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GMS Infectious Diseases
ISSN 2195-8831 · German Medical Science GMS Publishing House · 108 artikel di indeks
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Artikel Jurnal
Next-generation point-of-care diagnostics for urinary tract infections: a systematic review of rapid pathogen detection methods
Background: Urinary tract infections are among the most prevalent bacterial infections worldwide, with Escherichia coli as the leading pathogen. Conventional diagnostic methods, including urine culture and antimicrobial susceptibility testing, require 48–72 hours, often delaying targeted therapy…
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Artikel Jurnal
Effect of targeted screening and decolonisation for methicillin-sensitive Staphylococcus aureus (MSSA) in elective hip and knee arthroplasty
Background: Nasal and pharyngeal colonization with Staphylococcus aureus (S. aureus) is a major risk factor for postoperative wound infections, particularly following orthopedic procedures. Preoperative targeted decolonisation reduces surgical site infections (SSIs) and is recommended by several…
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Artikel Jurnal
Infektionsdiagnostische Handlungskompetenzen von Studierenden der Humanmedizin als essenzielle Grundlage für eine ärztliche Resilienz gegenüber zukünftigen infektionsmedizinischen Herausforderungen
Teaching in the field of “Medical Microbiology, Virology, and Hygiene” focuses on the development of clinical competence in infection medicine, primarily achieved through time- and cost-intensive practical courses, which often compete with other educational offerings. These courses must address the…
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Artikel Jurnal
Proposed guidelines on the evaluation of non-antibiotic versus antibiotic agents indicated for treatment of uncomplicated acute cystitis in adult female patients
Since several current clinical guidelines also recommend non-antibiotic therapy of uncomplicated acute cystitis (uAC) in women, research guidelines are needed on conducting clinical trials to demonstrate their efficacy compared to e.g. standard antibiotic therapy. As the mechanism of action of…
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Artikel Jurnal
Identification of a new Salmonella serovar – Salmonella Weitmar (8:z41:1,5)
We report the first human case of a novel Salmonella enterica serovar Weitmar (8:z41:1,5), isolated from a 41-year-old outpatient with acute diarrhea and fever in Bochum, Germany. Identification involved culture, multiplex PCR, MALDI-TOF MS, biochemical testing, and reference lab serotyping. The…
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Artikel Jurnal
Analysis of multidrug-resistant Gram-negative pathogens (MRGN) in different areas of the healthcare system and their significance in the outpatient sector
Given the global threat of increasing antibiotic resistance, risk factor detection of multi-resistant pathogens is particularly important. This is complicated by different definitions, using the international extended spectrum beta-lactamases (ESBL) definition and the German definition of…
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Artikel Jurnal
Does antibiotic prophylaxis for dental treatment prevent periprosthetic infections?
Background: The German Society for Arthroplasty (AE) recommends a single dose of 2,000 mg amoxicillin as an antibiotic prophylaxis to prevent periprosthetic joint infections (PJI) in patients with total hip or knee arthroplasty (THA, TKA) who undergo invasive dental procedures (DP). We searched for…
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Artikel Jurnal
Identification of a new Salmonella serovar – Salmonella Scharmann (8:z41:1,5)
We report the first human case of a novel Salmonella enterica serovar Scharmann (8:z41:1,5), isolated from a 41-year-old outpatient with acute diarrhea and fever in Bochum, Germany. Identification involved culture, multiplex PCR, MALDI-TOF MS, biochemical testing, and reference lab serotyping. The…
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Artikel Jurnal
(Fluoro)quinolone prescriptions for upper respiratory tract infections in the German outpatient sector: a health insurance claims analysis
Background: Acute upper respiratory tract infections (URTIs) are frequent causes of medical treatment by general practitioners (GPs). In general, these are viral and self-limiting illnesses, but antibiotics are prescribed. In Germany, fluoroquinolones are not authorised for the indications…
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Artikel Jurnal
Impact of an antimicrobial stewardship program on colistin resistance in a tertiary care hospital in Pakistan: a quasi-experimental study
Background: Colistin is a last-resort antibiotic used against infections caused by multidrug-resistant gram-negative organisms, particularly carbapenem-resistant strains. Rising resistance to colistin is a significant global concern. To address this, an Antimicrobial Stewardship (AMS) Program was…
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Artikel Jurnal
Antibiotic susceptibility pattern of Campylobacter sp. isolated from human stool samples including comparison of ellipsoid test and broth microdilution for meropenem
Foodborne campylobacteriosis is the most common cause of bacterial gastroenteritis in Germany. Due to increasing antibiotic resistance in Campylobacter, data of isolates of human origin are published by the European Center for Disease Control and Prevention (ECDC)/European Food Safety Authority…
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Artikel Jurnal
COVID-19 as cause of death: a bridge coding study
Background: The number of COVID-19 deaths is an important measure for the impact of the pandemic. However, estimates differ and fuel the debate on COVID-19 as legitimate cause of death. Objective: To study the role of COVID-19 as cause of death. Methods: Double (bridge) coding of all death…
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Artikel Jurnal
Cartridge-based nucleic amplification (CBNAAT)/GeneXpert test as a diagnostic modality for the detection of genital tuberculosis in women with infertility
Background: Genital tuberculosis (GTB) is a significant etiological factor of infertility in developing countries such as India; however, it is frequently undiagnosed due to its asymptomatic nature and a lack of standardised protocols. This study aimed to compare the diagnostic efficacy of…
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Artikel Jurnal
Challenges in laboratory diagnosis and antibiotic treatment options for a newly described Pseudomonas aeruginosa class A beta-lactamase type GES-62 strain
Antibiotic resistance is a major challenge in modern healthcare, as it severely limits the choice of treatment options. In particular, carbapenemase mediated carbapenem resistance in Pseudomonas aeruginosa poses an emerging health risk worldwide. Here, we discovered a hitherto unknown variant of…
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Artikel Jurnal
A complex case of bacterial pericarditis caused by a new pathogenic agent
is a gram-positive facultative anaerobic agent. It is a human skin colonizer that can be responsible for opportunistic infections in immunocompromised patients. To date, the infections caused by this agent are related to bone, joint, eye, peritoneal dialysis catheters, abscesses or infected…
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Artikel Jurnal
Fusarium spp.: infections and intoxications
The genus , member of the family, comprises over 500 spp. with an ever-evolving taxonomy. These fungi, some highly pathogenic, primarily affect various plants, including major crops like maize, rice, cereals, and potatoes, leading to significant agricultural losses and contributing to human…