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Journal of the Turkish Chemical Society, Section A: Chemistry
Scopus
ISSN 2149-0120 · Turkish Chemical Society · 823 artikel di indeks
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Artikel Jurnal
Natural Metabolites from Clinacanthus nutans as Promising SARS-CoV-2 Main Protease Inhibitors: Insights from Molecular Docking and Dynamics Simulations
Structure-based drug design against SARS-CoV-2 main protease (Mpro) was enabled by the availability of its crystal structure (PDB ID: 6LU7). In this study, metabolites from Clinacanthus nutans were computationally evaluated as potential Mpro inhibitors using validated molecular docking and…
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Artikel Jurnal
Comparative Evaluation of Antioxidant, Phenolic, Flavonoid, Protein, And Isoflavone Profiles in Commercial Soy Products: A Multi-Methodological Approach
Soybeans are recognized for their high-quality protein, antioxidant activity, and bioactive phytochemicals. This study evaluated five commercial soy products–soy milk, soy cheese, soy flour, soy ground meat, and soybean sprouts–using spectrophotometric assays (CUPRAC, ABTS, Folin-Ciocalteu…
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Artikel Jurnal
Physical Properties Enhancement of Bitumen via Hybrid Modification Using Cellulose and Glass Powder
This study investigates the effects of hybrid modification with cellulose fibers and glass powder on the physical and rheological properties of paving-grade bitumen. Various concentrations of cellulose (1%, 3%, 5%, 7%, and 10%) and glass powder (3% and 5%) were incorporated individually and in…
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Artikel Jurnal
Synthesis, DFT Evaluation, and Docking-Based Assessment of Novel Substituted Pyridine Derivatives against Human Spermine Oxidase
This study combines structure-based molecular docking simulations and DFT calculations to investigate interactions between the crystal structure of human Spermine Oxidase (SMOX) and a series of three novel 2,4,6-substituted pyridine compounds as docking-prioritized SMOX-interacting candidates. The…
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Artikel Jurnal
Triphenylamine-based turn-on fluorescent probe for selective and sensitive detection of bisulfite/sulfite
A triphenylamine-based turn-on fluorescent probe has been developed for the highly selective and sensitive detection of bisulfite (HSO₃⁻)/sulfite(SO₃2⁻) ions in aqueous media. Upon reaction with HSO₃⁻/SO₃2⁻, the probe undergoes a specific chemical transformation via aldehyde functionality…
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Artikel Jurnal
Glycoprotein Levels in Rats with Ethanol-Induced Kidney and Small Intestine Injury: Protective Effects of Cotinus coggygria Scop.
Alcohol use disorder is a significant public health problem that is widespread worldwide and causes serious health issues. During ethanol metabolism, acetaldehyde accumulation and free radical formation increase, causing various tissue damage through oxidative stress. The Cotinus coggygria Scop…
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Artikel Jurnal
Phase behavior in Cu₈SiS₆-Ag₈SiS₆ and Cu₈SiSe₆-Ag₈SiSe₆ systems and new cubic argyrodyte phases with variable composition
Argyrodite-family compounds and their derivative phases are environmentally friendly functional materials with a wide range of valuable properties, including thermoelectric, photoelectric, and optical properties, as well as high ionic conductivity arising from the high mobility of Cu⁺ and Ag⁺ ions…
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Artikel Jurnal
Effect of Terminal Donor Units on the Electronic and Photovoltaic Properties of Conjugated Small Molecules: A DFT/TD-DFT Study
Isoindigo-based donor–acceptor small molecules are promising candidates for organic photovoltaic applications because of their strong electron-accepting character and tunable π-conjugated structures. In this work, seven isoindigo-based derivatives bearing phenyl, thiophene, thiophene…
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Artikel Jurnal
Synthesis, Antibacterial, Antioxidant, and In Silico Evaluation of New Sulfamethoxazole-Based Schiff Base and Azo Derivatives
This research involved the preparation of a new Schiff base derivative (1) and azo derivatives (2–7) based on sulfamethoxazole through the coupling reaction of diazonium salt with various phenols. The yields were very high, ranging from 81% to 91%. The synthesis of these compounds was characterized…
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Artikel Jurnal
Nano-Fe2O3 Assisted Torrefaction of Pine Wood Waste: Structural Characterization, Thermal Stability, and Gaseous Hydrocarbon Analysis
The effect of nano-Fe2O3 on the structural transformation, thermal behavior, product distribution, and gas-phase hydrocarbon composition of pine wood waste during torrefaction was investigated. Torrefaction experiments were performed in a fixed-bed tubular reactor at 300 °C for 5 min under a…
