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Southern African Journal of Infectious Diseases
ISSN 2312-0053 · AOSIS · 375 artikel di indeks
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Artikel Jurnal
Assessment of healthcare worker preparedness and health literacy for Marburg virus disease in Nigeria: A cross-sectional study
Background: Marburg virus disease (MVD) poses an emerging threat to Nigeria, particularly following the 2022 outbreak in neighbouring Ghana. With Nigeria already managing Lassa fever and Mpox outbreaks, assessing healthcare workers’ preparedness at viral haemorrhagic disease reference centres is…
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Artikel Jurnal
Factors predicting the outcome of patients admitted with COVID-19 infection at Pietersburg Hospital, Polokwane, Limpopo province
Background: The emergence of the novel coronavirus disease 2019 (COVID-19), in late 2019 in Wuhan City, has led to a global outbreak of COVID-19, culminating in the declaration of a pandemic by the World Health Organization. Objectives: The aim of the study was to evaluate the factors predicting…
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Prescription precision: Evaluating antimicrobial prescription practices in paediatric and neonatal inpatients
Background: There are limited data on antimicrobial prescribing quality in paediatric wards in African hospitals. Objectives: This study aimed to assess the quality of antimicrobial prescribing. Method: We conducted weekly point prevalence surveys (PPSs) (15 March 2025 – 05 April 2025), assessing…
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Artikel Jurnal
Contemporaneous varicella and zoster or disseminated zoster? A diagnostic challenge in an HIV-positive child
Primary infection with Varicella-Zoster virus causes varicella (chickenpox). Thereafter, following reactivation after a period of latency, it can cause zoster (shingles). Simultaneous occurrence of varicella and zoster is rare, particularly in children. Contribution: We describe an 11-year-old…
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Artikel Jurnal
Prevalence, pattern of disease and antimicrobial susceptibility of Candidozyma auris in the greater Pretoria region from 2021 to 2024
Background: Candidozyma auris has emerged as a nosocomial pathogen in South Africa, characterised by multidrug resistance and environmental persistence. Objectives: This study aimed to describe the prevalence, disease patterns, and antifungal susceptibility patterns of C. auris isolates recovered…
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A retrospective review of leprosy diagnosed histopathologically from skin biopsy specimens in central South Africa
Background: Leprosy, caused by Mycobacterium leprae, remains a condition designated by the World Health Organization (WHO) as a neglected tropical disease, despite formal eradication in South Africa. Histopathology is pivotal in the diagnosis of leprosy, particularly in resource-limited settings…
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Artikel Jurnal
Atypical hepatitis B surface antigen escape mutations in an HIV-positive patient in South Africa
A 44-year-old woman with human immunodeficiency virus (HIV), chronic kidney disease and chronic diarrhoea presented with worsening gastrointestinal symptoms and renal impairment. Despite reported adherence, she had HIV viraemia and atypical hepatitis B serology (absence of hepatitis B core antibody…
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Artikel Jurnal
Severe mpox in an immunocompromised, non-traveller South African male
Mpox is a zoonotic orthopoxvirus infection historically linked to being in endemic regions, travel and close physical contact, including within men who have sex with men (MSM) communities. We report a case of severe mpox in a heterosexual man with advanced human immunodeficiency virus (HIV) disease…
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Artikel Jurnal
Hepatitis B immunity and response to booster vaccination in South African students following childhood immunisation
Background: Despite the introduction of hepatitis B virus (HBV) vaccination into the South African Expanded Programme on Immunization in 1995, HBV remains an important occupational risk to healthcare workers and students. Data regarding the duration and level of HBV immunity following childhood…
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Artikel Jurnal
Pandem-ethics: Post-mortem reflection on healthcare worker ethics during the time of coronavirus disease 2019 pandemonium
Background: The coronavirus disease 2019 (COVID-19) pandemic created ethical and legal tension for healthcare workers (HCWs), who had to balance professional obligations with personal safety, family responsibilities and resource limitations. The concept of ‘duty to care’ re-emerged as a contested…
