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The World Journal of Men's Health
Scopus
ISSN 2287-4208 · Korean Society for Sexual Medicine and Andrology · 629 articles in the index
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Journal Article
The Effects of Varicocele Repair on Testicular Sperm Retrieval, Sperm Recovery in the Ejaculate and Clinical Pregnancy Rates in Non-Obstructive Azoospermic Men with Clinical Varicocele: A Systematic Review and Meta-Analysis
Purpose: The role of varicocele repair (VR) in infertile men with non-obstructive azoospermia (NOA) and varicocele is controversial in the current guidelines, despite available studies. This study aims to assess the impact of VR on testicular sperm retrieval, sperm recovery from the ejaculate, and…
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Journal Article
Evidence for the Additional Health Benefits Associated with Phosphodiesterase 5 Inhibitors when Used for Treating Erectile Dysfunction, with a Focus on Prostate Cancer Patients and Other Associated Conditions
Erectile dysfunction (ED) affects the majority of prostate cancer (PCa) patients. Although phosphodiesterase 5 inhibitors (PDE5i) are the first-line treatment for ED and are strongly supported by evidence as safe and effective, they remain underutilised in PCa patients. Furthermore, there is a…
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Journal Article
Relationship between Prostate Cancer and Benign Hyperplasia: Role of Inflammation-Induced Oxidative Stress, Vitamin C, and Epigenetics
Benign prostatic hyperplasia and prostate cancer (PC) frequently affect aging men, both involving irregular cell growth in the prostate. Inflammation is a major contributor to these conditions, whereas DNA methylation and hydroxymethylation are specifically involved in PC development. In this…
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Journal Article
The Impact of Cadmium Telluride Quantum Dots on Male Reproductive Health: A Systematic Review of Toxicological Effects and Mechanisms
Cadmium telluride (CdTe) quantum dots (QDs) are widely utilized in biomedical applications because of their unique optical properties. However, concerns regarding their potential reproductive toxicity have emerged, necessitating comprehensive toxicological evaluations. Evidence suggests that…
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Journal Article
N6-Methyladenosine RNA Methylation: A Key Regulator in Male Reproductive Disorders and Urological Cancers
In the field of male health, disorders of the reproductive and urological systems present significant challenges. The global increase in male infertility, primarily attributed to environmental and lifestyle factors, along with the high incidence of urological cancers, not only places a significant…
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Journal Article
Prostate Cancer at the Microbial Crossroads: Illuminating a New Frontier in Precision Medicine
The human body harbors a complex, dynamic community of trillions of microbes, collectively termed the microbiota, which profoundly affects homeostasis and disease processes, including cancer. Prostate cancer remains a major cause of morbidity and mortality among men worldwide; however, critical…
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Journal Article
Seminal Plasma Exosomes in Male Infertility: Roles, Mechanisms, and Applications—A Double-Edged Sword
Exosomes, which are membrane-bound vesicles with diameters of 30 to 150 nanometers, are secreted by nearly all cell types and serve as key mediators of intercellular communication. In the male reproductive system, exosomes originating from reproductive glands, including the testes, epididymis, and…
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Journal Article
The Global State of Contemporary Andrology Practice: A Comprehensive Analysis of Clinical Practice, Training Pathways, and Emerging Challenges
Purpose: This study evaluates the current state of andrology practice worldwide, identifies challenges faced by clinicians, and explores training, certification, and research opportunities. It also seeks to redefine the qualifications necessary to be recognized as an andrologist and to propose…
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Journal Article
A Novel Glycyrrhiza korshinskyi Cultivar ‘Wongam’ Alleviates Benign Prostatic Hyperplasia via G1/S Checkpoint Arrest and Apoptosis: Insights from Network Pharmacology and Experimental Validation
Purpose: In traditional Chinese medicine, benign prostatic hyperplasia (BPH) is attributed to qi deficiency caused by blood stasis, and Glycyrrhiza species (licorice) have long been used to enhance qi, relieve congestion, and promote blood circulation. Wongam (WG), a newly developed licorice…
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Journal Article
Brain Activation Patterns during Sexual Arousal: A Comparative Time-Course Functional Magnetic Resonance Imaging Study in Postoperative Female-to-Male Transgender Individuals, Cisgender Men, and Premenopausal Women
Purpose: This study used functional magnetic resonance imaging with time-course analysis to compare the temporal dynamics of brain activation patterns associated with visual sexual arousal among postoperative female-to-male (FtM) transgender individuals, men, and women. Materials and Methods: A…
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Journal Article
Age Disparity in Couples Seeking First Medical Help for Infertility Has Changed Over the Last Twenty Years: A Socio-Demographic Analysis
Purpose: Epidemiological studies have suggested that men are usually coupled with younger women. Parental age at first child have steadily increased over last decades. Accordingly, the age gap within partners has changed in the real-life setting over the same time frame. To analyze differences in…
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Journal Article
EGFL7 Inhibits the Immune Response in Metastatic Castration-Resistant Prostate Cancer by Deactivating Endothelial Intercellular Adhesion Molecule-1
Purpose: Epidermal growth factor-like 7 (EGFL7) has been implicated in various cancers, but its role in different stages of prostate cancer (PCa), particularly metastatic castration-resistant prostate cancer (mCRPC), remains unclear. This study aimed to investigate the biological function of EGFL7…
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Journal Article
Exploring the Causal Association between Erectile Dysfunction and Brain Cortical Structure: Insight from a Bidirectional Mendelian Randomization Study and Cross-Sectional Neuroimaging Study
Purpose: This study aims to investigate the bidirectional causal relationship between erectile dysfunction (ED) and cerebral cortical structure. Materials and Methods: This study employed bidirectional two-sample Mendelian randomization (MR) framework. Exposure and outcome data were derived from…
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Journal Article
Intravesical Cannabidiol for Inflammation and Pain in Interstitial Cystitis/Bladder Pain Syndrome via TLR4/NF-κB and TRPV1 Modulation
Purpose: This study explored the anti-inflammatory and analgesic mechanisms of intravesical cannabidiol (CBD) in cyclophosphamide (CYP)-induced interstitial cystitis/bladder pain syndrome (IC/BPS) rats. Materials and Methods: Female Sprague-Dawley rats were divided into four groups of control…
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Journal Article
Development of a Noble On-Site Dual Screening System for Male Fertility of Sperm Count and Hyaluronidase Activity
Purpose: To develop a noble on-site dual screening system for sperm concentration and hyaluronidase (HAdase) activity of male fertility based on lateral-flow assay methods, and to evaluate the effectiveness of this dual screening system. Materials and Methods: A chromogenic reaction for sperm count…
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Journal Article
Mendelian Randomization Analysis Reveals Iron as a Potential Contributor to Male Infertility
Purpose: This study explores whether certain trace elements are genetically linked to male infertility by using large-scale genetic data and a method called Mendelian randomization (MR), which helps infer causal relationships. Materials and Methods: We obtained genetic data related to trace…