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Ophthalmology and Therapy
Scopus
ISSN 2193-8245 · Adis, Springer Healthcare · 1.008 artikel di indeks
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Artikel Jurnal
STudy of Atropine to Reduce (STAR) Myopia Progression in Children: 24-Month Results of a Randomized, Double-Masked, Vehicle-Controlled Trial of Atropine Sulfate 0.01% and 0.03%
Abstract Introduction Pediatric myopia is rising globally, with high myopia associated with sight-threatening complications later in life. Low-dose atropine has been shown to slow myopia progression, with most studies conducted in Asian populations using compounded formulations. We evaluated the…
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Artikel Jurnal
Long-Term Evolution of Treatment Outcomes with Once-Daily Ciclosporin A 0.1% Cationic Emulsion in Patients with Dry Eye Disease and Severe Keratitis
Abstract Introduction A 3-year multicenter trial was conducted to examine safety/tolerability and potential symptom relief delays following ocular sign improvement in patients with dry eye disease (DED) and severe keratitis using once-daily ciclosporin A (CsA) 0.1% cationic emulsion (CE). Methods…
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Perfluorohexyloctane Ophthalmic Solution in Patients with Dry Eye Disease Undergoing Cataract Surgery: A Prospective Multicenter Study
Abstract Introduction Dry eye disease (DED) is a common comorbidity in patients undergoing cataract surgery. Perfluorohexyloctane ophthalmic solution (PFHO) forms a protective layer on the tear film surface to reduce evaporation and is approved for treatment of signs and symptoms of DED. Because…
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Artikel Jurnal
Tele-Ophthalmology for Retinal Health Surveillance in Denmark
Abstract In this commentary paper, we discuss the potential of population health surveillance of retinal health in Denmark using optometrist-based opportunist retinal examination with tele-ophthalmology pathway. Using 12 months of data from 79 high-street optometrist stores, we imaged 355,818…
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Artikel Jurnal
Therapeutic Equivalence of Eyluxvi (Aflibercept) to Eylea in Neovascular Age-Related Macular Degeneration: ALTERA Trial (Randomized)
Abstract Introduction This study aimed to evaluate the efficacy and safety of Eyluxvi, an aflibercept biosimilar, compared with reference Eylea in patients with neovascular age-related macular degeneration (nAMD). Methods This phase 3, multicenter, randomized, double-masked, parallel-group study…
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Artikel Jurnal
Early Outcomes of Intravitreal Aflibercept 8 mg in Eyes Previously Treated with Aflibercept 2 mg for Neovascular Age-Related Macular Degeneration with AI-Based Biomarker Quantification
Abstract Introduction To evaluate the early outcomes of aflibercept 8 mg (afl8) treatment in patients with neovascular age-related macular degeneration (nAMD) previously treated with aflibercept 2 mg (afl2). Methods A retrospective, observational, monocentric Swiss study. Patients with nAMD who had…
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Artikel Jurnal
Prospective Pilot Study of Sustained Release Bimatoprost Implant with SpyGlass Intraocular Lens: 3-Year Results
Abstract Introduction This study aimed to explore the safety and efficacy of sustained release bimatoprost implant with SpyGlass intraocular lens (SpyGlass Pharma, Inc., Aliso Viejo, CA, USA). Methods Twenty-four subjects diagnosed with cataracts and mild-to-moderate primary open-angle glaucoma…
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Artikel Jurnal
Rapid Pathogen Detection in Severe Infectious Keratitis: Prospective Evaluation of Combined Multiplex PCR Panels Versus Standard Microbiology
Abstract Introduction Rapid pathogen identification in severe infectious keratitis is critical for targeted therapy to prevent vision loss, but conventional methods are slow and only moderately sensitive. Our objective was to evaluate the diagnostic accuracy and turnaround time of combined…
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Artikel Jurnal
Post-phacoemulsification Vascular Changes in the Macula and Optic Nerve Using Optical Coherence Tomography Angiography: A Systematic Review
Abstract Introduction Age-related cataracts are the leading cause of blindness worldwide, and phacoemulsification is the standard surgical treatment. Optical coherence tomography angiography (OCTA) enables non-invasive assessment of these microvascular changes. However, findings from individual…
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Artikel Jurnal
Budget Impact of Faricimab in Neovascular Age-Related Macular Degeneration in the Netherlands: A Systematic Review and Meta-Analysis of Injection Count
