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Cyprus Journal of Medical Sciences
ISSN 2149-7893 · Galenos Publishing House · 138 articles in the index
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Journal Article
Dual-Focused Type I Heterotopic Pancreas in the Gastric Antrum: A Rare Case with Clinical-Anatomical Implications
Heterotopic pancreas (HP) is a rare congenital anomaly defined by pancreatic tissue outside the normal anatomical pancreas without ductal or vascular continuity. Although frequently asymptomatic, lesions located in the gastric antrum may produce dyspeptic symptoms and delayed gastric emptying…
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Journal Article
Hematological Parameters and Inflammation in Primary Headache Types: A Retrospective Study of Migraine and Chronic Tension-Type Headache
BACKGROUND/AIMS: Headache disorders, particularly migraine and chronic tension-type headache (CTTH), are highly prevalent neurological conditions contributing substantially to global disability. Hematologic and inflammatory markers have been proposed as potential indicators of migraine, yet…
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Journal Article
Serum IL-27 and IL-35 Levels as Complementary Biomarkers of Immune Status in HIV-Positive Individuals
BACKGROUND/AIMS: Human immunodeficiency virus (HIV) infection remains a worldwide public health challenge, primarily due to its disruption of immune regulation and cytokine homeostasis. As members of the interleukin (IL)-12 family, IL-27 and IL-35 contribute to immune regulation, although they may…
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Journal Article
Obesity and Obesity-Related Hypertension in Northern Cyprus: Findings from a Population-Based Cross-Sectional Study
BACKGROUND/AIMS: Obesity constitutes a chronic and multifactorial condition characterized by an excessive accumulation of adipose tissue and is linked to a wide range of comorbidities, including hypertension (HT). Its predominant cause is the disparity between caloric intake and the body’s energy…
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Journal Article
Comparison of Performance Parameters of Professional Football Players with Unilateral Anterior Cruciate Ligament Reconstruction to the Contralateral Extremity
BACKGROUND/AIMS: Anterior cruciate ligament (ACL) injury and reconstruction can lead to persistent neuromuscular deficits and impaired athletic performance. However, the extent of inter-limb asymmetry in professional football players after unilateral ACL reconstruction (ACLR) remains unclear. This…
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Journal Article
Evaluation of Combined Surgical and Antibiotic Treatment Outcomes in Diabetic Foot Ulcers: A Retrospective Cohort Study
BACKGROUND/AIMS: Diabetes is a global health challenge with a growing prevalence, affecting millions worldwide. Diabetic foot ulcer (DFU) is among its severe complications and significantly contributes to morbidity, particularly in regions with high prevalence, such as Palestine. Despite the high…
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Journal Article
Calcium Supplementation and Bone Health - Baseline Network Analysis of Anthropometric, Biochemical, Dietary, and Bone Health Variables in Adolescent Girls: A Foundational Assessment Prior to Nutritional Intervention
BACKGROUND/AIMS: Adolescence is a sensitive phase of skeletal and metabolic growth. Elucidation of the interlinkages between physiological and nutritional factors can guide specific interventions for enhancing bone health and overall well-being. The main objective of this study was to analyze…
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Journal Article
Comparative Analysis of Cell Dilution Assays for Single-Cell Colony Formation in CRISPR-Mediated Knockout Screening
BACKGROUND/AIMS: The ribonucleic acid (RNA)-guided Cas9 nuclease from the microbial clustered regularly interspaced palindromic repeats (CRISPR) immune system enables genome editing in eukaryotic cells by using a 20-nucleotide target sequence guide RNA. A key CRISPR technique is the ability to…
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Journal Article
Association of ADIPOQ Gene Variants and Circulating Adiponectin Levels with Coronary Artery Disease Risk
BACKGROUND/AIMSCoronary artery disease (CAD) is a major international health issue, closely linked with obesity and its associated metabolic complications. Adiponectin, an adipokine involved in glucose and lipid metabolism, might contribute to the development of CAD. This study investigated the…
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Journal Article
Bibliometric Analysis of Research on Premature Adrenarche from 1974 to 2024
