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Bioresources and Bioprocessing
Scopus
ISSN 2197-4365 · SpringerOpen · 980 artikel di indeks
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Artikel Jurnal
Eco-friendly alternatives to seed chemical coating: agro-industrial byproducts as seed treatments with long-term effects on growth and reproduction
Abstract Synthetic chemical seed treatments, while effective, often raise significant environmental and health concerns. These concerns stem from the use of hazardous chemicals such as fungicides and insecticides that, besides posing risks to workers, have broader environmental impacts. These…
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Artikel Jurnal
Anti-angiogenesis effect of Baiying Juhua Decoction on the non-small cell lung cancer: integrating pharmacology, multi-machine learning and experimental investigation
Abstract Baiying Juhua Decoction (BYJHD) is a well-established traditional Chinese herbal formula primarily composed of Solanum lyratum and chrysanthemum, which necessitates a thorough investigation to clarify its mechanisms in combating non-small cell lung cancer (NSCLC). This study employed a…
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Artikel Jurnal
Ulvan and Ulva oligosaccharides from Ulva sp. attenuate osteoarthritis in a high-fat diet and ligamentous meniscal injury-induced rat model
Abstract Osteoarthritis (OA) is a chronic joint disease. It is marked by the progressive deterioration of subchondral bone, articular cartilage, and synovium, with obesity acting as a significant risk factor by promoting inflammation and cartilage degradation. Ulvan and Ulva oligosaccharides…
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Artikel Jurnal
Integration of pathway balance and protein fusion enables de novo biosynthesis of (+)-bicyclogermacrene in Escherichia coli
Abstract (+)-Bicyclogermacrene and its derivatives, with promising antimicrobial, anticancer, and insecticidal properties, hold significant potential for applications in pharmaceuticals, agriculture, and industry. However, traditional extraction methods from plant essential oils are unsustainable…
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Artikel Jurnal
Enhanced synthesis of 1, 3-medium chain-2-long chain triacylglycerols by engineered Saccharomyces cerevisiae
Abstract Enzymatic synthesis is currently the primary method for preparing 1,3-medium chain- 2-long-chain triacylglycerols (MLM-TAGs), which serve as both a dietary component and clinical nutrient for specific populations. The application of MLM-TAGs is obviously constrained by the high cost of…
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Artikel Jurnal
Fabrication of a 3D nano-bienzyme cascade reactor based on a Dps protein scaffold for chiral amine synthesis
Abstract Based on the self-assembling properties of the SpyCatcher/SpyTag system and the structural advantages of Dps protein, this study successfully constructed a three-dimensional nano-enzyme cascade reactor (3DNECR) through the covalent self-assembly of SpyTag-ADH and SpyCatcher-Dps-ATA117…
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Artikel Jurnal
Thermostability engineering of microbial transglutaminase using artificial intelligence and investigation of its underlying mechanisms
Abstract The application of artificial intelligence in enzyme molecular evolution has emerged as a research hotspot. However, applying machine learning to enzyme molecular modification still presents many challenges. In particular, accelerating the integration of machine learning and rational…
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Artikel Jurnal
Acid adaptation of Lactobacillus helveticus during continuous cultures to improve undissociated lactic acid production
Abstract This study aims at improving the undissociated lactic acid production by Lactobacillus helveticus using a whey-based fermentation. It first describes the effect of pH on the ability of this bacterium to produce lactic acid, by considering final lactic acid concentration, production rate…
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Artikel Jurnal
Multi-AOP: a lightweight multi-view deep learning framework for antioxidant peptide discovery
Abstract Antioxidant peptides (AOPs), with their strong free radical scavenging ability and health benefits, have emerged as promising candidates for disease prevention and food preservation. However, traditional experimental approaches to AOP discovery remain hindered by inefficiencies and…
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Artikel Jurnal
Box-Behnken optimized copper oxide nanoparticles from Thymus vulgaris potentiate efficacy against multidrug-resistant bacterial pathogens and exhibit anticancer activity
Abstract The dual crises of antimicrobial resistance and cancer demand innovative therapeutic platforms that overcome conventional treatment limitations. This study uniquely combines systematic Box-Behnken optimization of green-synthesized copper oxide nanoparticles from Thymus vulgaris with…
