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Journal of Investigative Medicine High Impact Case Reports
Scopus
ISSN 2324-7096 · SAGE Publishing · 1.497 artikel di indeks
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Artikel Jurnal
Successful Implementation of Peripheral Venoarterial ECMO in a Patient With Eisenmenger Syndrome as a Bridge to Lung Transplant: A Case Report
Eisenmenger syndrome (ES) is a form of cyanotic congenital heart disease resulting in pulmonary hypertension and right-to-left shunting. End-stage ES often requires lung transplantation and patients may require extracorporeal membrane oxygenation (ECMO) as a bridge, though the optimal cannulation…
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Artikel Jurnal
Myocarditis with Reversible Left Ventricular Dysfunction in a Patient Receiving Adalimumab: A Case Report
Legionella pneumophila is a well-recognized cause of community-acquired pneumonia, but its capacity to cause extrapulmonary complications, including myocarditis, remains underappreciated. Myocarditis is among the rarest and most serious cardiac manifestations of Legionella infection and may be…
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A Hidden Driver Mutation in Myeloproliferative Neoplasms: SH2B3 and Diagnostic Implications and Response to Ropeginterferon Alfa-2b
Myeloproliferative neoplasms (MPNs) are commonly linked to driver mutations in the JAK2, MPL, and CALR genes. In contrast, SH2B3 (LNK) mutations are uncommon and remain an under-characterized contributor to dysregulated JAK-STAT signaling. The clinical features and treatment responsiveness of…
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Artikel Jurnal
When Chest Pain Unmasks the Liver: Acute Pericarditis Leading to the Diagnosis of AIH–PBC Overlap Syndrome
Autoimmune pericarditis is commonly idiopathic but may represent the initial manifestation of systemic autoimmune disease. Hepatic autoimmune disorders rarely present with primary cardiac involvement, and recognition of extrahepatic presentations is essential for early diagnosis and prevention of…
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Artikel Jurnal
Diagnostic Uncertainty in Pancreatic Masses: The Critical Role of excluding Malignancy in Suspected Autoimmune Pancreatitis
Autoimmune pancreatitis (AIP) is an uncommon inflammatory condition of the pancreas characterized by glandular enlargement and ductal narrowing arising from dysregulated immune activity. Its clinical and imaging overlap with pancreatic malignancy makes accurate distinction essential. We describe a…
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Azathioprine-Induced Pancreatitis in a Patient With Autoimmune Hepatitis: A Case Report
A 67-year-old woman with biopsy-proven autoimmune hepatitis (AIH) developed acute pancreatitis shortly after starting azathioprine (AZA) and budesonide. She presented with abdominal pain, fever, and elevated lipase levels. Imaging confirmed acute interstitial edematous pancreatitis, and common…
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Pregnancy-Associated Cerebral Venous Thrombosis Presenting in the First Trimester: A Case Report
Cerebral venous thrombosis in pregnancy in the first trimester is a very rare condition but should not be confused with the clinical presentation of other common conditions in pregnancy such as pre-eclampsia. Although it is rare and difficult to diagnose, it is potentially serious and can increase…
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Survival After Catastrophic Antiphospholipid Syndrome With Diffuse Alveolar Hemorrhage
Antiphospholipid syndrome is a systemic autoimmune disorder characterized by thrombotic events in the presence of antiphospholipid antibodies including lupus anticoagulant, anticardiolipin, and anti-β2-glycoprotein I antibodies. Catastrophic antiphospholipid syndrome is a rare but life-threatening…
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Subacute Coronary Stent Thrombosis as the Initial Presentation of Acute Myeloid Leukemia: A Case Report and Literature Review
Subacute stent thrombosis is an uncommon but life-threatening complication of percutaneous coronary intervention (PCI). While mechanical and antiplatelet-related factors are most frequently implicated, systemic hypercoagulable conditions are increasingly recognized as important contributors. Acute…
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Artikel Jurnal
Pericardial Decompression Syndrome after Drainage of Malignant Pericardial Effusion: A Case Report
Pericardial decompression syndrome (PDS) is an uncommon but potentially fatal complication that can follow technically successful drainage of a hemodynamically significant pericardial effusion. A 61-year-old woman with stage IVB lung adenocarcinoma presented with progressive dyspnea and edema…
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Artikel Jurnal
Concomitant Left Ventricular and Popliteal Thrombectomy With Coronary Artery Bypass Grafting
Left ventricular (LV) thrombus in patients with severe coronary artery disease (CAD) poses a difficult decision regarding the safety and timing of revascularization. We report a 61-year-old woman presenting with non-traumatic right ankle pain, a consequence of popliteal artery cardioembolism…
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Misleading Capnography in Acute Pulmonary Embolism: Case Series of Masked End-Tidal CO Response During Airway Management
End-tidal carbon dioxide (ETCO 2 ) monitoring is the standard method for confirming endotracheal tube placement during emergency airway management. However, massive pulmonary embolism can create paradoxical capnography findings that complicate airway confirmation and resuscitation efforts. We…
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Artikel Jurnal
Isolated Ocular Relapse Following Prolonged Remission in Primary Central Nervous System Lymphoma: A Case Report
Primary central nervous system lymphoma (PCNSL) is a rare extranodal lymphoma most commonly involving the brain and leptomeninges. While high-dose methotrexate (HD-MTX)–based therapy has improved outcomes, relapse remains common and typically occurs within the CNS. Isolated ocular relapse after…
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Artikel Jurnal
Malignancy in Disguise: Transudative Malignant Pleural Effusion from Early-Onset Lung Adenocarcinoma
Malignant pleural effusions (MPEs) are almost always exudative, with only an estimated 3–4% meeting biochemical criteria for a transudate. Light’s criteria remain the standard method for classifying pleural effusions, and transudative effusions typically do not undergo cytologic evaluation. This…
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Artikel Jurnal
Encephalopathy Post CAR-T Cell Therapy in Relapsed/Refractory Multiple Myeloma: Beyond ICANS
Human herpesvirus 6 (HHV-6) reactivation is a rare but serious complication of chimeric antigen receptor T-cell (CAR-T) therapy that can overlap with immune effector cell-associated neurotoxicity syndrome (ICANS) or cytokine release syndrome (CRS), making diagnosis and management challenging. We…
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Artikel Jurnal
Choreiform Movements and Pachymeningeal Enhancement in an Elderly Patient With Abnormal Blood Counts: A Case Report and Review of Literature
Polycythemia vera (PV) is a clonal myeloproliferative neoplasm primarily caused by the JAK2V617F mutation, present in 95% of patients. It results in erythropoietin-independent hematopoietic proliferation, erythrocytosis, increased hematocrit (Hct), leukocytosis, thrombocytosis, and hyperviscosity…
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Artikel Jurnal
Acute Colonic Pseudo-obstruction Following Massive Bupropion Overdose
Bupropion is an atypical antidepressant that inhibits norepinephrine and dopamine reuptake. Poison control data demonstrate toxic effects at doses as low as 600 mg. Common adverse effects of overdose include tachycardia, seizures, and cardiac arrhythmias. Gastrointestinal complications are rarely…
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Artikel Jurnal
Occult Breast Carcinoma Presenting with Extensive Bone Involvement in the Absence of an Identifiable Primary Breast Lesion: A Case Report
Occult breast cancer (OBC) is a rare and diagnostically challenging subtype of breast carcinoma characterized by axillary or distant metastases without an identifiable primary breast lesion. We report an unusual presentation of OBC in a patient with diffuse osteolytic bone metastases and axillary…
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