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Frontiers in Cardiovascular Medicine
Scopus
ISSN 2297-055X · Frontiers Media S.A. · 14,936 articles in the index
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Journal Article
Gender disparities in heart failure diagnosis and management: under the radar
Heart failure (HF) remains a leading cause of morbidity and mortality worldwide, affecting women and men in nearly equal numbers, yet important sex- and gender-related differences remain insufficiently recognized in clinical practice and research. Biological sex and gender influences profoundly the…
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Journal Article
Impact of the society for vascular surgery/society of thoracic surgeons classification on prognosis and therapeutic strategies in acute Stanford type A aortic dissection
ObjectiveThe Stanford classification does not differentiate between antegrade and retrograde primary entry tears in acute Stanford type A aortic dissection (ATAAD). The 2020 Society for Vascular Surgery/Society of Thoracic Surgeons (SVS/STS) classification categorizes ATAAD into SVS/STS-A and…
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Journal Article
Case Report: Hypertensive encephalopathy presents with complex types of sleep breathing events
BackgroundObstructive sleep apnea (OSA) is a common sleep disorder and one of the common causes of secondary hypertension. Patients with this condition often have characteristics such as reverse spoon-shaped blood pressure patterns and poor response to multiple drug treatments. Patients often…
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Journal Article
Proteomic and genetic predictors and risk scores of cardiovascular diseases in persons living with HIV
BackgroundCardiovascular disease (CVD) prediction models for persons living with HIV (PLWH) depend on traditional CVD risk factors, but these underestimate true risk. We aimed to identify proteins and genetic variants and create proteo-genomic risk scores for CVD in PLWH.MethodsWe analyzed genetic…
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Journal Article
The global, regional, and national burden of non-rheumatic degenerative mitral valve disease from 1990 to 2021 and forecast for 2050
BackgroundGiven the changing epidemiological and burden trends of non-rheumatic degenerative mitral valve disease (DMVD), it is crucial to re-examine geographical differences and trends. Here, we describe the current trends of DMVD epidemiology using data from the Global Burden of Diseases (GBD)…
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Journal Article
Insulin resistance with associated hyperinsulinemia as a risk factor for the development and worsening of HFpEF
The prevalence of insulin resistance (IR) with associated hyperinsulinemia (HI) is increasing worldwide, as is the prevalence of heart failure with preserved left ventricular ejection fraction (HFpEF). This narrative review aims to explore the epidemiological and pathophysiological relationship…
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Journal Article
Qing-Xin-Jie-Yu granule prevents myocardial infarction-induced apoptosis via inhibition of p38 MAPK pathway
Background and aimMyocardial infarction (MI) is a leading cause of death globally, and traditional Chinese medicine (TCM) offers therapeutic potential through its multi-targeted approach. This study aims to investigate the protective mechanisms of Qing-Xin-Jie-Yu Granule (QXJYG) against…
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Journal Article
Comparing TAVR + PCI vs. SAVR + CABG across short- and mid- to long-term horizons in patients with severe aortic stenosis and concomitant CAD: a systematic review and meta-analysis
BackgroundThe optimal revascularization approach for intermediate- and high-risk individuals with severe aortic stenosis (AS) and concomitant coronary artery disease (CAD) remains uncertain, particularly regarding the comparative short- and mid- to long-term outcomes of transcatheter aortic valve…
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Journal Article
Nonlinear HbA1c thresholds reveal accelerated atherogenic remodeling and improved risk reclassification in type 2 diabetes
Dysglycemia, lipid metabolism, and cardiovascular disease (CVD) progression in type 2 diabetes (T2D) are closely interconnected, yet the non-linear lipid remodeling processes underlying atherogenic dyslipidemia remain insufficiently defined. This study aimed to identify HbA1c thresholds associated…
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Journal Article
Reliability of B-mode ultrasound measurement of carotid intima-media thickness in assessing cardiovascular risk: a cross-sectional study
ObjectiveCarotid intima-media thickness (CIMT) is considered a marker of subclinical atherosclerosis; however, its reliability in predicting cardiovascular risk across different populations remains controversial. This study aimed to evaluate the correlation between B-mode ultrasound-measured CIMT…
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Journal Article