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Artikel Jurnal
Investigation of The Utilization of Alginate/Chitosan Nanoparticles for Tamoxifen Delivery
In this work, the usability of tamoxifen-loaded alginate/chitosan nanoparticles as a drug release system was investigated. Optimal conditions for nanoparticle preparation were determined, and the nanoparticles were characterized using Fourier transform infrared spectroscopy (FTIR), atomic force…
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Artikel Jurnal
Removal of Cu(II), Ni(II), and Cd(II) Ions from Aqueous Media using Glycidyl Methacrylate-Grafted Poly(ethylene terephthalate) Fibers Functionalized with Hydroxyl Amine
In this study, poly(ethylene terephthalate) (PET) fiber was treated with glycidyl methacrylate (GMA) using benzoyl peroxide (Bz2O2) to start the reaction in water (GMA-g-PET). Then, hydroxylamine (HA) was chemically attached to the GMA-treated PET fiber (HA-GMA-g-PET). The results indicated that a…
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Artikel Jurnal
Green Design and Theoretical Validation of A Novel Anthraquinone-Based Silica Sorbent for Selective Extraction of Pb(II) and Cd(II) from Brackish Aquaculture Water
In this study, a novel silica-supported sorbent functionalized with 1,4-bis[(4-methoxybenzyl) oxy]anthracene-9,10-dione was prepared and applied for the first time for the selective adsorption and preconcentration of Pb(II) and Cd(II) ions from brackish aquaculture water. The sorbent was…
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Artikel Jurnal
Novel Mannich Base Complexes of 5-Chloro-1,3-benzoxazole-2(3H)-thione as Antioxidant and Anticancer Agents
A new ligand of Mannich base (5-chloro-3-(dibenzyl amino) (phenyl)methyl) benzo[d]oxazole-2(3H)-thione) (L1) was synthesized. Micro complexes (CuL1) and (ZnL1) were synthesized, and their anti-tumor and antioxidant activity against cancer cells (MCF-7) were investigated. The derivative (L1) has…
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Artikel Jurnal
Investigating the Effects of Carbonate Additives on Zn-Air Battery
Alkaline zinc-air batteries (ZABs) exhibit high theoretical energy density and capacity, along with intrinsic safety and cost-effectiveness. However, the widespread adoption of ZABs is hindered by various challenges, including the vigorous hydrogen evolution reaction (HER) and zinc dendrite…
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Artikel Jurnal
Computational and Experimental Evaluation of Azadirachta indica Leaf Extract Against Streptococcus pneumoniae and Streptococcus pyogenes
The rise of antibiotic resistance in pneumonia therapy highlights the urgent need for alternative treatments derived from natural sources. Azadirachta indica leaves contain diverse secondary metabolites with notable antibacterial potential, yet their effects on Streptococcus pneumoniae and…
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Artikel Jurnal
Physicochemical Parameters Affecting Lipase Performance: Including New Methods and Techniques Increasing Lipase Activity
Lipases are versatile green biocatalysts from the hydrolase family, valued for their high selectivity, specificity, and catalytic efficiency in diverse industrial applications, including pharmaceuticals, food, and bioenergy. Their activity and productivity are strongly influenced by a range of…
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Artikel Jurnal
Spectrophotometric Method for the Determination of Bromhexine-HCl in Bulk and Dosage Forms Via Azo Dye Formation with 4'-Chloro-4-Hydroxychalcone
Bromhexine-HCl (BHH) can be determined in pharmaceutical formulations and in its pure form using a simple, quick, and affordable spectrophotometric approach. New organic reagents are prepared for the investigation, and 4'-Chloro-4-hydroxychalcone (4-CHC) is chosen as the best reagent. A second…
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Artikel Jurnal
Synthesis of Dithizone (DHZ) Derivative and Its Use as Ionophore in the Potentiometric Determination of Pb²⁺ Ions
In this study, a dithizone (Di-DHZ) derivative was synthesized, characterized by UV-Vis analysis, used as an ionophore in a potentiometric sensor, and selectively used in Pb2+ ion detection. Di-DHZ compound was synthesized by the reaction of dithizone and iodine in dichloromethane. In UV analyses…
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Artikel Jurnal
Enhanced PEG Performance via Functionalized MWCNTs Reinforcement: A Chemical and Thermal Perspective
This study examines the structural, thermal, and morphological characteristics of polyethylene glycol (PEG) reinforced with functionalized multi-walled carbon nanotubes (F-MWCNTs) at various concentrations (0.5–1.5 wt.%). FTIR analysis verified successful incorporation and interfacial interactions…