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World Journal of Traditional Chinese Medicine
Scopus
ISSN 2311-8571 · Wolters Kluwer Medknow Publications · 344 artikel di indeks
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Artikel Jurnal
Significant Improvement of Hippocampus in Chronic Unpredictable Mild Stress Rats by Ethyl Acetate Extract of Taxus chinensis (Pilg.) Fruit: A New Functional Discovery of A Natural Product
Background: Depression is a neuroimmune disorder marked by inflammation in the cerebral cortex and hippocampus. Taxus Chinensis (Pilg.)Fruit is a natural product known for its anti-inflammatory effects. However, limited research exists on the antidepressant mechanisms of the ethyl acetate extract…
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Artikel Jurnal
Catalpol Confers Neuroprotection against Cerebral Ischemic Injury by Regulating the Phosphatidylinositol 3-Kinase/Protein Kinase B/Glycogen Synthase Kinase 3 Beta/β-Catenin Signaling Pathway
Background: Ischemic stroke is a leading cause of long-term neurological disability worldwide. Within minutes of its onset, blood flow to the brain’s ischemic core drops dramatically, resulting in irreversible damage and eventual neuronal death in the affected area. Currently, effective clinical…
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Artikel Jurnal
Mechanism of Electroacupuncture Pretreatment on M1 Macrophage Polarization in A Rat Model of Primary Dysmenorrhea Based on the Nuclear Factor-κB/Nucleotide-Binding Oligomerization Domain-Like Receptor Protein 3 Pathway
Objective: The objective is to explore the effect of electroacupuncture (EA) on M1 macrophage polarization mediated by the nuclear factor-κB (NF-κB)/nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3) in a primary dysmenorrhea (PDM) rat model. Materials and Methods: A total of…
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Artikel Jurnal
Synergistic Effects of Betula platyphylla and Dictamnus dasycarpus Formulation on T-Cell Regulation and Atopic Dermatitis Treatment
Background: Atopic dermatitis (AD) is a chronic inflammatory skin disease involving T cell activation and elevated IgE levels. Betula platyphylla (BP) and Dictamnus dasycarpus (DD) are traditional medicinal herbs with known anti-inflammatory properties. However, their combined effect on T cell…
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Artikel Jurnal
Shen-Ling-Bai-Zhu Pulvis Improving Glucolipid Metabolism and Insulin Resistance of Rat Models of Pediatric Obesity-Related Type 2 Diabetes Mellitus
Objective: To explore the effects of Shen-Ling-Bai-Zhu pulvis (SLBZ pulvis) on pediatric obesity-related type 2 diabetes mellitus (T2DM) through the animal experimental study based on the Traditional Chinese Medicine (TCM) therapy of “strengthening spleen to resolve phlegm-dampness”. Methods…
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Artikel Jurnal
Chemical Constituent Analysis of Moringa oleifera Leaves Based on High-Performance Liquid Chromatography-Quadrupole Time-of-Flight Tandem Mass Spectrometry/Mass Spectrometry Combined with Molecular Network Technology
Objective: Moringa oleifera Lam. (M. oleifera) leaves are from a high-economic-value crop and exhibit multiple pharmacological effects, such as hypolipidemic and hypoglycemic activities. However, the studies on the pharmacological basis of M. oleifera leaves (MOL) were not complete, and the…
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Artikel Jurnal
Mechanistic Insights into Luteolin’s Effect on Gastric Cancer: Inhibition of MCL1 and Its Impact on PI3K-Akt and JAK-STAT Signaling
Objective: This study investigates the molecular mechanisms by which luteolin (Lu) regulates the PI3K-Akt and JAK-STAT signaling pathways through MCL1, thereby influencing chemotherapy resistance in gastric cancer (GC) cells. Materials and Methods: Network pharmacology was employed to identify…
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Artikel Jurnal
Tian Jing Ze Lan Decoction Improves Ovarian Function in Rats with Polycystic Ovary Syndrome by Regulating the Nrf2/HO-1 Signaling Pathway to Reduce Oxidative Damage
Objective: This study investigated how Tian Jing Ze Lan decoction (TJZL) ameliorates polycystic ovary syndrome (PCOS) by regulating oxidative stress (OS), with the aim of providing additional complementary and alternative treatment options for PCOS. Materials and Methods: Liquid Chromatograph Mass…
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Artikel Jurnal
Kaempferol Inhibits Inflammation via Regulating the PI3K/Akt/Nuclear Factor Kappa B Pathway and Promotes Autophagy by Regulating the PI3K/Akt/Mammalian Target of Rapamycin Pathway to Improve Podocyte Injury Induced By Antibody in Lupus Nephritis
Objective: This study aimed to explore the protective effects of kaempferol against podocyte injury in lupus nephritis (LN) and its underlying mechanism. Materials and Methods: Human podocytes were co-cultured with immunoglobulin G (IgG) from patients with LN (IgG-LN) to simulate podocyte injury in…
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Artikel Jurnal
