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Engineering
Scopus
ISSN 2095-8099 · Elsevier · 2,183 articles in the index
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Journal Article
The Serum-Derived Extracellular Vesicle N-Glycome as a New Biosignature for Childhood Epilepsy
Childhood epilepsy poses a serious threat to patients’ growth, development, and life safety, creating an urgent need for precise, non-invasive, and longitudinally monitorable biomarkers. Previous studies have confirmed that extracellular vesicles (EVs) with abnormal N-glycosylation modifications…
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Journal Article
Superior Electrocatalytic Oxygen Evolution of Nickel-Based Metals Modulated by Controllable Graphene Layers via Interfacial Redox Process
Metallic Ni is widely used for oxygen evolution reaction (OER) catalysis. It acts as a precatalyst and undergoes surface reconstruction into NiOOH, which is the active species used in OER. Consequently, OER performance is highly related to the NiOOH structure, which is determined by the…
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Journal Article
Fucosylated IgG Contributes to Adipose Tissue Dysfunction During Aging
Immunoglobulin G (IgG) is recognized as a key regulator of metabolic dysfunction and fibrosis in adipose tissue, and its functional properties are tightly regulated by its glycosylation profile. However, the role of IgG glycosylation in adipose aging remains unclear. Here, we performed…
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Journal Article
Rational Modulation of Pt d Electrons to Significantly Enhance the Catalytic Dehydrogenation Performance of Liquid Organic Hydrogen Carriers
Understanding the intrinsic features of dehydrogenation reactions of liquid organic hydrogen carriers (LOHCs) is a formidable challenge due to the combined impact of electronic and geometric effects. Herein, we constructed a series of Pt/MOx catalysts (CeO2, MgO, ZrO2, TiO2, Al2O3, or SiO2) with…
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Journal Article
Moving Beyond a Zero Tolerance Mindset: Embracing Action Errors in Construction
Action errors—unintentional deviations from goals, rules, or standards—are an inevitable part of work in construction. Understanding how individuals and organizations can embrace and “learn through errors” (i.e., how to handle them effectively) is crucial for contributing to project success…
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Journal Article
Halotolerant PGPB Delivered by Drip Irrigation Improve Crop Yield and Quality Through Changes in the Soil Bacterial Community
Halotolerant plant growth-promoting bacteria (PGPB) have great potential for alleviating salinity stress in crops. However, the current methods used with these bacteria are typically based on one-time inoculations, including soil basal application, seed dressing and plant infestation, all of which…
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Journal Article
A Comparative Mechanistic Study of Live-Cell Glycocalyx Engineering: Improving Adoptive Cell Therapies Against B Lymphoma
Adoptive cell therapies (ACTs) have achieved remarkable clinical success in treating cancers; however, their broader application is greatly impeded by high cost and restricted antigen specificity. Recently, engineering the glycocalyx has provided a convenient transgene-free means to design ACTs…
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Journal Article
Deep Reinforcement Learning-Driven Multi-Omics Integration for Constructing gtAge: A Novel Aging Clock from the IgG N-Glycome and Blood Transcriptome
Previous studies have demonstrated that the immunoglobulin G (IgG) N-glycome and transcriptome are potential biochemical signatures of chronological and biological ages, and several aging clocks have been developed. By integrating the IgG N-glycome and transcriptome, we propose a novel aging clock…
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Journal Article
Absolute Quantification of Aging-Associated Glycans in IgG for Biological Age Prediction: Insights from Glycomics and Transcriptomics
Immunoglobulin G (IgG) N-glycans are associated with aging. In this study, we introduce a novel strategy for discovering aging-associated IgG glycans and establish a prediction model on the basis of their absolute concentration alterations. We employed glycomic quantification technology to identify…
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Journal Article
IgG Fucosylation: An Emerging Key Player in the Treatment of Severe COVID-19
Protein glycosylation is one of the most vital modifications. Understanding the role of protein glycosylation in coronavirus disease 2019 (COVID-19) is the key in elucidating its pathogenesis and developing therapeutic strategies. We conducted a case-control study to examine the total fucosylation…
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Journal Article
Targeting Plasmid Conjugation with Cinnamic Acid: A Novel Approach to Combat Antibiotic Resistance
The global spread of antibiotic resistance genes (ARGs) continues to worsen, with plasmid-mediated conjugation serving as a major transmission route. Although developing conjugation inhibitors to block this process is a promising strategy, current options are limited by toxicity and poor in vivo…
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Journal Article
Neural Network-Based Switching Output Regulation Control for High-Speed Nano-Positioning Stages
This study establishes a high-speed nano-positioning stage composed of a symmetrically driven structure with multiple parallel-bonded thin piezoelectric ceramic layers capable of performing micro- or nano-scale manipulations. Accordingly, a neural-network-based switching output regulation…
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Journal Article
Contrasting Macroevolutionary Patterns in the Human N-Glycosylation Pathway
Building on coding mutations and splicing variants, post-translational modifications add a final layer to protein diversity that operates at developmental and physiological timescales. Although protein glycosylation is one of the most common post-translational modifications, its evolutionary origin…
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Journal Article
Multi-Frequency Dual-Echo Magnetic Resonance Imaging for Real-Time and Artifact-Free Magnetic Robot Navigation
Magnetic resonance imaging (MRI) systems, outfitted with internal gradient coils capable of manipulating magnetic gradients in three-dimensional (3D) space, offer an intriguing platform for the navigation of medical magnetic robots. These robots offer considerable promise for applications in…
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