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Frontiers in Pediatrics
Scopus
ISSN 2296-2360 · Frontiers Media S.A. · 13,205 articles in the index
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Journal Article
Case Report: Complete Kawasaki disease in a 2-month-old infant without coronary involvement
BackgroundKawasaki disease (KD) is a systemic vasculitis, of unknown etiology, that usually occurs in children between the ages of six months and five years. Patients at the extremes of ages rarely meet all the clinical criteria required for the diagnosis of KD. Atypical or incomplete presentation…
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Journal Article
Implementation of a nursing- and respiratory therapist-led high-flow nasal cannula pathway is associated with decreased ICU length of stay in bronchiolitis
Background and objectivesBronchiolitis is a leading cause of pediatric intensive care unit (PICU) admission, with increased utilization of high-flow nasal cannula (HFNC) and non-invasive support over time. There is no universally accepted severity measure for patients with critical bronchiolitis…
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Journal Article
Outpatient assessment of bronchopulmonary dysplasia using point of care lung ultrasound
BackgroundLung point-of-care ultrasound (POCUS) is an emerging technology for assessment of neonatal lung diseases. Prior studies have described lung ultrasound scores (LUS) in bronchopulmonary dysplasia (BPD). However, few have assessed LUS in patients with BPD beyond the initial neonatal…
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Journal Article
Macrolide-resistant Mycoplasma pneumoniae in children: clinical features, treatment response, and outcomes in a retrospective cohort from China
IntroductionMacrolide-resistant Mycoplasma pneumoniae (MRMP) has reached extremely high prevalence among children in Asia. However, genotype -phenotype correlations and their impact on clinical outcomes in pediatric community-acquired pneumonia (CAP) remain insufficiently characterized in many…
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Journal Article
Risk of drug-related aggression in pediatric populations: a pharmacovigilance analysis using the FAERS database
BackgroundAggression in pediatric populations poses significant risks to mental health and development, and drug-associated aggression may either exacerbate pre-existing behavioral problems or arise de novo following medication exposure. Existing studies, primarily based on randomized controlled…
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Journal Article
Family matters: the role of parents in adolescent motivation and exercise promotion
ObjectivesThis study aimed to investigate the relationship between parents' exercise habits (PEH), exercise motivation (EMO), and exercise behavior (EB) among junior high school students in Shanghai, with a particular focus on the mediating effects of different types of motivation.MethodsA…
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Journal Article
Congenital pseudarthrosis of the proximal tibia: a case report
Congenital pseudarthrosis of the tibia (CPT) is a rare and challenging pediatric orthopedic disorder that predominantly affects the distal or middle third of the tibia, with involvement of the proximal third being exceedingly rare. Literature on this condition remains limited. This case presents…
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Journal Article
Beyond anti-VEGF: expanding the therapeutic horizon and biomarker landscape in retinopathy of prematurity
BackgroundRetinopathy of prematurity (ROP) remains a leading cause of childhood blindness worldwide. While anti-VEGF therapy has revolutionized ROP treatment, concerns regarding systemic absorption, potential neurodevelopmental impacts, and late reactivation have spurred the quest for alternative…
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Journal Article
Evaluation of the classification performance and cost-effectiveness of classification criteria in children with systemic lupus erythematosus
BackgroundChildhood-onset systemic lupus erythematosus (cSLE) is a chronic autoimmune disease. In Latin America, the utility of the existing lupus classification criteria and their economic implications remain unexplored.ObjectiveTo evaluate and compare the utility and cost-effectiveness of the…
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Journal Article
Artificial intelligence for patent ductus arteriosus—a systematic review
IntroductionOptimal management of patent ductus arteriosus (PDA) remains controversial. Complexity in severity appraisal, high-dimensional data, and the need for longitudinal, individualized assessment make PDA a compelling candidate for Artificial Intelligence (AI)-driven approaches. This…
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Journal Article
A case report of Behcet's disease in a child with trisomy 8 and literature review
ObjectiveReport a case of Behcet's disease (BD) in a child with trisomy 8 mosaicism (T8M), providing insights for the diagnosis, treatment, and prognosis of this condition.MethodsThe clinical data of an 11-year-old girl with T8M mosaicism and BD who was admitted to our hospital in August 2022 were…
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Journal Article
A clavicular overuse injury in a teenage male gymnast: a rare case report
Overuse injuries are frequent in young athletes, particularly in gymnasts. However, physeal injuries of the medial clavicle remain exceptionally rare. We report an unusual case highlighting the diagnostic value of magnetic resonance imaging (MRI). A 12.5-year-old male gymnast presented with…
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Journal Article
Case Report: Newly discovered ELN gene mutation in congenital heart disease: case analysis and review
IntroductionSupravalvular aortic stenosis (SVAS) is a rare left ventricular outflow tract obstruction, most commonly caused by pathogenic variants in ELN. Truncating variants in exons 1–29 typically produce non-syndromic SVAS through elastin haploinsufficiency, whereas C-terminal variants are…
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Journal Article
Elastic stable intramedullary nailing alone for unicameral bone cysts of the humerus in children: a mid-term follow-up study
IntroductionUnicameral bone cyst (UBC) is a common disease in children. There are several different treatment modalities for this condition. Elastic stable intramedullary nail (ESIN) insertion alone was a minimally invasive method that allows for cyst drainage and fracture prevention; however, the…
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Journal Article
Tacrolimus-induced reversible posterior leukoencephalopathy syndrome in a child with nephrotic syndrome: a case report
BackgroundTacrolimus is widely used as an immunosuppressant in the management of refractory nephrotic syndrome. Although effective, it may occasionally lead to rare but serious adverse effects such as posterior reversible leukoencephalopathy syndrome (PRES). PRES has traditionally been associated…
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Journal Article
Comparison of presentation, treatment and follow-up outcomes in first and second wave cohorts of multisystem inflammatory syndrome in children
ObjectiveMultisystem inflammatory syndrome (MIS-C) is life-threatening complication of coronavirus disease 2019 (COVID-19) in children. The objective of this study is to compare the clinical features, and follow-up results of MIS-C patients between the first and second waves of the…
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Journal Article
Development and validation of a predictive nomogram for early detection of necrotizing pneumonia in children with refractory Mycoplasma pneumoniae pneumonia
ObjectiveTo identify predictive factors for necrotizing pneumonia (NP) in children with refractory Mycoplasma pneumoniae pneumonia (RMPP) and develop a predictive nomogram.MethodsA retrospective analysis was conducted on clinical data of children with RMPP admitted to the Affiliated Women and…
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Journal Article
An etiopathogenesis of juvenile idiopathic arthritis: the protein-homeostasis-system hypothesis
The initiation of juvenile idiopathic arthritis (JIA) may be associated with an infection caused by unidentified pathogens. The prevalence or incidence rates of JIA differ markedly among populations. The constituent of microbiota of human species is influenced by age during childhood and differs…
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