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Biomedicine Hub, Pp 1-25 (2026)
ISSN 2296-6870 · Karger Publishers · 142 articles in the index
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Journal Article
Impact of Rurality on Access to Care in Adult Patients with Sinonasal Squamous Cell Carcinoma
Introduction: Social determinants of health (SDOH), such as uninsured, race/ethnicity, and low-income status have been identified as risk factors impacting access to care and survival in sinonasal malignancies. Other SDOHs, including rurality and distance to adequate healthcare, have increasingly…
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Journal Article
Novel Insights Occult Tuberculosis in Dialysis Patients is rarely straightforward Retrospective Case Series.
The diagnosis of tuberculosis (TB) in dialysis patients may be difficult because of the increased frequency of extra-pulmonary presentations, atypical clinical manifestations, and non-specific symptoms. This study aimed to investigate the spectrum of clinical presentations and outcomes of…
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Journal Article
Dysphagia and Dysphonia in Parkinson’s Disease: Pathophysiological Mechanisms, Treatment Approaches, and Clinical Implications
Parkinson’s Disease (PD) is a progressive neurodegenerative disorder characterized by the degeneration of dopamine-producing neurons, leading to a wide range of symptoms that significantly impact patients’ quality of life. Among these, dysphagia (difficulty swallowing) and dysphonia (voice…
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Journal Article
Efficacy and safety of pioglitazone in improving cognitive function among patients with impaired cognition as an add on therapy- a study protocol.
Rationale Management strategy to improve cognition is one of the challenges faced by clinicians. Importantly, pioglitazone, a safe and cost-effective medication has been shown to improve memory dysfunction in both animal and some clinical studies Aim To assess and compare the effect of pioglitazone…
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Journal Article
Respiratory and Cardiovascular Readmissions and Prescription Patterns after Spinal Cord Injury: A National Registry-Based Study from Sweden
Introduction: Spinal cord injury (SCI) is associated with increased risk of cardiovascular and respiratory morbidity, which are major contributors to rehospitalization and mortality. While overall rehospitalization after SCI is well documented, few studies have focused specifically on early…
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Journal Article
Cecoureterocele Presenting as a Urethral Mass in an Infant Female: A Rare Case Report
Introduction: Cecoureterocele is an uncommon variant of ureterocele characterized by submucosal extension of the ureterocele beyond the bladder neck into the urethra. It is usually associated with duplex collecting systems and is more commonly encountered in pediatric female patients. Clinical…
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Journal Article
Assessing the Reliability of Lung Ultrasound in Neonatal Acute Care Setting: A Systematic Review Protocol
Introduction: Choosing appropriate diagnostic imaging modalities in neonates is often challenging. Lung ultrasound (LUS) has been increasingly adopted in the diagnosis and monitoring of respiratory diseases in this population. However, since LUS interpretation relies heavily on operator skills and…
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Journal Article
Testicular Puncture and Aspiration as an Intraoperative Adjunct in Pediatric Testicular Torsion: A Case Report with Long-Term Follow-Up
Introduction: Assessing testicular viability during surgical exploration of an acute scrotum is challenging, especially when the testis appears discolored. The decision between orchiectomy and orchiopexy often relies on subjective intraoperative judgment. We report a case in which testicular…
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Journal Article
Anti-Inflammatory and Neuroprotective Effects of a Novel Water-Soluble Formulation of Coenzyme-Q10 and Ashwagandha Root Extract in a Paraquat-Induced Rat Model of Parkinson’s Disease
Introduction: Parkinson’s disease (PD) is characterized by progressive loss of dopaminergic neurons in the substantia nigra resulting in impaired movement coordination. There is no cure, and current therapies only provide symptomatic relief and have adverse side effects over long-term use. There…
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Journal Article
A Rare Case of Calciphylaxis: A Case Report
Introduction: Calciphylaxis is a rare and severe disorder characterized by obstructive small vessel disease in the subcutaneous adipose tissue and skin, leading to necrotic skin lesions. The condition poses a significant risk of mortality due to infectious and ischemic complications. Case…
