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Infectious Diseases & Immunity
Scopus
ISSN 2096-9511 · Wolters Kluwer Health - Lippincott Williams Wilkins · 197 articles in the index
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Journal Article
Invasive fungal disease in patients with end-stage liver disease
Abstract. Invasive fungal disease (IFD) has become a critical complication in patients with end-stage liver disease (ESLD), marked by a rising prevalence and the emergence of drug-resistant strains in recent decades. The heightened susceptibility to IFD in ESLD stems from liver-related immune…
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Journal Article
Tsukamurella pulmonis bacteremia in a young patient with epidermolysis bullosa: A case report
Abstract. Tsukamurella species are rare, aerobic, gram-positive actinomycetes that are increasingly recognized as opportunistic pathogens affecting immunocompromised patients, such as those suffering from epidermolysis bullosa. Epidermolysis bullosa is a rare genetic disorder characterized by skin…
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Journal Article
Younger age predicts increased HBsAg loss in children with chronic hepatitis B on antiviral therapy: A systematic review and meta-analysis
Abstract. Background:. Increasing evidence has suggested that the early initiation of antiviral treatment promotes better treatment responses in young children with chronic hepatitis B (CHB), including functional cure. But there are limited studies regarding the clinical responses of antiviral…
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Journal Article
A hidden culprit: Unusual thyroid involvement in melioidosis—A case report
Abstract. Melioidosis, caused by Burkholderia pseudomallei, is a serious infection with a wide range of clinical presentations; however, thyroid gland involvement is exceptionally rare.We present the case of a 56-year-old woman with poorly controlled diabetes who developed painful anterior neck…
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Journal Article
Global, regional, and national burden of pertussis in children aged 0–14 years from 1990 to 2021: A systematic analysis of the Global Burden of Disease Study 2021
Abstract. Background:. Despite widespread vaccination efforts, pertussis remains a significant global public health concern, particularly among children. This study aimed to assess the burden and temporal trends of pertussis globally, regionally, and nationally by age, sex, and socio-demographic…
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Journal Article
Characteristics, management, and outcomes of early symptomatic congenital syphilis in infants at a tertiary specialist hospital in Beijing from 2008 to 2024
Abstract. Background:. The neonate and infant periods are critical time windows for diagnosing and treating congenital syphilis (CS) so as to prevent its adverse outcomes. In order to assist pediatricians in achieving early diagnoses and to standardize evaluations and treatments of early CS, this…
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Journal Article
Functional cure for chronic hepatitis B: A state of immune control over cccDNA persistence
Abstract. Functional (clinical) cure is considered a desirable therapeutic endpoint of antiviral therapy for chronic hepatitis B (CHB). Recent studies have detected transcriptionally active covalently closed circular DNA (cccDNA) and integrated hepatitis B virus (HBV) DNA (iDNA) in the liver tissue…
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Journal Article
Single-cell profiling reveals immunometabolic remodeling with T-cell dysfunction in HIV-1 infected people
Abstract. Background:. Immunometabolism plays a vital role in the immunopathogenesis of people living with human immunodeficiency virus type 1 (HIV-1) (PLWH). However, the precise relationship between metabolic profiles and T-cell dysfunction in this population remains unclear. This study aimed to…
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Journal Article
Expert consensus on the clinical management of HIV late presentation
Abstract. With the advancement of combination antiretroviral therapy (cART), the global number of new human immunodeficiency virus (HIV) infections and HIV-related mortality has significantly declined. However, the high proportion of “late presentation” (defined as presenting to care with a low CD4…
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Journal Article
Mapping cellular signaling pathways involved in SARS-CoV-2 spike protein-mediated syncytia formation
Abstract. Background:. Severe coronavirus disease 2019 is associated with extensive syncytia formation, a process driven by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein-mediated cell–cell fusion in infected pneumocytes. This study aims to identify compounds to…
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Journal Article
Scrub typhus triggering seizure in a patient with a preexisting seizure disorder: A case report
Abstract. Scrub typhus is a bacterial infection caused by Orientia tsutsugamushi and transmitted by chigger bites. It presents as an acute febrile illness and can lead to serious complications, including liver and kidney dysfunction. Although neurological involvement is rare, cases have been…
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Journal Article
Geospatial epidemiological approaches to the prevention and control of vector-borne diseases: A systematic review
Abstract. Vector-borne diseases (VBDs), primarily transmitted through the bites of vectors such as mosquitoes, ticks, and sandflies, have been recognized as a critical global public health priority. This systematic review summarizes the pivotal role of geospatial technologies, including geographic…
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Journal Article
Emerging zoonotic threats: HKU5-CoV-2 and the CBRNE approach to pandemic prevention
Abstract. The emergence of HKU5-CoV-2, a novel lineage in the Merbecovirus subgenus, represents a potential zoonotic threat with significant implications for global health. This bat-derived virus, which is phylogenetically similar to the Middle East respiratory syndrome coronavirus and severe acute…
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Journal Article
Integrating national evidence with global standards: China’s updated dengue and chikungunya diagnosis and treatment plans
Abstract. China released updated national plans for dengue (2024) and chikungunya (2025) to standardize clinical management amid expanding Aedes-borne risk, recurrent importations with episodic local amplification, and heterogeneous diagnostic capacity. This article synthesizes the clinical and…
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Journal Article
Progress in research on mosquito-borne viruses: Understanding infection, transmission, and control
Abstract. Mosquito-borne viruses (MBVs) are a group of arboviruses belonging to diverse families and genera. Transmitted through mosquito bites, MBVs are a significant public health concern. These pathogens can cause a spectrum of mosquito-borne viral diseases (MBVDs) ranging from rashes, mild…