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Journal of Cardio-Thoracic Medicine
ISSN 2345-2447 · Mashhad University of Medical Sciences · 421 articles in the index
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Immunomodulatory Therapies in Hypersensitivity Pneumonitis: A Comprehensive Review
Hypersensitivity pneumonitis (HP) is an immune-mediated interstitial lung disease (ILD) caused by repeated inhalation of environmental antigens. Clinically, it varies widely from temporary, reversible inflammation to long-term, progressive fibrosis. The primary approach in managing HP remains…
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Pulmonary Complications and Systemic Abnormalities in Post-COVID-19 Patients: A 3-Month
Introduction: The coronavirus disease 2019(COVID-19) pandemic has had significant acute and long-term health impacts. Persistent pulmonary and systemic complications after recovery remain inadequately studied. This cohort study aimed to assess chronic respiratory and systemic abnormalities in…
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Outcome of Fresh Frozen Plasma Versus Albumin in Priming Solution of Extracorporeal Circuit in Neonatal Cardiac Surgery: A Prospective Comparative Observational Study
Introduction: In neonatal cardiac surgery, the choice of cardiopulmonary bypass (CPB) priming fluid is crucial. Fresh frozen plasma (FFP) provides essential coagulation factors that can help reduce bleeding, while albumin helps maintain oncotic pressure and may protect renal function. This study…
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VKORC1 and CYP2C9 Genetic Variants Coumarin Response in the Mestizo-Mexican Population
Introduction: Polymorphisms in the genetic variations of vitamin K epoxide reductase complex subunit 1 (VKORC1) and Cytochrome P450 subfamily IIC polypeptide 9 (CYP2C9) have been shown to cause variability in anticoagulant response across various ethnic groups. In the Mestizo-Mexican population…
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Utility of Forced Oscillation Technique in Detecting Obstruction in Asthma and the Significance of ‘Isolated Increase in R5-R20’ (II R5-R20)
Introduction & objective : The objective of this retrospective observational study was to investigate the role of forced oscillometry in detecting airway obstruction in asthma and to compare its sensitivity to that of spirometry in detecting airway obstruction.Method: The retrospective…
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A Game Changer for Low and Middle Income Countries: Del Nido Cardioplegia for Adult Cardiac Surgery – A Tertiary Care Experience
Introduction: Del Nido Cardioplegia (DNC) offers prolonged myocardial protection through a single-dose approach.Methods: This retrospective study involved 175 adult patients from five surgical groups (DVR, MIS‑MVR, MVR via sternotomy, AVR, congenital repairs). Statistical analysis was conducted…
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Coronary Artery Bypass Grafting by Total Arterial Revascularization in a Patient with Elephantiasis
Elephantiasis, characterized by chronic lymphatic obstruction and massive limb swelling, poses significant challenges in surgical management due to altered anatomy, difficulty in vein harvesting, impaired wound healing, and an increased risk of infection and fluid imbalance. These complications…
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Role of Near Infrared Spectroscopy Monitoring in Intra-Operative Period for Neurological Outcomes in Complex Aortic Surgeries- A study of 50 Adult Cases
Introduction: Complex aortic surgeries are associated with a considerable risk of perioperative neurological complications, mainly due to cerebral hypoperfusion, ischemia, or embolic events. Early recognition of cerebral oxygen imbalance during surgery may help in reducing postoperative…
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Diabetes, Hypertension, Obesity, and Age as Predictors of Severe COVID-19: A Mathematical Modeling Study
Objective: To analyze an epidemiological model of coronavirus disease 2019 (COVID-19) transmission and identify patient characteristics associated with disease severity.Materials and Methods: An extended SIR-based compartmental model was developed, incorporating asymptomatic/symptomatic…
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Perioperative Predictors of Acute Kidney Injury in Off-pump Coronary Artery Bypass Grafting Surgery
Introduction: Acute kidney injury (AKI) after cardiac surgery is associated with increased morbidity and mortality. Risk factors for AKI during off-pump coronary artery bypass grafting (OPCAB) are poorly understood. Our aim in this study is to identify the relationship between perioperative…
