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The Journal of Association of Chest Physicians
ISSN 2320-8775 · Wolters Kluwer Medknow Publications · 311 articles in the index
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Journal Article
Heterogeneous Phenotypes and Treatment Responses in Pulmonary Alveolar Proteinosis
Pulmonary alveolar proteinosis (PAP) is a rare lung disease, and this case series describes three patients with heterogeneous clinical presentations, management strategies, and outcomes. Whole lung lavage is indicated for symptomatic patients with significant functional and gas exchange impairment…
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Journal Article
Pulmonary Hypertension and Malnutrition in Chronic Obstructive Pulmonary Disease: A Cross-sectional Study
Introduction: Chronic obstructive pulmonary disease (COPD) is associated with significant morbidity and increases the risk of complications such as pulmonary hypertension (PH). Most COPD patients also have malnutrition. Considering the substantial burden of COPD in India, we conducted this study to…
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Journal Article
Polyurethane-induced hypersensitivity pneumonitis: A preventable pulmonary hazard
Hypersensitivity pneumonitis (HP) is an immune-mediated interstitial lung disease caused by inhalation of various environmental and occupational antigens. Occupational exposure to polyurethane is an under-recognized cause, particularly in developing countries. We report a 40-year-old non-smoker…
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Journal Article
Evolving Trends in Asthma Exacerbations Among US Adults: Disparities by Age, Race, Socioeconomic Status, and Social Determinants of Health (2019–2024 NCHS Analysis)
Background: Asthma continues to impose a substantial chronic respiratory burden on the U.S. adult population, with outcomes shaped by a complex interplay of socioeconomic, demographic, and healthcare access factors. Objective: Characterizing how patterns of asthma exacerbation have shifted over…
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Journal Article
Evaluating the Diagnostic Yield of Bronchoalveolar Lavage in Suspected Sputum-Negative Pulmonary Tuberculosis
Background: Diagnosing sputum-negative pulmonary tuberculosis (PTB) remains challenging due to low bacillary load and absence of microbiological confirmation. This study evaluated the diagnostic yield of bronchoalveolar lavage (BAL) using Cartridge-Based Nucleic Acid Amplification Test (CBNAAT) and…
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Journal Article
The Sleep Score Showdown: Mallampati, STOP-BANG, Epworth Sleepiness Scale Versus the Apnea–Hypopnea Index Standard in Assessing the Severity of Obstructive Sleep Apnea
Context: Obstructive sleep apnea (OSA) poses significant health risks, with the Apnea–Hypopnea Index (AHI) from polysomnography serving as the diagnostic gold standard. Due to limited access, screening tools such as the Mallampati classification, STOP-BANG questionnaire, and Epworth Sleepiness…
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Journal Article
Digital Health Technologies in Pulmonary Disease Prevention: Applications and Implementation Strategies
Respiratory diseases impose a substantial global health burden, with preventive pulmonology strategies offering critical opportunities to reduce morbidity and mortality through early detection, risk factor modification, and disease progression prevention. Digital health technologies enable a…
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Journal Article
Optimizing Care in Pulmonary Hypertension Associated with Lung Disease: Evidence-Based Strategies and Emerging Therapies
Pulmonary hypertension (PH) related to chronic lung disease (group 3 PH) frequently complicates conditions such as chronic obstructive pulmonary disease (COPD) and interstitial lung diseases. Outcomes worsen considerably once pulmonary pressures become severe, yet therapeutic options remain…
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Journal Article
Tuberculosis and Isoniazid Acetylation: What A Clinician Needs to Know
Isoniazid (INH) acetylating status and its variability among different regions and parts of the world are well known; however, they are never elaborated much in day-to-day tuberculosis (TB) guidelines. Hence, we discuss three cases of pulmonary TB presenting with drug-induced hepatitis. Workup and…
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Journal Article
Rifampicin-induced Secondary Hyperparathyroidism in a Case of Isoniazid Monoresistant Pulmonary Tuberculosis
Antitubercular drug (ATD)-induced hypovitaminosis D3 and secondary hyperparathyroidism are less reported phenomena compared to other antitubercular therapy–induced adverse events. Rifampicin and isoniazid are often identified as the culprits in causing secondary hyperparathyroidism. The mechanism…
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Journal Article
To Study the Diagnostic Yield of Medical Rigid Thoracoscopy in Patients with Pleural Effusion of Unknown Etiology: A Cross-sectional Study
Introduction: Pleural effusion is a frequent presentation in pulmonary medicine, with 25% to 40% of exudative effusions remaining undiagnosed despite pleural fluid cytology and closed biopsy. Medical thoracoscopy (MT) enables direct pleural visualization and targeted biopsy under local anesthesia…
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Journal Article
Impact of Bacteriology on Outcome of Infective Exacerbation of Chronic Obstructive Pulmonary Disease in a Tertiary Care Hospital of Eastern India
Introduction Respiratory tract infection is a common precipitating factor of acute exacerbation of chronic obstructive pulmonary disease (AE-COPD). Early diagnosis and prompt treatment, with knowledge of the local bacteriological profile and antibiogram, are likely to reduce the case fatality rate…
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Journal Article
Bacteriological Profile and Antimicrobial Resistance Patterns in Ventilator-Associated Pneumonia: A Prospective Study from a Tertiary Care Center in Eastern India
Background: Ventilator-associated pneumonia (VAP) is a major cause of morbidity and mortality in critically ill patients requiring mechanical ventilation. The increasing burden of multidrug-resistant (MDR) organisms has complicated treatment and outcomes. This study aimed to determine the…
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Journal Article
Assessment of rapid bedside point of care diagnostic utility of cartridge-based nucleic acid amplification test (CBNAAT) in the diagno
Background: Extrapulmonary tuberculosis poses a great challenge in the diagnosis and management due to the paucibacillary nature of the disease and limited tests available for early diagnosis. Tuberculous lymphadenopathy is the most common extrapulmonary manifestation of tuberculosis (TB). The…
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Journal Article
Correct Use of Pressurized Metered-Dose Inhalers and Its Predictors among Patients Attending a Respiratory Medicine Outpatient Department in Eastern India
Background: Incorrect use of pressurized metered-dose inhalers (MDIs) compromises drug delivery in asthma and chronic obstructive pulmonary disease (COPD) management, with global error rates up to 94%. This cross-sectional study evaluated MDI technique correctness and predictors among patients in a…
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Journal Article
Linezolid-Induced Lactic Acidosis in Tuberculosis: A Systematic Review of Published Case Reports and Case Series
Linezolid is widely used in the treatment of drug-resistant tuberculosis (TB), despite being associated with severe adverse effects, including lactic acidosis, which remains underreported in the literature and is fatal in many cases. This systematic review followed Preferred Reporting Items for…
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Journal Article
Lung Oscillometry in Interstitial Lung Disease: Current Evidence and Clinical Application
Lung oscillometry test (LOT) is an emerging, noninvasive tool that assesses airway resistance and reactance during tidal breathing. Unlike spirometry, which depends on patient effort, LOT provides objective insights into small airway function and has shown potential utility in conditions where…
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Journal Article
Bridging Innovation and Access: Advancing Allergen Immunotherapy (AIT) in India
Background: In recent years, we have seen allergen immunotherapy (AIT) gain recognition as a disease-modifying option in allergic asthma. However, its use in day-to-day care remains limited due to concerns about safety, variable diagnostic standards, availability of allergen extracts, and trained…