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Russian Open Medical Journal
Scopus
ISSN 2304-3415 · Limited liability company «Science and Innovations» (Saratov) · 628 articles in the index
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Journal Article
The Effect of Smoking, Gender and Histological Type of Cancer on Body Mass Index in Lung Cancer Patients: A Cross-Sectional Study
Objective — This study aimed to investigate the association of smoking status, gender, cancer histological subtype and stage with body mass index (BMI) in patients with lung cancer. Methods — Our cross-sectional study was conducted on 400 patients with histologically confirmed lung cancer at…
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Journal Article
Boosting Antitumor Activity: CuO Nanoparticles Enhance Pemetrexed Efficacy and Increase hsa-miR-548c-3p Expression in Human Lung Cancer
Background and objective — Lung cancer, particularly non-small cell lung cancer (NSCLC), is a leading cause of cancer-related death. Pemetrexed (PEM) is recognized as an effective chemotherapy drug. However, its efficacy is often compromised by resistance and side effects. Copper oxide…
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Journal Article
Morphological Characteristics of the Thymus in Opisthorchiasis
Opisthorchiasis is a widespread parasitic disease in the Ob and Irtysh River basins in Russia, characterized by a prolonged course in humans and carnivorous animals, which are the definitive hosts. The impact of this parasitic disease on age-related morphological changes of the thymus remains an…
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Journal Article
Development of the Health Office Management Information System (SIM-DINKES) to Support Digital Transformation
Background — In recent years, digital transformation has become a key strategy for enhancing the efficiency, transparency, and quality of data utilization in the healthcare sector. Currently, this process is being implemented in Badung Regency (Bali Province) through the Health Office Management…
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Journal Article
Principles of Bioethics through the Lens of the Uzbek National Mentality: An Exploratory Survey of Online Respondents
Introduction — Bioethics provides the normative foundations for contemporary medical practice; however, the interpretation and application of its core principles (confidentiality, truth-telling, and informed consent) are largely determined by context. Although these principles are widely recognized…
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Journal Article
Cognitive Performance in Adolescent Boys with and without Obesity and Obstructive Sleep Apnea-Hypopnea Syndrome: A Pilot Study
Objective — This pilot study aimed to examine how cognitive performance of obese and nonobese adolescent boys with obstructive sleep apnea-hypopnea syndrome (OSAHS) is associated with anthropometric parameters and OSAHS-related indicators. Material and Methods — The study included 35 obese and 20…
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Journal Article
The Effect of Geographic Region on Stone Composition and Treatment Outcomes for Urolithiasis in Kyrgyzstan
Background — Data on urolithiasis characteristics and treatment outcomes in high-elevation areas are limited. Using computed tomography (CT), we assessed whether kidney stone composition, CT density, and minimally invasive treatment outcomes differ between residents of Kyrgyzstan living in…
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Journal Article
The Effect of Nano-Selenium and Lactobacillus Casei on Hormonal, Biochemical and Hematological Parameters of Male Syrian Mice after Irradiation
Background — Nano-selenium and probiotics can be used as suitable radiation protective agents to reduce the effects of radiation. Objective — The goal of this study was to investigate the role of nano-selenium and probiotics as radioprotectors for the reproductive system against the effects of…
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Journal Article
Increased Plasma Mitochondrial DNA Copy Number and Association with Complications after Coronary Artery Bypass Grafting: Results of a Pilot Cohort Study
Objective — To determine the mitochondrial DNA (mtDNA) copy number in the blood of patients before and within 10 days after coronary artery bypass grafting (CABG) and to evaluate the association between mtDNA copy number and postoperative complications. Methods — This single-center, prospective…
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Journal Article
The Effect of Alkylglycerol Ethers on Anxiety
Objective — To evaluate the potential of alkylglycerol ethers (AGEs) for enhancing behavioral models. Methods — AGEs for the experiment were isolated from the digestive gland of the gonad squid (Berryteuthis magister) and purified using conventional methods. The AGE composition was determined by…
