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口腔疾病防治
Scopus
ISSN 2096-1456 · Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases · 1.550 artikel di indeks
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The role and research progress of bacteria in nifedipine-induced gingival hyperplasia
Nifedipine-induced gingival overgrowth (NIGO) refers to gingival hyperplasia caused by long-term use of the hypertensive drug nifedipine (NIF), and it is a drug adverse reaction. NIGO is characterized by a high incidence rate and a large patient base, and it is one of the most common types of…
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Correlation study between ankyloglossia and mandibular development and lower anterior crowding
Objective To study the association between ankyloglossia and sagittal mandibular development impairment as well as lower anterior dental crowding, providing a reference for clinical practice. Methods This study was approved by the hospital's Medical Ethics Committee. A total of 100 patients aged…
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Research progress on the role of Porphyromonas gingivalis in the progression of tumor
Periodontitis is a chronic inflammatory disease. The heterotopic colonization of periodontal pathogens results in the development of several systemic diseases. Porphyromonas gingivalis (P. gingivalis), a key pathogen for periodontitis, has been linked to the development of various cancers, such as…
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Expert consensus on neoadjuvant PD-1 inhibitors for locally advanced oral squamous cell carcinoma (2026)
Oral squamous cell carcinoma (OSCC) is a common head and neck malignancy. Approximately 50% to 60% of patients with OSCC are diagnosed at a locally advanced stage (clinical staging III-IVa). Even with comprehensive and sequential treatment primarily based on surgery, the 5-year overall survival…
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Effects of oral microbiota and immune cells on oral leukoplakia: a Mendelian randomization and mediation analysis
Objective To assess the causal association between specific oral microbiota and the risk of oral leukoplakia (OLK) using a Mendelian randomization (MR) approach, and to elucidate the potential mediating role of immune cells. Methods Summary statistics from genome-wide association studies (GWAS) of…
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Age-related variations in the oral microbiome revealed by a large population-based study from National Health and Nutrition Examination Survey
Objective To explore the characteristics of the diversity and composition of oral microbial flora with age, and to provide a reference for understanding the succession of oral microecology at different ages. Methods Oral rinse 16S rRNA (V4 region) sequencing data from 9 021 participants 14-69 years…
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Research progress on oral microbiome in oral squamous cell carcinoma
The homeostasis of the oral microbiome is essential for maintaining host health, and its disruption can contribute to the development of both oral and systemic diseases. The oral microbiome influences the initiation and progression of oral squamous cell carcinoma (OSCC) through multiple mechanisms…
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Identification of autoinducer-2 in Streptococcus mutans membrane vesicles and effect of membrane vesicles on biofilm formation
Objective To investigate whether membrane vesicles (MVs) of Streptococcus mutans （S.mutans） contain autoinducer-2 (AI-2) and to preliminarily explore the effects of these MVs on the growth and biofilm formation of S. mutans. Methods MVs were isolated from the S. mutans UA159 strain using…
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Research progress on chronic mucocutaneous candidiasis
Chronic mucocutaneous candidiasis (CMC) is an infectious phenotype characterized by recurrent or persistent infections caused by Candida species that affect the skin, nails, oral, and genital mucosae for a duration exceeding six months. Current research suggests that CMC is an immunodeficiency…
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Study on the in vivo effects of 5T magnetic resonance imaging on the dental pulp and periodontal ligament in young adults
Objective To evaluate the performance of 5T magnetic resonance imaging (MRI) in visualizing dental pulp and periodontal ligament (PDL) tissues in vivo in the young adult population, thereby providing a basis for the application of high-field MRI technology in clinical oral examinations. Methods The…
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Research progress on the orthodontic treatment of permanent teeth with incomplete root development
Malocclusion is one of the most common oral conditions in children and adolescents. To prevent its progression, the demand for earlier orthodontic intervention during the early permanent dentition has been increasing. However, at this stage, the roots of some teeth are not yet fully developed…
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Mechanisms and therapeutic advances of antimicrobial peptides in periodontal regeneration
Periodontitis leads to progressive destruction of periodontal supporting tissues, and conventional anti-infective therapies often fail to simultaneously achieve infection control and tissue regeneration. Due to the increasing threat of antibiotic resistance, the development of novel bioactive…
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The prediction model of incident dental caries in 5-year-old children in Beijing
Objective To explore the influencing factors of incident caries at age 5 among caries-free 3-year-old children in Beijing, construct a machine learning prediction model based on oral health behavioral data, and provide a scientific basis and practical tool for early risk identification, stratified…
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Association between complete edentulism and incident cardiovascular disease among older adults: a retrospective cohort study
Objective To explore the association between baseline complete edentulism and the risk of incident cardiovascular disease (CVD) in older adults, and to verify the consistency across clinical subgroups and robustness of the findings, providing evidence for early CVD risk identification and…
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Deep learning-based multimodal data fusion: applications and research progress in oral diseases
With the rapid advancement of artificial intelligence, deep learning-based multimodal data fusion technology has found increasing applications in the field of dental and stomatological diseases, and it has demonstrated great potential. This technology constructs deep neural networks to…
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Analysis of influencing factors for preoperative dental anxiety in patients undergoing dental implant surgery
Objective To investigate and analyze the influencing factors and intervention strategy preferences of preoperative dental anxiety in patients undergoing oral implant surgery, and to provide a basis for the clinical formulation and implementation of targeted interventions. Methods This study was…
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Oral health management dilemmas affecting patients with chronic periodontitis in underdeveloped regions: a descriptive phenomenological study
Objective To deeply explore the systemic management dilemmas affecting patients with chronic periodontitis in underdeveloped regions, providing practical pathways for achieving oral health equity. Methods This study has been reviewed and approved by the Medical Ethics Committee, and written…
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Mechanistic study of regulatory T cells resisting ferroptosis under hypoxic stress in oral squamous cell carcinoma
Objective To explore the metabolic molecular mechanism of regulatory T cells (Tregs) resisting ferroptosis under a hypoxic stress microenvironment, and to provide scientific support for finding intervention targets to improve the immune microenvironment of oral squamous cell carcinoma (OSCC)…
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