Serum Pharmacology to Investigate the Active Components and Anti-Inflammatory Mechanism of Lonicera japonica Thunb. and Shuangbei Syrup
Objective: To investigate the mechanism by which Lonicera japonica Thunb. (L. japonica), as a ministerial drug, it assists Shuangbei Syrup in exerting its anti-inflammatory effect. Materials and Methods: First, network pharmacology was used to analyze the anti-inflammatory targets and related…
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Artikel Jurnal
Identification of Active Compounds in Compound Qinlan Oral Liquid Using A Comprehensive Strategy Based on UPLC-Q-TOF-MS, In vitro Activity, and Molecular Docking Techniques
Background: Compound Qinlan oral liquid (CQOL) is a traditional Chinese medicinal formulation with potent anti-inflammatory effects for treating acute bronchiolitis. However, its specific active components and mechanisms of action remain unclear. Objectives: This study aimed to identify potential…
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Artikel Jurnal
Xiebai – A Traditional Food-Medicinal Species
Xiebai is the dried bulb of the perennial plant Xie (Xiaogensuan). As a traditional food-medicinal species, Xiebai meets modern demand for a healthy diet and possesses significant medicinal value. This article systematically discusses the historical basis, distribution, bioactive components, edible…
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Artikel Jurnal
Isolation and Characterization of Antidiabetic Compounds (Flavonoids) and Antioxidant Activity of Leptopus cordifolius (Wall. ex Decne.) Decne. Leaves
Objective: Leptopus cordifolius Wall. ex Decne (L. cordifolius) is used in traditional medicine and has pharmacological properties including antioxidant and antidiabetic actions. However, little is known about the phytoconstituents of L. cordifolius that have antidiabetic properties. Materials and…
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Artikel Jurnal
Animal Models for Traditional Chinese Medicine Syndromes Associated with Hyperuricemia
Hyperuricemia (HUA), which serves as a primary risk factor for gout and is associated with life threatening conditions such as chronic kidney disease and cardiovascular diseases, is increasingly gaining public health attention. In the traditional Chinese medicine (TCM) theory, HUA falls into the…
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Artikel Jurnal
Acupuncture at Danzhong Suppresses Myocardial Ischemic Injury by Reducing Mitochondrial Damage
Objective: This study investigated whether acupuncture at Danzhong can treat ischemic heart disease. Materials and Methods: A rat model of ischemic heart disease was established through the subcutaneous injection of isoproterenol hydrochloride (ISO), followed by acupuncture at Danzhong for 3 weeks…
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Artikel Jurnal
Rapid Discovery, Guided Isolation, and Mechanism Study of Anti-neuroinflammatory Constituents from Glycosmis craibii var. glabra Targeting 5-LOX
Objective: In this study, we aimed to screen and identify potent 5-lipoxygenase (5-LOX) inhibitors in Glycosmis craibii var. glabra extract and elucidate the mechanisms underlying their inhibitory effects. Materials and Methods: A 95% ethanol extract of G. craibii var. glabra was analyzed using an…
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Artikel Jurnal
The Potential Effects and Use of the Proprietary Chinese Medicine Jingfang Granules: Enhancing Immunity by Promoting Energy Metabolism
Objective: Energy metabolism and immune function have beneficial effects on health. In this study, we demonstrated that early intervention with Jingfang granules (JFGs) promoted energy metabolism and immune function by using an eight-channel energy metabolism detection system and metabolomics…
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Artikel Jurnal
Shenfu Injection Mitigates Acute Lung Injury in Experimental Septic Rats Via the Inhibition of Programmed Cell Death Signaling
Objective: Shenfu injection (SFI), derived from traditional Chinese medicine, is commonly used to treat septic shock. Although programmed cell death signaling between macrophages and lymphocytes is known to be activated in sepsis, its role in mediating SFI’s therapeutic effects remains a central…
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Artikel Jurnal
Catgut Embedding Therapy Alleviates Diabetic Cardiomyopathy and Diabetic Nephropathy by Regulating Glycolipid Metabolism and Inhibiting Ferroptosis
Background: Diabetic cardiomyopathy (DCM) and diabetic nephropathy (DN) are serious yet common diabetes complications. The imbalance of glucolipid metabolism is a key mechanism underlying the pathogenesis of DCM and DN. Acupoint Catgut Embedding (ACE), a major form of acupuncture therapy, exerts…
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Artikel Jurnal
Methodology for Studying Cortical Dynamics Underlying Acupuncture Analgesia
Objective: Acupuncture has gained global recognition primarily for its effectiveness in pain relief. Current understanding of its neural regulation mainly covers the spinal cord and subcortical nuclei, with little evidence from the cortical regions. Neural ensembles constitute basic building blocks…