Abstract Introduction Frequent anti-vascular endothelial growth factor (anti-VEGF) injections for the treatment of neovascular age-related macular degeneration (nAMD) burden patients and healthcare systems. Faricimab may reduce this burden, but robust data are lacking. This study aimed to…
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Artikel Jurnal
Update on XEN Gel Stent: A Narrative Review on Indications, Surgical Technique, and Postoperative Management
Abstract Despite topical ocular hypotensive treatment and selective laser trabeculoplasty being the preferred first-line treatment modalities for lowering intraocular pressure, many patients require surgery for further controlling glaucoma progression. The XEN stent is a surgical device designed…
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Artikel Jurnal
Evaluating Systemic Immune-Inflammation Index and Mortality in Diabetic Retinopathy: A NHANES 2005–2018 Cohort Study
Abstract Introduction Diabetic retinopathy (DR) is a leading cause of preventable blindness and is linked to excess mortality. Systemic inflammation plays a central role in DR pathogenesis, and the systemic immune-inflammation index (SII) has emerged as a novel marker associated with adverse…
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Artikel Jurnal
A Phase III Randomized Trial Comparing Efficacy, Safety, and Immunogenicity of ZRC-3285 vs. Eylea® in Patients with Wet Age-Related Macular Degeneration
Abstract Introduction This study aims to evaluate the efficacy, safety, and immunogenicity of ZRC-3285 (aflibercept biosimilar) with Eylea® (aflibercept) in patients with neovascular (wet) age-related macular degeneration (nAMD). Methods This phase III, multicenter, double-blind study was conducted…
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Artikel Jurnal
A Retrospective Review of Glueless, Sutureless Pterygium Excision Using Biovance Triple-Layer Decellularized Amniotic Basement Membrane Tissue
Abstract Introduction A retrospective analysis was performed to determine if a glueless, sutureless surgical technique utilizing a triple-layer dehydrated, decellularized amniotic basement membrane tissue, combined with short exposure to mitomycin‑C (MMC), can reduce recurrence and complications…
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Artikel Jurnal
Reassessment of the Collaborative Normal-Tension Glaucoma Study: Statistical Evidence and Implications for Current Management
Abstract Introduction The Collaborative Normal-Tension Glaucoma Study (CNTGS) is frequently cited as evidence that a 30% reduction in intraocular pressure (IOP) slows progression in normal-tension glaucoma (NTG). This study re-examines the statistical methodology of CNTGS to assess how its…
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Artikel Jurnal
Environmental Drivers of Dry Eye Disease: A Narrative Review of Pollutants, Climate, and Indoor Exposures with Practice Recommendations
Abstract Dry eye disease (DED) is a multifactorial and prevalent condition of the ocular surface that is associated with a wide range of risk factors. In the modern world, environmental conditions and pollution have become increasingly relevant contributors. Recent findings from the Tear Film &…
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Artikel Jurnal
Consensual Ophthalmotonic Reaction in Fellow Eyes in the Early Postoperative Period Following Unilateral Glaucoma Surgery
Abstract Introduction Consensual ophthalmotonic reaction (COR) refers to consensual intraocular pressure (IOP) change in the fellow eye following alteration of IOP in one eye. The study aimed to investigate COR and the magnitude of consensual IOP change after unilateral glaucoma surgery. Methods We…
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Artikel Jurnal
LipiFlow and the Transformation of Therapeutic Meibomian Gland Expression into Routine Clinical Practice
Abstract In 2011, meibomian gland dysfunction (MGD) was officially recognized as a condition that necessitated treatment with the goal of improving ocular symptoms. This was a tipping point in the understanding of MGD and the need for treatment. After 2011, there was an exponential increase in the…
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Artikel Jurnal
Artificial Intelligence-Based Medical Devices for Diabetic Retinopathy Screening in the European Union
Abstract Background Diabetic retinopathy (DR) remains a leading cause of preventable blindness, yet screening programs across Europe face persistent workforce and capacity constraints amid rising diabetes prevalence. Artificial intelligence (AI)-enabled screening platforms have been developed to…
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