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Brain Science Advances
ISSN 2096-5958 · SAGE Publishing · 268 articles in the index
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Journal Article
Transcranial direct current stimulation for pediatric learning disabilities: A narrative review
Learning disabilities in children involve executive dysfunctions, cognitive flexibility, inhibitory control, and emotional regulation, which may contribute to academic failure and psychosocial maladjustment. Despite standard interventions, many children continue to have cognitive-behavioral…
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Journal Article
CDESD: The Chinese Disyllabic Emotional Speech Database
Background: Existing emotional speech corpora do not always meet the need for brief, systematically characterized Mandarin stimuli in cognitive and affective neuroscience research. This study developed the Chinese Disyllabic Emotional Speech Database (CDESD) to address these methodological gaps…
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Journal Article
Association of hyperuricemia with acute ischemic stroke: A case-control study
Background: Stroke is a leading cause of death and disability worldwide. The association between serum uric acid and acute ischemic stroke (AIS) remains controversial. We aimed to evaluate the association between hyperuricemia and AIS, including stroke type, subtype, severity, and outcome. Methods…
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Journal Article
Postoperative Parameter Adjustment and Therapeutic Efficacy of Vagus Nerve Stimulation in Drug-Resistant Epilepsy
Background: Vagus nerve stimulation (VNS) is a recognized palliative surgical therapy for drug-resistant epilepsy (DRE). However, optimal postoperative parameter adjustment strategies to maximize efficacy remain an area of active investigation, particularly concerning different etiologies and…
Also available at: DOAJ
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Journal Article
Long-Term Outcomes and Recurrence of Rathke’s Cleft Cysts Post Endoscopic Endonasal Resection
Background: Rathke’s cleft cysts (RCCs) are benign sellar and suprasellar lesions. Most are treated conservatively, while others require surgery, usually via a transsphenoidal intervention. However, long-term outcomes of surgical intervention remain challenged by the risk of cyst recurrence, which…
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Journal Article
A Multidimensional “Source-Dynamics-Function-Structure” Magnetic Resonance Imaging Framework for Characterizing the Pathophysiological Imaging Profile of Moderate-to-Advanced Parkinson’s Disease Eligible for Deep Brain Stimulation
Objective: To characterize glymphatic- and cerebrospinal fluid (CSF)-related imaging alterations in moderate-to-advanced, deep brain stimulation (DBS)-eligible Parkinson’s disease (PD) using a multidimensional magnetic resonance imaging (MRI) framework. Methods: We studied 60 moderate-to-advanced…
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Journal Article
Relationship between neurotic personality and depression: mediating effects of maladaptive emotion regulation strategies and anxiety
Introduction: Depression is a prevalent psychological problem among higher vocational college students. This study aimed to explore the potential relationships among neurotic personality, maladaptive emotion regulation strategies, anxiety, and depressive symptoms in higher vocational college…
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Journal Article
Nutritional Modulation of Cognitive Function and Brain Networks: A Comprehensive Review
Large-scale brain networks and neuroplastic processes support cognitive function across the lifespan and may be influenced by nutrition. This review integrates evidence from epidemiological studies, randomized dietary interventions, molecular neuroscience, and multimodal neuroimaging to examine the…
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Journal Article
Artificial Intelligence-Based Differentiation of Ischemic and Hemorrhagic Stroke: A Retrospective, Analytical and Observational Case-Control Design
Background: Rapid differentiation between ischemic and hemorrhagic stroke is essential because management differs significantly. In settings without immediate neuroimaging, artificial intelligence (AI) may assist early decision-making. To evaluate the performance of AI in distinguishing ischemic…
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Journal Article
Perineuronal Nets in Neuropsychiatric Disorders
Perineuronal nets (PNNs) are specialized extracellular matrix structures that enwrap select neuronal populations—particularly, parvalbumin-positive inhibitory interneurons. Under physiological conditions, they stabilize synaptic connectivity, regulate excitatory– inhibitory balance, and contribute…
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Journal Article
Alcohol and Headache: an Update
This update aimed to assess whether recent studies offer confirmation or new insights into the debated relationship between alcoholic drinks (AD) and migraine. Reported discrepancies in alcohol consumption and its triggering role across primary headache types may reflect methodological differences…
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Journal Article
The Biophysical Limits of Structural-Functional Connectivity Correlation in Neuroimaging Psychiatry
Correlation between structural connectivity (SC) from diffusion MRI and functional connectivity (FC) from fMRI is widely used in neuroimaging psychiatry as a measure of structure-function coupling (SFC) and is often taken as evidence of tight coupling between anatomy and neural communication. This…
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Journal Article
An overview of cohort studies in brain science research
Driven by the development of evidence-based medicine, cohort studies provide reliable and scientific evidence for brain health and neurological disorders. This review provides a concise introduction to several internationally renowned classical cohorts, highlighting their notable contributions to…