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Advancements in Life Sciences
Scopus
ISSN 2310-5380 · The Running Line · 112 artikel di indeks
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Artikel Jurnal
Neutropenic fever in patients with Hematologic Malignancies: Microorganisms and antimicrobial susceptibility
Background: Neutropenic fever is a life-threatening complication for patients with hematological malignancies during the course of their management. Early and precise detection of causative microorganisms are crucial. The purpose of this study was to identify the spectrum of these microorganisms…
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In Silico Analysis of CYP1B1 Gene Mutations in Pakistani Families Reveals Structural and Functional Characteristics
Background: Mutations in the CYP1B1 gene have been associated with primary congenital glaucoma (PCG), a developmental visual disorder. CYP1B1 mutations have been linked to increased lipid peroxidation and abnormalities in trabecular meshwork. In this study, protein modeling was utilized to analyze…
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Diabetic Peripheral Neuropathy: Navigating Controversies and Pioneering Advances
This review examines Diabetic Peripheral Neuropathy (DPN), a significant complication of diabetes affecting nearly half of diabetic patients. DPN is crucial to understand due to its high prevalence and profound impact on patients' quality of life, causing pain, sensory loss, motor dysfunction, and…
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Improving the nutraceutical content of tomato (Lycopersicon esculentum) by advanced environmental conditions and agricultural practices
The consumption of tomatoes has been associated with diminishing the risk of several lethal diseases, e.g., heart attack and cancer. This is because tomato contains high antioxidants that have been shown to protect against oxidative damage in numerous empirical and epidemiological studies…
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Phytochemistry and pharmacology potential of Lippia javanica: a bibliometric and systematic review
Lippia javanica (Burm. f.) is an African plant with numerous ethnomedicinal uses, including asthma, tuberculosis, colds, influenza, pneumonia, coughs, and dermatitis treatments. Many of the ethnomedicinal properties and folkloric claims about the plant have since established by numerous scientific…
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Understanding the Role of Genetics in Tumour and Cancer Biology
The interplay between genetics and cancer has been a focal point of research for decades, leading to profound understandings into the molecular mechanisms driving tumorigenesis. In this comprehensive review article, we explore the genetic basis of cancer, encompassing the diverse array of…
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The Effects of Neurotoxic Insecticides on Insect Antioxidant System Parameters: A Mini-Review
The resistance of insects to insecticides is one of the most pressing problems of our time. The study of resistance mechanisms is an important link in addressing a whole range of fundamental and practical problems of modern biology. The long-term and intensive use of insecticidal products was…
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In silico advancement of Aspergillus niger gluconic acid hyperproduction recommends plans for switching acid productivity
Background: Non-toxic, non-volatile organic acid, gluconic acid (pentahydroxycaproic acid) is found in abundance in honey and plants and in wines. Gluconic acid and its salts are used widely in food, feed, pharmaceuticals, textiles, and many other industries. Methods: In the current investigation…
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Study on the role of gold and silver nanoparticles on antibacterial activity and lung cancer cell line (A549)
Background: This study will evaluate gold and silver nanoparticles' antibacterial action against Staphylococcus aureus and Pseudomonas aeruginosa and synergistic effects on the human lung epithelial cell line A549. Methods: Gold and silver nanoparticles (33-40 nm) were obtained from Nanomaterials…
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Investigating the Association Between Vitamin D and Anti-Thyroid Peroxidase Antibodies in Hypothyroid Iraqi Patients
Objective: The aim of this study was to investigate the relationship between vitamin D quantities and anti-thyroid peroxidase antibodies (anti-TPO) in Iraqi hypothyroidism patients and healthy individuals, using statistical analyses including the Cs-T, t-test, and P-values. Methods: This study…
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Artikel Jurnal
Organophosphorus Pesticide Residues Contaminating Vegetables and Fruits in Sudan are a Major Public Health Hazard
Background: Organophosphorus pesticides (OP) are a diverse group of compounds. Extensive application of these chemicals in Sudan increases the risk of food and water contamination. We aimed to identify the occupational hazard on sellers and consumers resulting from exposure to organophosphorus…
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Efficacy of autogenic, allogenic and heterogenic platelet rich plasma (PRP) on Avulsion skin wounds in rabbit model
Background: Wound healing through second intention was prone to issues. As a result, there is a strong need in veterinary medicine for therapies that hasten the healing of secondary wounds. These studies demonstrate the effect of autogenic, allogenic, and heterogenic PRP on healing of wounds…
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Bone marrow-derived mesenchymal stem cells: a potential therapy in an autoimmune hepatitis rat model
Background: Autoimmune hepatitis (AIH) is becoming more common worldwide. The therapy choices for AIH are still limited, with unfavorable side effects resulting in patients with a low quality of life. This study aims to study the therapeutic role of bone marrow-derived mesenchymal stem cells (MSCs)…
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Prevalence of programmed cell death ligand 1 (PD-L1) Expression among Tumor Samples from Iraqi Patients with Non-Small Cell Lung Cancer
Background: In a subgroup of patients with advanced stage lung cancer, immunotherapy that specifically targets the PD-L1/PD-1 pathway has been demonstrated to enhance survival. Expression of PD-L1 in cancer cells has been recognized as a promising biomarker for predicting the probable response of…
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Artikel Jurnal
Prevalence, Viral Load Dynamics, and Factors Influencing SARS-CoV-2 Infection: A Cross-sectional Study in Lahore, Pakistan
Background: The pandemic caused by novel coronavirus has caused disaster worldwide and impacted the clinical settings with huge burden. The virus presented with diverse patterns of severity and the gold standard testing for corona virus was real-time PCR. Methods: This study aimed to understand the…
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A novel combinatorial approach for the Identification of Cutibacterium namnetense and Cutibacterium modestum from Facial Acne Samples
Background: Cutibacterium spp. is one of the most understudied bacteria and this is owed to its slow growing nature and its stringent requirement for anoxic conditions. To date, shortgun metagenomic sequencing and MALDI-TOF MS are widely used for species detection but, the latter is not able to…
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Artikel Jurnal
Evaluating the Self-Care Efficacy and Needs of Cancer Patients Experiencing Chemotherapy Side Effects
Background: Chemotherapy involves the strategic use of chemotherapeutic agents to manage cancer. While effective, it can harm healthy cells, leading to adverse effects. Our study aims to identify the self-care gaps faced by cancer patients and provide them with the essential knowledge, skills, and…
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Investigating the Antioxidant and Anti-Cancer Properties of Milk Thistle Extract Against the HepG2 Cells
Background: Hepatocellular carcinoma (HCC) is the third among all cancer-related causes of death worldwide. The primary cause of HCC development is oxidative stress. Milk thistle (MT) contains numerous phytochemicals that contain antioxidant and hepatoprotective properties. The goal of this study…
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Detection of multidrug-resistant (MDR) Staphylococcus aureus isolated from raw milk in a dairy farm
Background: The presence of microorganisms in milk cannot be totally prevented, making it a crucial factor in determining its quality. Staphylococcus aureus is one of the germs that can be detected in milk and other dairy products. Many S. aureus related foodborne disease outbreaks have been…
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Artikel Jurnal
In vitro step up NaCl treatment method as inducer of salinity tolerance in Basmati rice varieties
Background: Salt has been recorded to negatively impacts rice crop's seedling and reproductive stages. Globally, soil salinity is 2nd most important abiotic factor, profoundly impacting rice productivity. The purpose of current research is to induce salinity tolerance in salt sensitive varieties of…