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G3: Genes, Genomes, Genetics
Scopus
ISSN 2160-1836 · Oxford University Press · 2,428 articles in the index
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Journal Article
Mediator subunit MDT-15 promotes expression of propionic acid breakdown genes to prevent embryonic lethality in Caenorhabditis elegans
AbstractThe micronutrient vitamin B12 is an essential cofactor for two enzymes: methionine synthase, which plays a key role in the one-carbon cycle; and methylmalonyl-CoA mutase, an enzyme in a pathway that breaks down branched-chain amino acids and odd-chain fatty acids. A second, vitamin…
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Journal Article
An annotated chromosome-scale reference genome for Eastern black-eared wheatear (Oenanthe melanoleuca)
AbstractPervasive convergent evolution and in part high incidences of hybridization distinguish wheatears (songbirds of the genus OenantheOenanthe melanoleucaOenanthe hispanica
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Journal Article
smalldisco, a pipeline for siRNA discovery and 3′ tail identification
AbstractCapturing and sequencing small RNAs is standard practice; however, identification of a group of these small RNAs—small interfering RNAs (siRNAs)—has been more difficult. We present smalldisco, a command-line tool for…
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Journal Article
A high-quality, long-read genome assembly of the whitelined sphinx moth (Lepidoptera: Sphingidae: Hyles lineata) shows highly conserved melanin synthesis pathway genes
AbstractThe sphinx moth genus HylesHyles lineataHyles lineataH. lineataManduca sexta
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Journal Article
Ovarian transcriptional response to Wolbachia infection in D. melanogaster in the context of between-genotype variation in gene expression
Abstract WolbachiaWolbachiaWolbachiaWolbachiaDrosophila melanogasterD. melanogasterWolbachiaWolbachia
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Journal Article
Chromosome-scale genome assembly of the pink bollworm, Pectinophora gossypiella, a global pest of cotton
AbstractThe pink bollworm, Pectinophora gossypiellaBacillus thuringiensisP. gossypiella
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Journal Article
Experimental considerations for study of C. elegans lysosomal proteins
AbstractLysosomes are an important organelle required for the degradation of a range of cellular components. Lysosome function is critical for development and homeostasis as dysfunction can lead to inherited genetic disorders, cancer, and neurodegenerative and metabolic diseases. The acidic and…
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Journal Article
Impact of the acquired subgenome on the transcriptional landscape in Brettanomyces bruxellensis allopolyploids
AbstractGene expression variation can provide an overview of the changes in regulatory networks that underlie phenotypic diversity. Certain evolutionary trajectories such as polyploidization events can have an impact on the transcriptional landscape. Interestingly, the evolution of the yeast…
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Journal Article
A targeted genetic modifier screen in Drosophila uncovers vulnerabilities in a genetically complex model of colon cancer
AbstractReceived on 16 January 2023; accepted on 21 February 2023Kinases are key regulators of cellular signal transduction pathways. Many diseases, including cancer, are associated with global alterations in protein phosphorylation networks. As a result, kinases are frequent targets of drug…
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Journal Article
Transcriptomic analysis provides insight into the mechanism of IKKβ-mediated suppression of HPV18E6-induced cellular abnormalities
AbstractHigh-risk human papillomaviruses (HPVs) 16 and 18 are responsible for more than 70% of cervical cancers and majority of other HPV-associated cancers world-wide. Current treatments for these cancers have limited efficacy, which in turn has resulted in disease recurrence and poor survival…
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Journal Article
A high-quality reference genome for the fission yeast Schizosaccharomyces osmophilus
AbstractFission yeasts are an ancient group of fungal species that diverged from each other from tens to hundreds of million years ago. Among them is the preeminent model organism Schizosaccharomyces pombeS. pombeS. japonicusS. octosporusS. cryophilusS. osmophilusS. osmophilusS. octosporusS…
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Journal Article
Protein coding variation in the J:ARC and J:DO outbred laboratory mouse stocks provides a molecular basis for distinct research applications
AbstractOutbred laboratory mice (Mus musculus
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Journal Article
The genome of the oomycete Peronosclerospora sorghi, a cosmopolitan pathogen of maize and sorghum, is inflated with dispersed pseudogenes
AbstractSeveral species in the oomycete genus PeronosclerosporaPeronosclerosporaP. sorghiP. sorghiPeronospora effusaP. sorghiPeronosclerosporaPeronosclerospora
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Journal Article
Design and validation of a high-density single nucleotide polymorphism array for the Eastern oyster (Crassostrea virginica)
AbstractDense single nucleotide polymorphism (SNP) arrays are essential tools for rapid high-throughput genotyping for many genetic analyses, including genomic selection and high-resolution population genomic assessments. We present a high-density (200 K) SNP array developed for the Eastern oyster…
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Journal Article
The gyrfalcon (Falco rusticolus) genome
AbstractHigh-quality genome assemblies are characterized by high-sequence contiguity, completeness, and a low error rate, thus providing the basis for a wide array of studies focusing on natural species ecology, conservation, evolution, and population genomics. To provide this valuable resource for…
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Journal Article
The effect of Drosophila attP40 background on the glomerular organization of Or47b olfactory receptor neurons
AbstractBacteriophage integrase-directed insertion of transgenic constructs into specific genomic loci has been widely used by DrosophilaattP40attP40DrosophilaMsp300attP40ttP40Or47b-GAL4Msp300attP40attP40attP40
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Journal Article
Results from rapid-cycle recurrent genomic selection in spring bread wheat
AbstractGenomic selection (GS) in wheat breeding programs is of great interest for predicting the genotypic values of individuals, where both additive and nonadditive effects determine the final breeding value of lines. While several simulation studies have shown the efficiency of rapid-cycling GS…
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Journal Article
Draft genome assemblies of the avian louse Brueelia nebulosa and its associates using long-read sequencing from an individual specimen
AbstractSequencing high molecular weight (HMW) DNA with long-read and linked-read technologies has promoted a major increase in more complete genome sequences for nonmodel organisms. Sequencing approaches that rely on HMW DNA have been limited to larger organisms or pools of multiple individuals…
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Journal Article
Yield prediction through integration of genetic, environment, and management data through deep learning
AbstractAccurate prediction of the phenotypic outcomes produced by different combinations of genotypes, environments, and management interventions remains a key goal in biology with direct applications to agriculture, research, and conservation. The past decades have seen an expansion of new…
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Journal Article
No evidence for sex chromosomes in natural populations of the cichlid fish Astatotilapia burtoni
AbstractSex determination (SD) is not conserved among teleost fishes and can even differ between populations of the same species. Across the outstandingly species-rich fish family Cichlidae, more and more SD systems are being discovered. Still, the picture of SD evolution in this group is far from…
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