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Journal of Global Antimicrobial Resistance
Scopus
ISSN 2213-7165 · Elsevier · 2.202 artikel di indeks
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Artikel Jurnal
Antibacterial resistance in urinary samples from long-term care-facility and community-dwelling older people in Gauteng, South Africa
Objective: Older populations (≥ 60 years) are frequent users of health care services, often vulnerable to infections and antimicrobial resistance (AMR). Urinary tract infection is often diagnosed in this cohort based on non-specific or atypical symptoms, yet empirical therapy seldom considers the…
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Artikel Jurnal
Antimicrobial susceptibility analysis of diarrhoeagenic Escherichia coli isolated from outpatients in Beijing, from 2021 to 2024
Objectives: This study aimed to investigate the prevalence of diarrhoeagenic Escherichia coli (DEC) among outpatients in Beijing, and to analyse the antimicrobial susceptibility profiles and antimicrobial resistance gene characteristics of the isolated strains. Methods: From 2021 to 2024, DEC…
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Artikel Jurnal
Genomic analysis of a penicillin-susceptible, methicillin-resistant Staphylococcus aureus (ST9332) harboring triple mecA substitutions
Research Background: mecA-positive MRSA is generally assumed to be broadly non-susceptible to β-lactams. Reports of penicillin-susceptible MRSA (PS-MRSA) challenge this view. We describe CDSYY2023, a cefoxitin-resistant yet penicillin-susceptible MRSA carrying three mecA substitutions (S225R…
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Artikel Jurnal
Antimicrobial resistance in the Bacteroides fragilis group: National multicenter survey and Bayesian modelling study, France, 2022–2023
Objectives: Epidemiological studies on Bacteroides fragilis group (BFG) species and their antimicrobial resistance (AMR) profiles remain scarce worldwide and are lacking in France. The aim of this study was to provide comprehensive national data on the distribution of BFG species, isolation sites…
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Artikel Jurnal
Barriers and facilitators to the implementation of antimicrobial stewardship in veterinary education: A scoping review
Objective: To identify the barriers and facilitators to implement antimicrobial stewardship (AMS) in veterinary education globally. Methods: Following PRISMA-Scoping review guidelines and Arksey and O’Malley’s framework, this review analysed studies published between 2015 and 2025 from databases…
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Artikel Jurnal
Intervention studies and antimicrobial resistance in Italy: An overview of the latest evidence
Objective: Antimicrobial resistance (AMR) poses a significant and growing threat to public health globally, with Italy facing some of the highest resistance rates in Europe. This manuscript reviewed recent Italian intervention studies aimed at mitigating AMR across bacterial, fungal, and viral…
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Artikel Jurnal
In vitro activity of vancomycin and other commonly used Antibiotics against clinical isolates of Enterococcus faecalis and Enterococcus faecium: Data from the antimicrobial testing leadership and surveillance (ATLAS) program from 2019 to 2023
Objectives: Enterococci are significant hospital pathogens, posing a serious global public health threat. This study aimed to analyze the in vitro susceptibility of enterococcal isolates to eight commonly used antibiotics and to explore cross-resistance patterns in vancomycin-resistant enterococci…
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Artikel Jurnal
A combination of Mycobacterium tuberculosis-derived sRNA and endogenous miRNA in circulation as novel auxiliary diagnostic markers for patients with multidrug-resistant tuberculosis
Objective: Circulating non-coding small RNAs (sRNAs) have recently emerged as promising biomarkers for Mycobacterium tuberculosis (Mtb). However, little is known about the expression patterns and combined diagnostic potential of M. tuberculosis-derived sRNA (TB-sRNA) and endogenous miRNA in the…
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Artikel Jurnal
Characterization of tmexCD2-toprJ2-carrying carbapenem-resistant Raoultella ornithinolytica from hospital sewage in Zhejiang Province of China, 2022–2023
Objective: Hospital wastewater serves as a critical source of antimicrobial resistance genes (ARGs), particularly those associated with opportunistic pathogens like Raoultella ornithinolytica. This study aimed to characterize carbapenem-resistant R. ornithinolytica (CR-ROR) isolates carrying the…
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Artikel Jurnal
Evaluating the performance of the InnowaveDx MTB/RIF/INH for simultaneous detection of Mycobacterium tuberculosis and resistance to rifampicin and isoniazid
Objective: To evaluate the diagnostic performance of the InnowaveDx MTB/RIF/INH assay for the simultaneous detection of Mycobacterium tuberculosis and resistance to rifampicin and isoniazid. Methods: We evaluated the performance of the InnowaveDx MTB/RIF/INH (InnowaveDx) assay in diagnosing…
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Artikel Jurnal
Deconstructing antimicrobial resistance national action plans: A gender-perspective driven mixed-methods analysis
Introduction: Antimicrobial resistance (AMR) is a major global health threat addressed through National Action Plans (NAPs) aligned with the WHO Global Action Plan. Despite evidence that women are disproportionately affected – receiving 27% more antibiotic prescriptions than men – gender…
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Artikel Jurnal
Multicentric evaluation of the MTS™ Synergy Application System for reliable antibiotic synergy testing in clinical laboratories
Objectives: The rise of antimicrobial resistance poses a major challenge for both clinicians and clinical microbiologists. There is an increasing need for user-friendly and reliable methods to assess the activity of antibiotics against multidrug-resistant (MDR) strains. Although synergy testing…
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Artikel Jurnal
Dissemination of NDM-1-producing Pseudomonas aeruginosa ST308 and ST274 high-risk clones in Argentina
Objective: This study describes the phenotypic, molecular, and genomic characterisation of emerging blaNDM-1-producing Pseudomonas aeruginosa in Argentina, mainly driven by ST308 and ST274 clones. Methods: Nineteen clinical isolates submitted to the National and Regional Reference Laboratory on…
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Artikel Jurnal
Clinical outcome comparison between adjunctive clindamycin vs. linezolid for invasive group A streptococcal infection
Purpose: Although the non-inferiority of adjunctive linezolid (LZD) was indicated for the treatment of invasive group A streptococcal (iGAS) infection, compared with adjunctive clindamycin (CLDM), additional evaluation of comparative effectiveness by subpopulation may further strengthen the…
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Artikel Jurnal
Impact of DNA methyltransferases on bacterial fitness and genome stability in Escherichia coli
Objective: DNA methylation, catalysed by DNA methyltransferases (MTases), plays a crucial role in bacterial physiology. In this study, we investigated the effects of the DNA MTases, DNA adenine methyltransferase (Dam) and DNA cytosine methyltransferase (Dcm), on bacterial fitness and mutation rates…
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Artikel Jurnal
Impact of antimicrobial prophylaxis in colorectal cancer surgery on the gut and oral microbiome and resistome: A prospective observational cohort study
Background: The use of antibiotics may facilitate the colonisation of antimicrobial-resistant organisms and genes within the host microbiome. However, studies on the effects of antibiotics on microbiomes and resistomes in clinical settings are limited. Aim: The aim of this study was to determine…
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Artikel Jurnal
Genomic insights into a multidrug-resistant uropathogenic Escherichia coli ST131-H30 strain associated with a fatal healthcare-associated infection
Objective: Uropathogenic Escherichia coli (UPEC) poses a significant public health challenge due to increasing antimicrobial resistance (AMR) and severe infections. This study aimed to investigate the genetic heterogeneity and AMR mechanisms of a clinical UPEC strain associated with a fatal…
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