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Clinical Phytoscience
ISSN 2199-1197 · SpringerOpen · 389 artikel di indeks
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Artikel Jurnal
Exploring the phytochemistry, extraction techniques, and therapeutic potentials of Dryopteris species: a scoping review (2010–2025)
Abstract Dryopteris, often referred to as wood or shield ferns, constitutes a globally ubiquitous genus within the Dryopteridaceae family, thriving in a wide array of habitats that encompass temperate woodlands to tropical montane ecosystems. This investigation examines the phytochemical…
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Artikel Jurnal
The role of plant-derived compounds in the management and prevention of urolithiasis: a review of evidence and mechanisms
Abstract Urolithiasis, the condition of forming stones in the urinary system, is a common health problem worldwide and tends to recur. Pathophysiology includes stages such as supersaturation, nucleation, growth, aggregation, and crystal-cell interactions. Most conventional treatments have…
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Artikel Jurnal
The therapeutic role of medicinal plants in the management of diabetes
Abstract Background Millions of people worldwide suffer from diabetes mellitus, a chronic metabolic disease marked by hyperglycemia that calls for a variety of treatment approaches. Despite the availability of traditional therapies, many people, especially in developing nations, turn to medicinal…
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Artikel Jurnal
A comprehensive review on Alangium Salvifolium: a phyto-pharmacological update
Abstract For centuries, herbal drugs have been used in conventional medicine and are now gaining recognition for their therapeutic potential. Alangium salvifolium (Linn. F) Wang (A. salvifolium), widely known as Ankol, is an esteemed herbal plant in traditional medicine, historically used for…
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Artikel Jurnal
The effect of phytoneering extracts BNO 1016 and BNO 1030 on the adhesion of typical respiratory pathogens: an experimental study
Abstract Background Rhinosinusitis and tonsillitis are associated with the formation of bacterial biofilms, which complicates treatment and contributes to frequent relapses. Microbial adhesion to host cells is a key initial step in colonization and biofilm development. Phytoneering extracts BNO1016…
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Artikel Jurnal
Plant-based nephroprotective agents: a review of strategies to combat drug-induced kidney damage
Abstract Kidney diseases, exacerbated by drug-induced nephrotoxicity, remain a significant global health burden as it is linked to diabetes and hypertension, presenting a global health challenge. Conventional treatments often have nephrotoxic side effects, complicating disease management…
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Artikel Jurnal
Enhanced antimicrobial and antibiofilm effects of Baccaurea ramiflora Lour. fruit extract combined with FMSP-nanoparticles against multidrug-resistant bacteria: an in vitro and in silico analysis
Abstract Background The increasing prevalence of antimicrobial resistance (AMR) and biofilm-associated infections poses significant challenges to public health. This study investigated the antibacterial and antibiofilm potential of ethanol extracts of Baccaurea ramiflora Lour. (B. ramiflora) peel…
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Artikel Jurnal
Clinical evaluation of a standardized botanical formulation in type 2 diabetes using a unified incretin therapeutic index
Abstract Background Botanical formulations enriched with polyphenols, bitter phytoconstituents, dietary fibers, and alkaloids have traditionally been used for the management of metabolic disorders. However, standardized clinical evaluation frameworks capable of integrating multisystem therapeutic…
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Artikel Jurnal
From tradition to therapy: novel clove formulations in periodontal therapy
Abstract Background Microbial infection and inflammatory reactions play important roles in the inflammation and degeneration of tooth-supporting structures that characterize periodontal diseases. Clove (Syzygium aromaticum) is a promising option for periodontal therapy because it contains bioactive…
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Artikel Jurnal
Hypoglycemic effect of Hydrocotyle bonariensis Comm. Ex Lam. leaf extract in an experimental type 2 diabetes rat model
Abstract Background Hydrocotyle bonarensis Comm. Ex Lam. (Araliaceae) leaf water infusion is traditionally used in the treatment of diabetes mellitus (DM) in Côte d’Ivoire and other parts of Africa. However, scientific studies validating these claims are limited. Objective The study was designed to…
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Artikel Jurnal