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Retrospective Analysis of Single-Incision Right Mini-Thoracotomy for Mitral Valve Replacement: A Cost-Effective Minimally Invasive Strategy from a High-Volume Center in Western India
Introduction: Minimally invasive cardiac surgery (MICS) has redefined mitral valve replacement (MVR), but its adoption in low- and middle-income countries (LMICs) is limited by resource constraints and cost-effectiveness concerns. This study evaluates single-incision right mini-thoracotomy with…
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Reported Satisfaction with Health and Medical Services among Mashhad Pilgrims at the End of the Safar Lunar Month
Introduction: We aimed to evaluate the pilgrims’ satisfaction with the health, medical, and pharmaceutical services in Mashhad at the end of Safar.Methods: This was a cross-sectional study conducted in the Safar Lunar Month. Pilgrims were recruited using a convenience sampling method of individuals…
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Coronary-Cameral Fistula from RCA to RA Masquerading as RSOV: A Case Report
Introduction: Coronary-cameral fistulas (CCFs) are rare congenital anomalies characterized by abnormal communications between a coronary artery and a cardiac chamber. These fistulas can pose significant diagnostic challenges when they mimic other cardiac pathologies such as ruptured sinus of…
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ChatGPT: AI-Driven Patient Education on Pacemaker Monitoring and Recent Trends in Upcoming Treatments, Along with Future Innovations
OpenAI, a leading artificial intelligence research organisation based in California, is committed to developing technologies that align with human values and safety. Its latest flagship model, ChatGPT-4o, represents a significant advancement in natural language processing, featuring multimodal…
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Utility of Serum Urea-to-Albumin Ratio in Predicting Length of Stay in Patients with Myocardial Infarction: A Retrospective Cohort Study
Introduction: This study aimed to assess the effectiveness of the Serum Urea-to-Albumin Ratio (UAR) as a predictor of prolonged Length of Stay (LOS) in patients admitted with Myocardial Infarction (MI).Materials and Methods: This retrospective study analyzed data from 195 patients admitted with MI…
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Knowledge, Attitudes, and Practices Regarding Sleep-Related Breathing Disorders: A Cross-Sectional Study among Medical Students
Introduction: Sleep-related breathing disorders (SRBD) affect millions globally and are associated with serious health complications such as cardiovascular diseases, stroke, and impaired cognitive function. Early recognition and management are crucial in reducing the burden. However, knowledge…
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Acute Kidney Injury after Coronary Artery Bypass Grafting in Diabetic and Non-Diabetic Patients
Introduction: In recent years, there has been a lack of reliable studies comparing the incidence of acute renal failure after coronary artery bypass grafting (CABG) in patients with and without diabetes. The present study aims to compare the frequency of acute kidney injury (AKI) in diabetic…
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The Potential Role of MicroRNAs in Cardiac Myxoma: A comprehensive Review on the Current Evidence
Cardiac myxoma (CM) is the most common primary cardiac tumor, often benign but potentially life-threatening due to embolic events and intra-cardiac obstruction. Recent advances suggest a significant role for microRNAs (miRNAs) in CM pathogenesis, diagnosis, and treatment. This review aims to…
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Weight No Barrier: Anaortic Off-Pump Total Arterial CABG in a 107-kg Patient
Total arterial, anaortic off-pump coronary artery bypass grafting (OPCABG) is a refined surgical approach that minimizes the risks of cardiopulmonary bypass and aortic manipulation. This case report describes a 44-year-old male with triple vessel coronary artery disease who underwent successful…
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The Comparison of Hematological Factors between Employees of S.G.P.C Gas Company and a General Population of Employees
Introduction: The aim of our study was to compare complete blood count (CBC) parameters between two populations to determine if there is a need for intervention to improve the health status of workers in the work place.Methods: This study utilized a comparative cross-sectional studydesign. A total…