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European Thyroid Journal
Scopus
ISSN 2235-0802 · Bioscientifica · 391 artikel di indeks
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Artikel Jurnal
The influence of age-independent somatic driver alterations on clinical outcomes in paediatric and young adult thyroid cancer
Background: Paediatric and young adult differentiated thyroid carcinoma (DTC) often presents at an advanced stage but carries an excellent prognosis. While age-related genomic differences from adult DTC are recognized, it remains unclear whether outcomes are driven by age or tumour biology…
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Artikel Jurnal
Network toxicology and Mendelian randomization reveal pathogenic factors of monoethyl phthalate-induced thyroid cancer
Monoethyl phthalate, a major metabolite of phthalate esters, is commonly found in the environment and has been linked to an increased risk of thyroid cancer. This study uses network toxicology to predict molecular initiators involved in monoethyl phthalate-induced thyroid cancer and to explore…
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Artikel Jurnal
lncRNAs: a new generation of targets and biomarkers in thyroid cancer
Long non-coding RNAs (lncRNAs) are untranslated RNA molecules that regulate gene expression through diverse mechanisms, acting as scaffolds, guides, decoys, or signals. In thyroid cancer, the most prevalent endocrine malignancy, lncRNAs are increasingly recognized as key contributors to tumor…
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Artikel Jurnal
Predictors of retreatment after radiofrequency ablation of benign thyroid nodules: role of pre-treatment growth rate and viable volume
Background: Radiofrequency ablation (RFA) has emerged as a minimally invasive and effective alternative to surgery for benign thyroid nodules, providing a significant volume reduction and symptom relief. However, approximately one in five patients experiences regrowth requiring retreatment. This…
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Artikel Jurnal
Newborn screening for congenital hypothyroidism in France: a study of current professional practices
Objective: Congenital hypothyroidism is a leading cause of preventable intellectual disability. Neonatal screening enables early detection and treatment, ideally before symptoms appear. In France, screening has been part of national public health policy since 1978, relying on standardized protocols…
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Artikel Jurnal
Brain fatigue in Graves’ disease: symptoms and presentation of a possible mechanism at the cellular level
Fatigue in patients with Graves’ disease (GD) is characterized by a profound lack of mental energy that affects daily functioning, including work. This symptom is particularly prominent in the early stages of the disease, affecting more than 50% of patients, but in some cases, it persists even…
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Artikel Jurnal
Artificial intelligence-assisted risk stratification of thyroid nodules with atypia of undetermined significance
Objective: Given the limitations of conventional approaches in managing indeterminate thyroid nodules, there remains an unmet need for non-invasive assistant tools to improve risk stratification. This study aimed to evaluate the clinical applicability of an artificial intelligence (AI) model for…
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Artikel Jurnal
Clinical presentation and outcomes of medullary thyroid cancer in two European countries: impact of diagnostic strategies
Objective: To evaluate differences in clinical presentation, diagnostic and therapeutic modalities, and outcomes in two cohorts of patients with sporadic medullary thyroid carcinoma (MTC) from reference centres in Italy and the Netherlands. The two centres have different diagnostic approaches…
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Artikel Jurnal
The caprices of a trace element: selenium’s considerable effects on Hashimoto’s thyroiditis, though few on Graves’ disease
A simplified figure displaying the main events leading to Hashimoto’s thyroiditis and Grave’s disease via Th1 and Th2 activation, and the potential sites of selenium (Se) action. (A) Activated by the dendritic cell, naïve helper T cells (CD4+ T cells) can mainly differentiate into two subsets, Th1…
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Artikel Jurnal
What has changed in thyroid eye disease in the last five years (2020–2025)
Background: Significant progress has been made in the management of thyroid eye disease (TED), based on the elucidation of important pathogenic mechanisms. This has led to novel therapeutics validated in randomized clinical trials. Autoreactive antigens that elicit specific orbital immune reactions…
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Artikel Jurnal
Hypercalcitoninemia in chronic kidney disease: an old issue, a new perspective?
Objective: Chronic kidney disease (CKD) has been reported in association with hypercalcitoninemia, but the calcitonin (Ct) values to expect in CKD patients are unknown. This study aimed to evaluate Ct levels in CKD patients using an accurate chemiluminescent immunoassay. Methods: Two population…
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Artikel Jurnal
Preconception body mass index and maternal thyroid function: a longitudinal observational study
Objective: The objective of this study was to examine the association between preconception body mass index (p-BMI) and maternal thyroid function longitudinally evaluated over pregnancy and to explore whether early-pregnancy thyroid parameters are associated with adverse obstetric outcomes…
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Management of thyroid emergencies: joint consensus statement on management of thyroid storm
Thyroid storm is a rare but life-threatening endocrine emergency characterised by extreme thyrotoxicosis and multi-organ dysfunction. Prompt recognition and rapid, coordinated management are essential to reduce its high mortality. This consensus statement, developed by experts in endocrinology and…
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Artikel Jurnal
2026 ETA guideline on interference in immunoassay measurements used in assessment of thyroid function
Although measurement of thyroid hormones (THs), TSH and thyroid autoantibodies, is usually straightforward, erroneous results are occasionally generated, raising the possibility of incorrect or delayed diagnoses, unwarranted investigations, and provision of inappropriate treatments. Assay…
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Artikel Jurnal
TNFα drives disease-specific chemokine networks and orbital tissue remodeling in a preclinical model of thyroid eye disease
Background: Thyroid eye disease (TED) is characterized by orbital inflammation, fibroblast activation, and pathological tissue remodeling. While autoimmunity to the thyrotropin receptor (TSHR) initiates disease, the contribution of proinflammatory cytokines, such as tumor necrosis factor (TNFα), to…
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Artikel Jurnal
Management of endocrine emergencies: joint consensus statement for management of myxoedema coma
Myxoedema coma is a rare, life-threatening endocrine emergency resulting from severe hypothyroidism, most commonly affecting older adults. It is characterised by altered mental status, hypothermia, and multiorgan dysfunction, with a high mortality rate if not promptly recognised and treated. This…
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Artikel Jurnal
Association between thyroid hormone and pre-sarcopenic obesity in euthyroid population: a prospective cohort study
Objective: We aimed to explore the association between thyroid indicators and pre-sarcopenic obesity, pre-sarcopenia, and visceral obesity in a community-based euthyroid cohort. Methods: A total of 1,280 euthyroid residents (42.3% men) aged over 40 years were recruited in 2013–2014 and re-examined…