis in the Egyptian Market
Background Rheumatoid arthritis (RA) is an autoimmune disease where the body attacks healthy cells primarily in the hands, knees, and wrist joints, causing chronic inflammation and pain. This process damages joint tissues, leading to deformation and imbalance. Materials and Methods The cost of…
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Journal Article
A Cost Variation Analysis of Drugs Available for the Treatment of Hypothyroidism in the Egyptian Market
Background: A sizable portion of each nation's overall healthcare costs is being spent on pharmaceutical products. Hence, alternative and competing healthcare strategies or multiple brands of a specific prescription must be prioritized, especially in the case of chronic illnesses for countries with…
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Journal Article
Design and validation of eco-friendly chemometric-assisted spectrophotometric methods for the simultaneous determination of chlorzoxazone, paracetamol, and aceclofenac in the presence of their main impurities
Objective: The goal of this work is to develop and validate eco-friendly spectrophotometric methods for the simultaneous determination of chlorzoxazone (CHZ), paracetamol (PAR), and aceclofenac (ACF) in the presence of their major impurities, specifically 2-amino-4-chlorophenol (ACP), 4-aminophenol…