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Artikel Jurnal
Coupled rhizosphere application of cyanobacteria-bamboo acid hydrolysis extract and cyanobacterial biochar enhances soil health and crop quality
Abstract Driven by waste resource utilization and carbon neutrality imperatives, this study synthesized cyanobacterial growth elicitor (CGE) and cyanobacterial-bamboo growth elicitor (CBGE) via acid-hydrothermal hydrolysis. The coupling potential of cyanobacterial biochar (CB) for improving…
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Artikel Jurnal
Tailored biochar from oil palm trunk via controlled carbonization for efficient dye adsorption
Abstract Oil palm trunks (OPT) represent an underutilized agricultural byproduct that poses significant environmental challenges. The effectiveness of OPT as feedstock for biochar production will be depends on carbonization conditions, yet the relationship between process parameters and biochar…
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Artikel Jurnal
Propionate-engineered probiotics reduce radiation-induced intestinal damage
Abstract Radiation enteritis is a common complication in patients undergoing abdominal radiotherapy. Current management strategies face significant limitations: clinical agents like amifostine are hindered by systemic side effects and demanding administration; direct supplementation with…
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Artikel Jurnal
Continuous autotrophic production of alcohols with Clostridium autoethanogenum LAbrini in a submerged membrane bioreactor
Abstract Due to the generally low growth rates of acetogens, conventional batch and continuously operated syngas fermentation processes in suspension cultures, e.g., stirred tank bioreactors, typically result in low cell concentrations and, thus, limited volumetric productivities (space-time…
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Artikel Jurnal
Enhanced production of phomapyrrolidone a through culture-condition optimization and morphological regulation in Didymella sp. FATR0054
Abstract Phomapyrrolidone A (Ppd A) is a hirsutellone-type macrocyclic alkaloid derived from marine fungi, exhibiting significant activity against triple-negative breast cancer (TNBC). However, its low fermentation yield has limited further drug development. This study established a systematic…
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Artikel Jurnal
Disruption or partitioning? Deep eutectic solvent biphasic systems for integrated seaweed biorefineries
Abstract In this study, a DES-based biphasic system (FABU) was evaluated for the multiproduct extraction of compounds from Saccharina latissima. The system combined a hydrophobic fatty-acid phase (dodecanoic acid–octanoic acid, FA) for fucoxanthin extraction with a hydrophilic betaine-urea-phase…
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Artikel Jurnal
Optimization of pulsed electric field pretreatment followed by cellulase hydrolysis for enhanced protein recovery and antioxidant activity from brown seaweed (Undaria pinnatifida)
Abstract Undaria pinnatifida is a promising brown seaweed due to its relatively high protein content and functional bioactive compounds. However, efficient recovery of these components is limited by its rigid, polysaccharide-rich cell wall structure. In this study, pulsed electric field (PEF)…
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Artikel Jurnal
Integrated hydrothermal and microbial valorization of almond shells into xylooligosaccharides and cellobionic acid
Abstract Almond shells are abundant lignocellulosic by-products with great potential for sustainable valorization. This study developed an integrated biorefinery process to produce xylooligosaccharides (XOS) and cellobionic acid (CBA) through hydrothermal pretreatment and fungal simultaneous…
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Artikel Jurnal
Optimized microwave pretreatment and ultrasound-assisted deep eutectic solvent extraction for efficient valorization of Citrus paradisi peel bioactives
Abstract This study presents a sustainable approach for recovering bioactive compounds from grapefruit (Citrus paradisi) peel using a glycerol–glucose-based deep eutectic solvent as a green extraction medium. Spectroscopic characterization confirmed the formation of stable hydrogen-bonded eutectic…
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Artikel Jurnal
Mechanistic investigation of UV-irradiated neem oil against microbial biofilms and A431 skin cancer cells via Bax/Bcl2/caspase-3 modulation
Abstract Neem oil (Azadirachta indica) possesses antimicrobial and anticancer properties, but its clinical translation is limited by variable chemical profile and suboptimal bioavailability. Ultraviolet (UV) irradiation is a green, non-thermal physical modification technique that can alter…