310 results

Role of thymus on prognosis of myasthenia gravis in Turkish population

Hulya Tireli; Gülbün Asuman Yüksel; Tamer Okay et al.

İstanbul Kuzey Klinikleri, Vol. 7 No. 5 · 2020 · English · DOAJ Scopus

OBJECTIVE: Myasthenia gravis (MG) is an autoimmune disease that may cause a disorder in transmission at the neuromuscular junction. Antibodies directed against acetylcholine receptors are responsible. The thymus is the place that that production of these antibodies mainly occurs. The thymus gland…

The urine foaming test in COVID-19 as a useful tool in diagnosis, prognosis and follow-up: Preliminary results

Mehmet Serhan Kurtulmus; Cemal Kazezoglu; Busra Cakiroglu et al.

İstanbul Kuzey Klinikleri, Vol. 7 No. 6 · 2020 · English · DOAJ Scopus

OBJECTIVE: We aimed to develop a simple, rapid urine test based on the level of foaming that occurs in the urine sample due to the excretion of peptide structures containing amino acids specific to the antigenic structure of COVID-19. In this study, we present the preliminary results of the first…

Factors affecting survival in operated pancreatic cancer: Does tumor localization have a significant effect on treatment outcomes?

Abdullah Sakin; Suleyman Sahin; Ayşegül Sakin et al.

İstanbul Kuzey Klinikleri, Vol. 7 No. 5 · 2020 · English · DOAJ Scopus

OBJECTIVE: This study aims to investigate the factors affecting survival in operated pancreatic ductal adenocarcinoma (PDAC) and the possible prognostic effect of primary tumor localization on treatment outcomes. METHODS: In this study, 98 patients with curatively-operated PDAC, who were followed…

The origin of SARS-CoV-2 in Istanbul: Sequencing findings from the epicenter of the pandemic in Turkey

İlker Karacan; Tuğba Kızılboğa Akgün; Nihat Buğra Ağaoğlu et al.

İstanbul Kuzey Klinikleri, Vol. 7 No. 3 · 2020 · English · DOAJ Scopus

OBJECTIVE: Turkey is one of the latest countries that COVID-19 disease was reported, with the first case on March 11, 2020, and since then, Istanbul became the epicenter of the pandemic in Turkey. Here, we reveal sequences of the virus isolated from three different patients with various clinical…

The relationship between personality traits and BMI categories

Emrah Tekin; Can Öner; Hüseyin Çetin et al.

İstanbul Kuzey Klinikleri, Vol. 7 No. 4 · 2020 · English · DOAJ Scopus

OBJECTIVE: To compare personality traits between average weight, overweight and obese people using Eysenck Personality Questionnaire Revised-Abbreviated Form (EPQR-A). Study design: Cross-sectional, descriptive study. Place and duration of study: S. B. U Kartal Dr. Lutfi Kirdar Training and…

Assessment of the relationship between patellar volume and chondromalacia patellae using knee magnetic resonance imaging

Mehmet Sirik; Abuzer Uludag

İstanbul Kuzey Klinikleri, Vol. 7 No. 3 · 2020 · English · DOAJ Scopus

OBJECTIVE: In this study, we evaluated the relationship between patellar volume and chondromalacia patellae. METHODS: A total of 162 patients who underwent knee magnetic resonance imaging (MR) due to knee pain at our department between January 2017 and May 2017 were included in this study. Of the…

Assessment of a new electrocardiographic criterion for the diagnosis of left ventricle hypertrophy: A prospective validation study

Kudret Keskin; Özgür Selim Ser; Güneş Melike Doğan et al.

İstanbul Kuzey Klinikleri, Vol. 7 No. 3 · 2020 · English · DOAJ Scopus

OBJECTIVE: Many criteria have been developed to predict left ventricular hypertrophy using an electrocardiogram (ECG). However, one major common limitation of all has been their low sensitivity. Based on that, recently, a novel criterion has been proposed, which is believed to have higher…

Incarcerated Spigelian hernia: A rare cause of abdominal wall tender mass

Ender Anilir; Fatih Buyuker; Salih Tosun et al.

İstanbul Kuzey Klinikleri, Vol. 7 No. 1 · 2020 · English · DOAJ Scopus

In this study, we aimed to present that incarcerated Spigelian hernia is an important cause of acute abdomen although it is rare and accounts for 1–2% of all abdominal wall hernias. Spigelian hernia arises from a defect in the aponeurosis of the transversus abdominis muscle, also known as the…

Can the development of atrial fibrillation in patients with ischemic heart failure with low ejection fraction be predicted?

Seref Alpsoy; Kubilay Erselcan; Aydın Akyüz et al.

İstanbul Kuzey Klinikleri, Vol. 7 No. 1 · 2020 · English · DOAJ Scopus

OBJECTIVE: Our aim is to determine the triggering factors of paroxysmal atrial fibrillation (PAF) in ischemic heart failure (HF) patients with low ejection fraction (EF). METHODS: Sixty patients were included in this study. Echocardiography and 24-hours Holter monitoring were performed after…

Detection of human immunodeficiency virus (HIV) RNA in the sweat of HIV-infected patients

Fatih Mehmet Hanege; Fatma Sargin; Servet Karaca et al.

