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Journal of Traditional Chinese Medical Sciences
Scopus
ISSN 2095-7548 · Elsevier · 558 artikel di indeks
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Artikel Jurnal
Antidepressant mechanisms of a food-medicine homologous compound concentrate from Hemerocallis citrina Baroni: Regulation of PI3K/AKT/BDNF signaling pathway in preclinical models
Objective: To determine the optimal dosing ratio of the herbal components within compound Hemerocallis citrina Baroni (H. citrina) extract concentrate (CHEC), evaluate its antidepressant effects in zebrafish and mouse models of depression, and elucidate the underlying mechanisms with a particular…
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Artikel Jurnal
Applications of Panax ginseng C. A. Mey. and its derivatives in cognitive and emotional dysregulation: A perspective from medicine-food homology
Mental health issues, including cognitive impairment, anxiety, and depression, have become a major global health challenge. Notably, conventional pharmacological treatments are often accompanied by adverse reactions. The traditional Chinese medicine concept of “Medicine and Food Homology (MFH)”…
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Artikel Jurnal
Fermented Suan Zao Ren ameliorates sleep in a mouse model of blood-deficiency insomnia by modulating hippocampal monoamines
Objective: To investigate the pharmacodynamic effects of Ziziphus jujuba Mill. var. spinosa (Bunge) Hu ex H. F. Chou (Z. jujuba, Suan Zao Ren) fermented with the fungus of Poria cocos (Schw.) Wolf (P. cocos strain) and Massa Medicata Fermentata (MMF) on hippocampal monoamine neurotransmitters in…
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Artikel Jurnal
Preparation and evaluation of a nasal nanogel formulation of perillaldehyde for treating plateau insomnia
Objective: To investigate the use of perillaldehyde (PAE) for treating plateau insomnia and to develop a stable intranasal PAE nanomicelles in situ gel (PAE/NMs-INSG). Methods: A mouse model of plateau insomnia was established in this study. Sleep latency/duration and brain…
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Artikel Jurnal
The effects of Ganmai Dazao decoction on depression and anxiety: A systematic review and meta-analysis
Objective: To evaluate the efficacy and safety of Ganmai Dazao (GMDZ) decoction alone and in combination with antidepressant medication or psychotherapy for depression. Methods: We searched seven electronic databases from inception to December 2025. Two assessors extracted the data and…
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Artikel Jurnal
Efficacy and safety of Ruyi Zhenbao tablet in patients with lumbar disc herniation: A protocol for a multicenter, randomized, positive-controlled trial
Objective: To evaluate the efficacy and safety of Ruyi Zhenbao tablet (RYZBT), a traditional Tibetan medicinal formula, for the treatment of lumbar disc herniation (LDH), that is frequently associated with lower back pain (LBP), through rigorous randomized controlled trials (RCTs). Methods: This…
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Artikel Jurnal
Electroacupuncture ameliorates bladder dysfunction and fibrosis in diabetic rats: Underlying role of transient receptor potential vanilloid 1 in the dorsal root ganglion
Objective: To assess the therapeutic effects of electroacupuncture (EA) in a rat model of diabetic cystopathy (DCP) and examine its impact on the expression of transient receptor potential vanilloid 1 (TRPV1) in the dorsal root ganglion (DRG). Methods: Sixty male Sprague-Dawley rats were divided…
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Artikel Jurnal
Polygonatum sibiricum Red. and its polysaccharides in cognitive improvement: Pharmacological mechanisms and therapeutic potential
Cognitive impairment is a growing public health concern associated with aging, neurodegenerative diseases, and chronic stress. Polygonatum sibiricum Red. (P. sibiricum, Huang Jing), a traditional Chinese medicinal herb, is used to reinforce qi, strengthen the spleen, and nourish yin. Recent studies…
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Artikel Jurnal
Telomere-related gene signature as a prognostic and immunogenomic classifier in stomach adenocarcinoma
Objective: To profile telomere-related genes (TRGs) to develop a robust prognostic tool for stomach adenocarcinoma (STAD) and explore their associations with immune regulation and treatment response. Methods: A total of 2083 TRGs were analyzed in The Cancer Genome Atlas (TCGA)-STAD cohort (412…
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Artikel Jurnal
Applications and challenges of traditional Chinese medicine in gastrointestinal disease treatment: A review
Gastrointestinal (GI) diseases are common multifactorial disorders involving chronic inflammation, epithelial barrier disruption, immune dysregulation, gut microbiota imbalance, and abnormalities in motility and gut–brain interactions. Conventional pharmacotherapies (e.g., antibiotics, acid…
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Artikel Jurnal
Rheum palmatum L.–Prunus persica (L.) Batsch herb pair restores endometrial receptivity in adenomyosis
Objective: To investigate whether herbal pair Rheum palmatum L. (R. palmatum; Da Huang)–Prunus persica (L.) Batsch (P. persica; Tao Ren) (RP) can restore endometrial receptivity and mitigate adenomyosis (AM)-associated infertility by regulating dysregulated glycolytic metabolism. Methods: An AM…
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Artikel Jurnal
Effects of Qixuekang oral liquid in leukopenia during chemotherapy and radiotherapy in patients with malignant tumors: A randomized, double-blind, placebo-controlled, multicenter study
Objective: To assess the efficacy and safety of Qixuekang oral liquid in the treatment of leukopenia during chemotherapy and radiotherapy. Methods: This randomized, double-blind, placebo-controlled, multicenter clinical trial was conducted between July 2018 and May 2021. A total of 234 patients…
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Artikel Jurnal
Beyond pharmaceuticals: Integrating Chinese culinary medicine with modern nutritional science for holistic diabetes management
The prevalence of diabetes mellitus in China has increased from
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Artikel Jurnal
Health benefits of honey: A critical review on the homology of medicine and food in traditional and modern contexts
Honey, a natural substance, has long been valued for its dual role in both food and medicine in diverse cultural traditions, particularly in traditional Chinese medicine (TCM). It is rich in sugars, amino acids, enzymes, polyphenols, and flavonoids that contribute to its antimicrobial, antioxidant…
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Artikel Jurnal
Exploring the therapeutic potential of propolis in managing diabetes: A preclinical study
Objective: To evaluate the therapeutic potential and underlying mechanisms of action of propolis in db/db mice. Methods: The chemical composition of propolis was analyzed using UHPLC-MS/MS. Thirty mice, including six wt/wt and 24 db/db mice, were randomly assigned to four groups (n = 6 per group)…
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Artikel Jurnal
The application of medicine and food homology in the management of chronic heart failure
Chronic heart failure (CHF) is a pathological state in which the cardiac ejection fraction is insufficient to meet an individual's metabolic needs owing to changes in the cardiac structure or function. Various etiologies such as myocardial infarction and inflammation are implicated, and the main…
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Artikel Jurnal
Exploration of the regulatory mechanism of norcantharidin on sine oculis homeobox homolog 4 in colon cancer using transcriptome sequencing and bioinformatic
Objective: To explore the key molecules regulated by norcantharidin (NCTD) in colon cancer treatment. Methods: We used cell counting kit-8 and 5-ethnyl-2′-deoxyuridine/Hoechst staining assays to study the effects of NCTD on cell proliferation in colon cancer. Annexin V-fluorescein…
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Artikel Jurnal
Mechanism of Jiawei Sanpian decoction in treating migraine through network pharmacology, molecular docking, and experimental studies
Objective: To analyze and validate how Jiawei Sanpian decoction treats migraines by integrating network pharmacology, molecular docking technology, and experimental studies. Method: Using network pharmacology, the chemical components and core target proteins of the Jiawei Sanpian decoction were…