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Journal of Research in Pharmacy Practice
ISSN 2319-9644 · Wolters Kluwer Medknow Publications · 467 artikel di indeks
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Artikel Jurnal
Prospective Evaluation of Cephalosporin Prescribing and Guideline Adherence in Adult Inpatients at a Tertiary Care Hospital in South India
Objective: This study aimed to assess cephalosporin prescribing patterns, clinical appropriateness, susceptibility and resistance profiles, potential drug–drug interactions, and de-escalation practices in the management of infectious diseases. Methods: This prospective observational study was…
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Artikel Jurnal
Bridging the Gap: Promoting Adverse Drug Reaction Reporting through Innovative Strategies in Zero-reporting Zones at Karaikal – An Educational Intervention Study at Adverse Drug Reaction Monitoring Center
Objective: Adverse drug reactions (ADRs) contribute to morbidity, mortality, compromised quality of life, and increased healthcare costs. Despite various efforts by the regulatory authorities, there remains a problem of underreporting. Our ADR monitoring center was established in JIPMER, Karaikal…
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Artikel Jurnal
Evaluation of Adverse Drug Reactions at Hospital Besut: A 5-year Retrospective Study
Objectives: An adverse drug reaction (ADR) is an unintended and harmful response to a medicinal product and is a significant cause of morbidity and mortality. Despite its importance, no prior systematic ADR evaluation has been conducted at Hospital Besut. This study aimed to analyze ADR patterns…
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Artikel Jurnal
Systematic Review of Bortezomib-based Desensitization Therapy in Sensitized Kidney Transplant Candidates: Efficacy, Safety, and Clinical Outcomes
Objective: Highly sensitized kidney transplant candidates, those with high levels of antihuman leukocyte antigens antibodies, are at increased risk of antibody-mediated graft rejection. The goal of desensitization therapy is to reduce alloantibody titers and increase the chance and success of…
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Artikel Jurnal
Melatonin Supplementation Improves Pain, Sleep Quality, and Total Plasma Antioxidant Capacity in Women with Fibrocystic Breast Disease: A Randomized, Double-blind, Placebo-controlled Trial
Objective: Fibrocystic breast disease (FBD) is a prevalent benign breast disorder primarily affecting women of reproductive age. Characterized by breast pain (mastalgia), cystic and solid breast lesions, and associated hormonal imbalances. Melatonin, a hormone produced by the pineal gland, exhibits…
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Artikel Jurnal
Evaluation of the Efficacy and Safety of the Addition of Lacosamide to Duloxetine in the Treatment of Taxane-induced Peripheral Neuropathy: A Randomized Double-Blind Placebo-Controlled Trial
Objective: Taxane-induced peripheral neuropathy (TIPN) is a frequent and potentially dose-limiting condition. Despite extensive research, there are still no clear guidelines for treating or preventing TIPN, though recent findings indicate that lacosamide may help relieve acute oxaliplatin-induced…
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Artikel Jurnal
Evaluation of the Rational use of Eptifibatide among Patients with Acute Coronary Syndrome Referred to Shahid Chamran Heart Hospital
Objective: This cross-sectional descriptive study was conducted over 3 months (April–June 2025) among acute coronary syndrome (ACS) patients who received eptifibatide at Shahid Chamran Hospital, Isfahan. Methods: Patient demographics, diagnosis, and the chosen therapeutic approach…
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Artikel Jurnal
Effect of Ultra-low-dose Naloxone on Ileus after Cesarean Section: A Randomized Clinical Trial
Objective: Postoperative ileus commonly occurs after abdominal surgeries, often leading to longer hospital stays. While intravenous opioids are effective for pain management, they can extend ileus duration. Ultra-low-dose naloxone presents a promising strategy to improve pain control and minimize…
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Artikel Jurnal
Patients’ Needs and Expectations for the Application of Prevention of Drug-related Problems Prevention Programs
Objective: Drug-related problems (DRPs) constitute a relevant health issue with a significant and escalating impact. The objective of this study is to identify the needs and expectations of patients benefiting from secondary prevention programs for DRPs in an emergency department. Methods: A…
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Artikel Jurnal
Acute Post-cataract Surgery Endophthalmitis and Corneal Ulcer with Acinetobacter Managed with Colistin: A Case Report
Postoperative endophthalmitis is a rare but severe complication of phacoemulsification cataract surgery (PCS). Acinetobacter baumannii is an uncommon pathogen, often associated with multidrug resistance and poor outcomes. In this report, a 73-year-old male who developed endophthalmitis following…