İstanbul Kuzey Klinikleri, Vol. 7 No. 1 · 2020 · English · DOAJ Scopus

OBJECTIVE: Human immunodeficiency virus (HIV) infection is a significant health problem. Many studies reported that HIV was mainly transmitted through parenteral exposure, sexual activity, and body secretions, such as saliva and semen. Many people, including health-care providers and patient…

Dermoscopy of stage llA mycosis fungoides

Melike Kibar; Ilkin Zindanci; Ebru Zemheri

İstanbul Kuzey Klinikleri, Vol. 7 No. 2 · 2020 · English · DOAJ Scopus

OBJECTIVE: Differential diagnosis of mycosis fungoides (MF) in the early stages can be challenging. Dermoscopy has been reported to be useful in the evaluation of early MF. However, to our knowledge, there is no study that specifies these early stages as stage IA, IB or IIA. The present study aims…

Associated clinical abnormalities among patients with Turner syndrome

Suna Kılınç; Metin Yildiz; Ayla Guven

İstanbul Kuzey Klinikleri, Vol. 7 No. 3 · 2020 · English · DOAJ Scopus

OBJECTIVE: The early diagnosis of Turner syndrome (TS) is often difficult because of the various clinical features. This study aimed to investigate clinical features and identify associated abnormalities in a group of patients with TS. METHODS: Retrospective data of presenting clinical features…

The simple and fast swallowing function assessment in acute stroke patients

Taşkin Güneş; Esengül Liman Yazıcı; İrem Baş et al.

İstanbul Kuzey Klinikleri, Vol. 7 No. 4 · 2020 · English · DOAJ Scopus

OBJECTIVE: The dysphagia associated pulmonary aspiration is one of the important reasons for mortality and morbidity in stroke. In this study, we evaluated the early swallowing functions of the acute ischemic stroke patients, and tried to choose the right way to start feeding with simple tests…

Responding to COVID-19 in Istanbul: Perspective from genomic laboratory

Levent Doganay; Nihat Bugra Agaoglu; Arzu Irvem et al.

İstanbul Kuzey Klinikleri, Vol. 7 No. 3 · 2020 · English · DOAJ Scopus

NCI-2020-0130

The magnetic resonance neurography of a Parsonage-Turner syndrome case

Selcuk Sayilir; Nesat Cullu; Timur Ekiz

İstanbul Kuzey Klinikleri, Vol. 7 No. 1 · 2020 · English · DOAJ Scopus

Corticosteroid-resistant anakinra-responsive protracted febrile myalgia syndrome as the first manifestation of familial Mediterranean fever

Mustafa Çakan; Şerife Gül Karadağ; Nuray Aktay Ayaz

İstanbul Kuzey Klinikleri, Vol. 7 No. 1 · 2020 · English · DOAJ Scopus

Familial Mediterranean fever (FMF) is the most common type of monogenic periodic fever syndromes and characterized by recurrent self-limited attacks of fever and polyserositis. Musculoskeletal signs and symptoms are not uncommon and manifested as arthritis and myalgia. Myalgia may be spontaneous or…

Pediatric coronavirus disease 2019 (COVID-19): An insight from west of Iran

Jafar Soltani; Iraj Sedighi; Zohreh Shalchi et al.

İstanbul Kuzey Klinikleri, Vol. 7 No. 3 · 2020 · English · DOAJ Scopus

OBJECTIVE: To study the clinical, laboratory, and radiological characteristics of the pediatric patients infected with the new emerging 2019 coronavirus virus (SARS-CoV-2) in Hamadan and Sanandaj, west of Iran. METHODS: A descriptive study was conducted in Hamadan and Kurdistan province between…

Telecardiographic measurements for device migration: A useful tool for follow-up

Fatih Avni Bayraktar; Muge Tasdemir Mete; Murat Sargin et al.

İstanbul Kuzey Klinikleri, Vol. 7 No. 2 · 2020 · English · DOAJ Scopus

OBJECTIVE: Pump thrombosis in left ventricular assist device (LVAD) patients is an important cause of mortality and morbidity. Inflow cannula migration is a predisposing factor for pump thrombosis. Telecardiographic measurements can be used to follow up apical cannula deviation. In this study, we…

Comparison of success between external and endonasal dacryocystorhinostomy in primary acquired nasolacrimal duct obstruction in Turkish cohort

Bugra Karasu; Gulunay Kiray; Erdem Eris et al.

İstanbul Kuzey Klinikleri, Vol. 7 No. 6 · 2020 · English · DOAJ Scopus

OBJECTIVE: To evaluate the results and recurrence rates of external and endonasal dacryocystorhinostomy (DCR) surgery in patients with primary acquired nasolacrimal duct obstruction (PANDO) in Turkish Cohort. METHODS: Medical records were reviewed in all patients who underwent surgery for PANDO…

The effects of sacubitril/valsartan and ramipril on the male fertility in hypertensive rats

Duygun Altıntaş Aykan; Asli Yaylali; Nadire Eser et al.

İstanbul Kuzey Klinikleri, Vol. 7 No. 5 · 2020 · English · DOAJ Scopus

OBJECTIVE: Renin angiotensinogen system (RAS) inhibitors, ramipril and sacubitril/valsartan are frequently used in the treatment of cardiovascular diseases. Although they are known as contraindicated during pregnancy in hypertensive women, there is not any outcome of their safety in male fertility…