BACKGROUND/AIMS: Premature adrenarche (PA) is a clinical condition marked by early activation of adrenal androgens prior to puberty. Once regarded as a benign developmental variant, PA is now linked to long-term health risks such as metabolic syndrome, polycystic ovary syndrome (PCOS), and type 2…
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Journal Article
Glycemic Control and Associated Factors Among Adult Type Two Diabetic Patients in Selected Hospitals, Addis Ababa, Ethiopia
BACKGROUND/AIMS: Diabetes mellitus (DM) is a chronic metabolic disease characterized by elevated blood glucose levels and affects 3.8 percent of the Ethiopian population, according to the American Diabetes Association’s recommendations. To prevent long-term diabetes-related complications, people…
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Journal Article
Neuroanatomical Correlates of Auditory Hallucinations in Schizophrenia: A Structural MRI Morphometry Study
BACKGROUND/AIMS: Schizophrenia is a complex neuropsychiatric disorder marked by diverse structural brain abnormalities and clinical heterogeneity. Auditory verbal hallucinations (AVH), a hallmark symptom of the disorder, are thought to involve disruptions in limbic, paralimbic, and cortical…
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Journal Article
Unmasking Candidozyma auris: Whole Genome Sequencing-Driven Discoveries in Pathogenesis and Treatment Innovation
Candidozyma auris (formerly known as Candida auris, C.auris) is a pathogenic yeast that can cause invasive candidiasis and hospital outbreaks. It is considered an emerging global health issue due to its high mortality, high transmissibility, resistance to extreme environmental conditions, and…
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Journal Article
Rare Isolated Bladder Metastasis in Breast Cancer
Breast cancer (BC) is the most common cancer in women, and approximately 317,000 new cases are expected to be diagnosed in the United States in 2025. Lymph nodes, bones, lungs, liver, and brain are common target organs for BC metastasis. Metastasis to the bladder is extremely rare, with…
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Journal Article
Kleefstra Syndrome-2 Case with a Novel Mutation and Multiple Disorders
Kleefstra syndrome-2 (KLEFS2) is an extremely rare autosomal dominant condition characterized by a neurodevelopmental disorder and multisystem involvement. The main clinical manifestations include intellectual disability, autistic features, hypotonia, and dysmorphic facial features. We describe a…
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Journal Article
Adjunctive Multimodal Therapy Incorporating Iontophoresis-Assisted Growth Factor Delivery for Hair Loss: A Real-World Retrospective Study
BACKGROUND/AIMS: Adjunctive multimodal therapies incorporating iontophoresis-assisted growth factor delivery have emerged as potential non-invasive treatment options for hair loss; however, real-world clinical evidence remains limited. This study evaluated the feasibility, tolerability…
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Journal Article
Systemic Inflammatory Response Index and Systemic Immune-Inflammation Index in Parkinson’s Disease
BACKGROUND/AIMS: Peripheral immune activity may contribute to Parkinson’s disease (PD), but the clinical usefulness of blood cell-derived composite indices is not established. We compared the systemic immune-inflammation index (SII) and systemic inflammatory response index (SIRI) between patients…
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Journal Article
Blood Urea Nitrogen to Albumin Ratio in Acute Pancreatitis: A Potential Supportive Marker for Early Triage between Ward and Intensive Care
BACKGROUND/AIMS: This study aimed to evaluate the prognostic significance of the blood urea nitrogen (BUN) to albumin ratio (BAR) in patients with acute pancreatitis (AP) by comparing the clinical, biochemical, and hematological profiles of patients directly admitted to the ward and the intensive…
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Journal Article
Evaluation of the C-Reactive Protein to HDL Cholesterol Ratio as a Marker of Cardiovascular and Renal Risk Among Type 2 Diabetic Patients
BACKGROUND/AIMS: Type 2 diabetes (T2D) is a metabolic disorder commonly accompanied by persistent low-grade inflammation, accelerated development of atherosclerosis, and gradual decline in renal function. The ratio of C-reactive protein (CRP) to high-density lipoprotein-cholesterol (HDL-C) has…
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Journal Article
Seroprevalence Trends of HBV, HCV, and HIV Before and During the COVID-19 Pandemic: Five-Year Retrospective Data from a Tertiary Hospital in Northern Cyprus
BACKGROUND/AIMS: To assess five-year seroreactivity trends of hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV) in Northern Cyprus, with emphasis on the coronavirus disease 2019 (COVID-19) and post-pandemic periods. MATERIALS AND METHODS: This retrospective…