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Artikel Jurnal
Comparison of the Effect of Co-Trimoxazole versus Co-Trimoxazole and Fluoroquinolones in Urinary Tract Infection Prophylaxis in Kidney Transplant Recipients: A Systematic Review and Meta-analysis
Urinary tract infections (UTIs) are one of the most important infectious complications in kidney transplant recipients; hence, antibiotic prophylaxis is warranted. Due to limited information for selection of an appropriate antibiotic for prophylaxis, as well as the varying reports concerning…
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Artikel Jurnal
Evaluation of the Effect of Mechanical Ventilation on the Pharmacokinetic Parameters of Vancomycin in Intensive Care Patients: A Prospective Cohort Study
Objective: Intensive care unit (ICU) patients on mechanical ventilation, in particular, may experience changes in pharmacokinetics due to alterations in cardiac output and organ blood flow. This study aims to evaluate the effects of mechanical ventilation on the steady-state pharmacokinetic changes…
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Artikel Jurnal
Medication Use Patterns, Polypharmacy, and Potentially Inappropriate Medications among Institutionalized Older Adults in East Coast Malaysia: A Cross-sectional Study
Objective: Older adults need comprehensive healthcare with particular attention to medication management to prevent drug-related problems while ensuring optimal therapeutic outcomes. This study aims to assess the pattern of medication use, prevalence of polypharmacy, and the use of potentially…
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Artikel Jurnal
Anesthetic Approaches in Obese Patients: A Pilot Study Comparing the Impact of Desflurane versus Propofol on IL 6 Levels in Bariatric Surgery
Objective: Anesthetic and surgical stress may complicate the delicate immune state of obese patients. The immunomodulatory potential of anesthetics may play a role in minimizing complications. This study evaluates desflurane versus total intravenous anesthesia (TIVA) with propofol on surgical…
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Artikel Jurnal
Evaluation of the Benefits of a Pharmacist-led Educational Program on Achievement of Intra-ocular Pressure Target among Patients with Open Angle Glaucoma: A Qusai-experimental Study
Objectives: To evaluate the effectiveness of a pharmacist-led educational program in achieving intraocular pressure (IOP) target, as well as in improving adherence and proficiency in eye drop administration techniques among glaucoma patients. Methods: This qusai experimental study was conducted at…
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Artikel Jurnal
Impact of Delisting Non-Prescription Medicines from Health Insurance Coverage on Physicians’ Prescribing Behaviour in Iran: A Qualitative Study
Objective: In June 2018, Iran’s national health insurance policy excluded coverage for 79 nonprescription medicines (NPM) for outpatients aged over 12 years. Since physicians play a crucial role in healthcare delivery, this qualitative study explored how the delisting of NPM influenced their…
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Artikel Jurnal
Nirmatrelvir/Ritonavir Efficacy in Immunocompetent Patients with Confirmed Omicron Variant of Severe Acute Respiratory Syndrome Coronavirus 2: An Updated Systematic Review and Meta-analysis
The high mutations of the Omicron variant of severe acute respiratory syndrome coronavirus 2 raised concerns regarding the efficacy of antivirals. This meta-analysis aimed to determine the impact of nirmatrelvir/ritonavir on the outcomes of immunocompetent patients with confirmed Omicron variant…
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Artikel Jurnal
Assessment of Psychometric Properties of the Persian Version of the Medication Literacy Measure
Objective: Given the association between medication literacy (ML) and its correct use, assessing the status of ML is essential in the community. This study aimed to validate a Persian-language ML assessment instrument, addressing the lack of a previously validated Persian tool. Methods: This was a…
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Artikel Jurnal
Effectiveness of a Structured Pharmacist-led Intervention in Improving Pediatric Outpatient Prescribing Quality in a Resource-limited Setting: A Pre–post Study
Objective: The objective is to determine the prevalence and types of drug-related problems (DRPs), identify associated factors, and evaluate the impact of a structured pharmacist-led intervention on prescribing quality in pediatric outpatient care in a resource-limited health system with limited…
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Artikel Jurnal
Clinical and Demographic Characteristics in Schizophrenia Patients with and without a History of Taking Long-acting Injectable Antipsychotics: A Comparative Cross-sectional Study
Objective: Poor adherence to oral antipsychotics is an important challenge in schizophrenia, highlighting long-acting injectables (LAIs) as an alternative. This study aimed to compare the clinical and demographic profiles of patients with schizophrenia with prior LAI exposure versus those…