A comprehensive review on Ziziphus spina-christi gum–alginate composite beads: from physicochemical properties to advanced sustained-release applications
Abstract Background The gradual release of a drug over a longer period of time is an important area of modern pharmaceutical research which includes sustained release drug delivery systems. This controlled release maintains therapeutic concentrations of the drug in plasma and reduces the dosage…
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Artikel Jurnal
Nanocarrier-enabled restoration of miR-34a by Ailanthus excelsa Roxb. phytochemicals directly target NOTCH1 signaling to suppress cancer stemness in triple-negative breast cancer
Abstract Background Triple-negative breast cancer (TNBC) is a highly aggressive breast cancer subtype associated with poor prognosis, metastasis, and limited targeted therapies. This study developed a folate-functionalized chitosan nanoparticle system targeting the miR-34a/NOTCH1 signaling axis and…
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Artikel Jurnal
Antidiabetic and antidyslipidemic effects of Ziziphus nummularia leaf and fruit extracts alone and in combination with vildagliptin in alloxan-induced diabetic rats
Abstract Background Diabetes mellitus is a chronic metabolic disorder characterized by persistent hyperglycaemia and dyslipidaemia, leading to severe microvascular and macrovascular complications. Although vildagliptin is an effective dipeptidyl peptidase-4 (DPP-4) inhibitor, combination strategies…
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Artikel Jurnal
Combining swim exercise and Ocimum gratissimum leaf extract: a dual approach to mitigate cardiometabolic derangement in obese male Wistar rats
Abstract The mitigative potential of Ocimum gratissimum aqueous leaf extract (OG) in metabolic diseases is well documented. The impact of exercise on its cardiometabolic effect in obese male Wistar rats is however not known, hence the current study. Twenty-five, 4 weeks old, male Wistar rats were…
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Artikel Jurnal
Molecular and immunological insights into honey as a complementary approach in hepatocellular carcinoma: a systematic review
Abstract Hepatocellular carcinoma (HCC) is a rising worldwide health problem characterized by high mortality. The presence of early asymptomatic phases, the delay in diagnosis, and limited options for curative surgical interventions all enhanced its severity. Various contributing factors, including…
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Artikel Jurnal
Translational evidence for the antihypertensive potential of Passiflora edulis: a systematic review of preclinical and clinical studies
Abstract Introduction Passiflora edulis (PE) (passion fruit) is traditionally valued for its cardiovascular and calming properties, but its antihypertensive and blood pressure (BP)-lowering potential has not been systematically evaluated. Emerging evidence from preclinical and clinical studies…
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Artikel Jurnal
Association of rosemary leaves and day lily flowers: evaluation of its antidepressant-like effects in mice
Abstract Background R. officinalis has been used as a nervous tonic and cognitive stimulant. H. fulva has been employed to relieve anxiety, insomnia, and depressive symptoms. Here, we evaluated the effects of an herbal formulation containing rosemary leaves and day lily flowers in a…
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Artikel Jurnal
Bioactive metabolites of Launaea taraxacifolia (Willd.) Amin ex C. Jeffrey and their mechanistic roles in cancer suppression
Abstract Background Launaea taraxacifolia (Willd.) Amin ex C. Jeffrey is a traditionally recognized medicinal plant with reported anticancer potential; however, it remains largely underutilized and is often regarded as a wild or neglected species. This review presents a comprehensive and up-to-date…
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Artikel Jurnal
Herbal interventions for the management of type 2 diabetes mellitus: a narrative review of clinical evidence, mechanisms, and translational challenges
Abstract Background Type 2 diabetes mellitus (T2DM) is a major and growing global health burden, and many people use herbal products alongside conventional therapy. Although numerous clinical trials and evidence syntheses have evaluated herbal interventions, the certainty, reproducibility, safety…
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Artikel Jurnal
Influence of cooking and fractionation of Momordica balsamina L. (Cucurbitaceae) leaves on hypolipidemic and antioxidant properties in rats fed a high-fat diet
Abstract Background Momordica balsamina leaves are widely consumed for their nutritional and therapeutic properties. This study evaluated the effect of cooking and granulometric fractionation of M. balsamina leaf powders on their extractable bioactive compound content, antioxidant activities, and…