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Journal Article
Neuroimaging-Based Responses to Blood Pressure Augmentation in Acute Ischaemic Stroke: A Systematic Review
Introduction: In acute ischaemic stroke, the key treatment to reduce infarct growth is reperfusion, achieved through thrombolysis, endovascular thrombectomy, or endogenous reperfusion. Prior to definitive reperfusion therapy, blood pressure augmentation may enhance cerebral perfusion and reduce…
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Journal Article
Central Diabetes Insipidus in Father and Son Linked to a Rare Variant: A Case Report
Introduction: Central diabetes insipidus (CDI) is a rare disorder caused by a deficiency in the secretion of arginine vasopressin (AVP) from the posterior pituitary. It can be either acquired or congenital, often due to genetic factors, and is typically inherited in an autosomal dominant manner…
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Journal Article
Anti-Glomerular Basement Membrane Disease without Linear IgG Deposits in an Elderly Patient with Metastatic Rectal Cancer: A Case Report
Introduction: Anti-glomerular basement membrane (anti-GBM) disease is classically diagnosed based on presence of rapidly progressive glomerulonephritis, circulating anti-GBM antibodies, and the hallmark finding of linear IgG deposition along the glomerular basement membrane on kidney biopsy. These…
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Journal Article
Negative Results in Neonatal Trials: Clinical Lessons and Future Directions – A Narrative Review
Background: Clinical research involving neonates often presents unique ethical and practical challenges. These difficulties may lead to the early termination of clinical trials, particularly when negative or inconclusive results occur, contributing to publication bias. Failure to report such…
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Journal Article
Burning Mouth Syndrome and the Oral Microbiome: Unveiling Potential Links
Background: Burning mouth syndrome (BMS) is a chronic neuropathic orofacial pain condition that remains challenging to manage due to its unclear etiology and limited treatment options. While multiple systemic factors have been proposed, emerging evidence suggests that oral microbial dysbiosis may…
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Journal Article
Differential Expression of Micro-RNA in Maternal Blood of Pregnancies Affected with Late-Onset Fetal Growth Restriction
Introduction: Micro-RNAs (miRNAs) participate in different biological processes, including fetal hypoxia. In this work, we aimed to evaluate the existence of a miRNA differential expression profile in maternal blood of pregnancies affected with late-onset fetal growth restriction (LO-FGR). Methods…
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Journal Article
Postmortem Inductively Coupled Plasma Mass Spectrometry Analysis Reveals Elevated Heavy Metal Concentrations in Coronary Arteries: A Comparative Autopsy Study Supporting a Toxic Inflammatory Hypothesis for Atherosclerosis
Introduction: A large number of studies have been carried out for the etiology of atherosclerosis and many risk factors have been identified, including environmental factors and heavy metals, which are related to the pathogenesis. This study aimed to determine the effects of heavy metals, which…
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Journal Article
The Splash Zone: Efficacy of Ureteroscopic Adapters in Containing Hazardous Leak
Introduction: Ureteroscopic procedures pose a splash hazard to urologists from irrigant contaminated with urine, blood, or caustic substances, risking health and vision. While ureteroscopic adapters aim to minimize fluid leakage, their efficacy remains unstandardized, with high-pressure irrigation…
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Journal Article
Routine Use of Analgesia for Venipuncture in a Tertiary Level Neonatal Intensive Care Setting: A Quality Improvement Study
Introduction: Neonatal exposure to pain can lead to altered pain perception in later years of life. Despite the availability of measures to alleviate pain, routine use is lacking. We decided to conduct a quality improvement (QI) study to increase the use of analgesia during venipuncture, a common…
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Journal Article
MedReadr: Development and Evaluation of an In-Browser, Rule-Based Natural Language Processing Algorithm to Estimate the Reliability of Consumer Health Articles
Introduction: The internet is a major source of medical information for patients, yet the quality of online health content remains highly variable. Existing assessment tools are often labor-intensive, invalidated, or limited in scope. We developed and validated MedReadr, an in-browser, rule-based…