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Artikel Jurnal
Rare case of Colletotrichum coccodes causing chronic fungal keratitis in an elderly female: Diagnostic delay and antifungal resistance
Fungal keratitis is a vision-threatening corneal infection, most commonly caused by Fusarium and Aspergillus. We report a rare case of keratitis caused by Colletotrichum coccodes in an elderly patient with a chronic corneal ulcer refractory to fluconazole. Initial corneal scrapings were negative…
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Artikel Jurnal
Reporting of notifiable medical conditions among emergency department doctors in Gauteng
Background: Surveillance of notifiable medical conditions (NMCs) is vital for a prompt, appropriate response. In South Africa, studies have demonstrated under-reporting of NMCs despite it being mandatory. Emergency departments (EDs) are often the first point of contact for patients with NMCs…
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Artikel Jurnal
Hepatitis C missed diagnostic opportunities: The role of reflex viral load testing in the era of direct acting antivirals, a descriptive South African study from 2017 to 2021
Background: The hepatitis C virus (HCV) testing algorithm used in South African laboratories involves two tests; a serology test to detect anti-HCV antibodies and a confirmatory test to detect the presence of HCV ribonucleic acid (RNA). These tests usually require consecutive blood samples taken at…
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Artikel Jurnal
R263K-associated dolutegravir resistance on tenofovir, lamivudine and dolutegravir: Implications for earlier genotyping and regimen optimisation
A South African woman receiving tenofovir, lamivudine and dolutegravir (TLD) with good adherence, developed virological failure with the integrase mutation R263K. Viral suppression was achieved after rapid intensification to dolutegravir 50 mg twice daily combined with atazanavir with ritonavir…
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Artikel Jurnal
Zimbabwe adverse events following immunisation surveillance system: A descriptive study with COVID-19 vaccine safety updates
Background: A functional national adverse events following immunisation (AEFI) surveillance system is vital for guiding vaccination policies and sustaining public confidence. The system helps ensure safe immunisation delivery, thereby maintaining high delivery vaccine coverage and reducing…
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Artikel Jurnal
Factors associated with Klebsiella pneumoniae colonisation in adults hospitalised in Johannesburg, South Africa
Background: There is a paucity of data on gastrointestinal colonisation with Klebsiella pneumoniae (KPn) in African adults, although it is a known risk factor for developing KPn invasive disease (KPn-ID). Objectives: We investigated the risk factors for KPn gastrointestinal colonisation among a…
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Artikel Jurnal
A bibliometric analysis of the literature on Mycoplasma and Ureaplasma infections
Background: Mycoplasma and Ureaplasma species are understudied opportunistic pathogens that infect humans, animals and plants. These infections are often asymptomatic, which, together with fastidious growth requirements, makes them challenging to detect. Aim: The review aimed to provide a…
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Artikel Jurnal
‘We are short-staffed’: Dialysis practitioners’ infection prevention and control adherence challenges in the City of Tshwane, South Africa
Background: The burden of infections in dialysis facilities continues to rise worldwide. Due to the invasive procedures associated with haemodialysis (HD), patients undergoing HD in dialysis facilities are at high risk of acquiring bloodstream-related infections. Objective: The present study…
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Artikel Jurnal
Table of Contents Vol 40, No 1 (2025
This Table of Contents reflects the print compilation of peer-reviewed articles published in the journal. Each article listed was originally published online under the journal’s open access model and remains individually accessible and citable. This compilation has been created solely for print…
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Artikel Jurnal
Unexpected non-reactive nontreponemal serology in secondary syphilis: The prozone phenomenon and clinician–laboratory communication
We describe a case of a 22-year-old woman living with human immunodeficiency virus (HIV) who presented with classical features of secondary syphilis. Initial Rapid Plasma Reagin (RPR) testing was unexpectedly non-reactive; however, repeat RPR testing with serum dilution yielded a reactive result…