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Journal Article
Determining the Role of Emotional Intimacy and Sexual Attitude in Predicting Sexual Satisfaction with the Mediating Role of Hedonism and Sensation Seeking in Childless Married Women
This study aimed to determine the role of emotional intimacy and sexual attitude in predicting sexual satisfaction, with the mediating role of hedonism and sensation seeking among childless married women in Kazeroon County. Material and Methods — This study was descriptive and correlational in…
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Journal Article
Characteristics of Clinically Non-Functioning Pituitary Adenomas in Basra
Background — Non-functioning pituitary adenoma (NFPA) is a benign tumor that does not secrete excess hormones but can cause a mass effect. Objective — This study evaluated the clinical characteristics, treatment methods, complications, and outcomes of patients with NFPAs at the Faiha Specialized…
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Journal Article
Psychoemotional Contribution to the Development of Mental Fatigue in Women vs. Men: A Comparative Study of Two Cognitive Load Types
The objective of this study was to comparatively examine the effects of different cognitive load types on the development of mental fatigue, taking into account psychoemotional state and gender differences. Methods — The experiment enrolled 35 volunteers (57% women, 43% men). Mental fatigue was…
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Journal Article
Taraxasterol Exerts Cytoprotective Effects Against Nicotine Toxicity in Leydig (TM3) and Sertoli (TM4) Cell Lines
Rationale — The male reproductive system is an organ sensitive to toxins, and nicotine exposure is recognized as a detrimental factor for male sexual function. Taraxasterol, a bioactive compound with antioxidant and antiapoptotic properties, has potential protective effects against cytotoxicity…
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Journal Article
Factors Determining the Implementation of Shared Decision-Making Principles in Family Planning Counseling: A Scoping Review
Shared decision-making (SDM) is a collaborative approach to healthcare that integrates patient preferences with health care provider expertise to improve the quality of decisions. In family planning, SDM is critical to tailoring contraceptive methods to individual needs. This scoping review…
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Journal Article
Use of Serum Cortisol, Plasma Corticotropin, and Serum Dehydroepiandrosterone Sulfate Levels in the Diagnosis of Hypothalamic-Pituitary-Adrenal Insufficiency
Background — There is no single test that can definitively diagnose hypothalamic-pituitary-adrenal (HPA) insufficiency (HPAI). The goal of our study was to evaluate the effectiveness of measuring serum cortisol, serum dehydroepiandrosterone sulfate (DHEA-S), and plasma corticotropin (ACTH) levels…
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Journal Article
Dynamics of Stress Biomarker Levels and Their Relationship with Psychological Characteristics of Healthcare Workers during the implementation of a Program for Reducing Occupational Burnout
Objective — The aim of this study was to examine the dynamics of stress biomarkers and their association with psychological characteristics in healthcare workers during a pilot implementation of a program for reducing occupational burnout. Material and Methods — Physicians and nurses (n=20) from…
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Journal Article
Successful Combination Treatment by Repeat Autologous Cell Therapy in a Young Patient with Dilated Cardiomyopathy
Dilated cardiomyopathy (DCM) is one of the leading causes of heart failure (HF). Considering the rapidly progressive course of this difficult-to-treat disease and the frequency of decompensation (especially among young patients), DCM poses a significant challenge to the healthcare system. We…
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Journal Article
Association of Echocardiographic Parameters with Nitric Oxide Levels in Overweight Patients with Coronary Artery Disease after Coronary Artery Bypass Grafting
Introduction — Overweight and obesity are recognized as significant risk factors for adverse outcomes after coronary artery bypass grafting (CABG). One of the key mechanisms linking obesity to the progression of cardiovascular pathology is endothelial dysfunction, marked by reduced nitric oxide…
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Journal Article
Prospects for Combination Antiarrhythmic Drug Therapy in Cardiology: Is It Time for a Polypill?
In this article, we discuss the feasibility of combination antiarrhythmic drug therapy in the form of a polypill. In our opinion, this type of treatment is currently limited by various factors discussed in this article. Large-sample studies are needed to evaluate the efficacy and safety of…