Serum-Amyloid-A to High-Density-Lipoprotein-Cholesterol Ratio: superior biomarker for early diagnosis of coronary artery disease with clinically relevant stenoses and development of machine learning diagnostic model
BackgroundThis study aimed to evaluate the early diagnostic value of Serum-Amyloid-A to High-Density-Lipoprotein-Cholesterol Ratio (SHR) for coronary artery disease (CAD) with clinically relevant stenoses and develop a machine learning diagnostic model based on eXtreme Gradient Boosting…
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Journal Article
Analysis of risk factors for calf muscular vein thrombosis in elderly patients with acute exacerbation of chronic obstructive pulmonary disease
ObjectiveThis study aimed to identify the independent risk factors for calf muscular vein thrombosis (CMVT) in elderly patients experiencing an acute exacerbation of chronic obstructive pulmonary disease (AECOPD).MethodsA retrospective study was conducted involving 128 elderly patients (age ≥60…
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Journal Article
Assessing the impact of transcatheter edge-to-edge repair on reverse remodeling in secondary mitral regurgitation: a systematic review and meta-analysis
Background and aimTranscatheter edge-to-edge repair (TEER) is a minimally invasive approach to reduce secondary mitral regurgitation (SMR) in patients with heart failure. However, there is limited evidence on its effectiveness in achieving reverse remodeling. Our aim was to assess the effects of…
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Journal Article
The application of coronary CT angiography combined with dynamic electrocardiogram in the diagnosis of myocardial ischemia in coronary heart disease
ObjectiveThis study aims to analyze the diagnostic methods for myocardial ischemia in coronary heart disease and compare the diagnostic performance of coronary CT angiography (CCTA), dynamic electrocardiogram (DCG), and CCTA-DCG.MethodsThis study retrospectively selected 300 patients who underwent…
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Journal Article
POEMS syndrome with cardiovascular lesions as the initial manifestation: a case report and literature review
Polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, and skin changes (POEMS) syndrome is frequently mistaken for chronic inflammatory demyelinating polyneuropathy, as its clinical profile is highly variable and neurological symptoms often dominate the initial course. In the present…
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Journal Article
A modifiable imaging biomarker: epicardial adipose tissue density in ischemia with non-obstructive coronary arteries
BackgroundThe impact of epicardial adipose tissue (EAT) on the risk of non-obstructive coronary artery disease (CAD) remains unclear. This study aims to investigate the association between EAT and ischemia with non-obstructive coronary arteries (INOCA).MethodsThis study enrolled 281 patients with…
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Journal Article
Nomogram prediction model for pneumonia after valve replacement in patients with heart valve disease
BackgroundPatients with heart valve disease (VHD) combined with pulmonary hypertension (PH) have a higher risk for hospital-acquired pneumonia. We aimed to analyze the risk factors and construct a valid nomogram model for predicting hospital-acquired pneumonia among those patients.MethodsPatients…
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Journal Article
Promises and challenges of AI-enabled methods for myocardial characterisation in cardiovascular magnetic resonance
Cardiac magnetic resonance (CMR) tissue characterisation is central to the diagnosis and risk stratification of myocardial disease. However, for certain techniques tissue characterisation CMR is limited by reliance on contrast agents, sensitivity to motion, prolonged acquisition times, and time-…
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Journal Article
Delayed complete atrioventricular block 11 months after transcatheter aortic valve replacement in a patient with a short membranous septum: a case report
Conduction disturbances are among the most frequent complications of transcatheter aortic valve replacement (TAVR), typically occurring within the first 72 h after implantation. However, delayed complete atrioventricular (AV) block is rare and may present late with serious clinical consequences. We…
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Journal Article
Identification and functional analysis of differential miRNAs in young and middle-aged adults with essential hypertension: exploring potential biomarkers and therapeutic targets
BackgroundEssential hypertension (EH) in young and middle-aged adults is a major risk factor for cardiovascular morbidity, yet the detailed molecular mechanisms underlying this condition have not been fully understood. MicroRNAs (miRNAs) have emerged as critical regulators of gene expression and…
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