367 hasil
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Journal of Nephropharmacology
Scopus
ISSN 2345-4202 · Society of Diabetic Nephropathy Prevention · 367 artikel di indeks
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Artikel Jurnal Teks lengkap
AI-driven innovations in intensive care nephrology; bridging intensive care and kidney diseases
This narrative review explores the transformative role of artificial intelligence (AI) in critical care nephrology, focusing on the early detection, risk prediction, and management of acute kidney injury (AKI) and the optimization of renal replacement therapies in intensive care settings. Drawing…
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Placenta, platelets, and podocytes; the triad of renal injury in pregnant women with antiphospholipid syndrome
The intricate triad of placenta, platelets, and podocytes represents a central framework for understanding the multifactorial renal injury associated with antiphospholipid syndrome (APS) during pregnancy. This triadic interaction underscores a pathophysiological continuum driven by thrombosis…
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Effect of hemodiafiltration versus high flux hemodialysis on reduction ratio of adiponectin and complement factor D as markers of dialysis adequacy
Introduction: Dialysis therapy has significantly advanced due to innovations in dialyzer technology and hemodialysis (HD) techniques, leading to improved patient quality of life. The effectiveness of dialysis treatment can be assessed by evaluating the reduction ratio (RR) of…
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Association between anti-erythropoietin antibody levels and treatment response in hemodialysis patients with end-stage renal disease: A cross-sectional study from Iraq
Introduction: The therapeutic efficacy of erythropoietin (EPO) may be diminished by the formation of anti-erythropoietin antibodies (AEAs), potentially resulting in therapy failure. Objectives: This retrospective study included 84 hemodialysis patients with end-stage renal disease (ESRD) treated…
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Potential of a palladium–Mexidol complex in normalization of liver tests as a dual organoprotective of hepato-renal function in a paracetamol-induced rat model
Introduction: Paracetamol overdose is a primary cause of acute liver and renal damage due to oxidative stress and depletion of glutathione reserves. Palladium-Mexidol complexes have demonstrated significant antioxidant, membrane-protective, and cytoprotective properties. Objectives: This study…
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Investigation of CTLA-4 gene polymorphisms in a sample of Iraqi children with newly diagnosed type 1 diabetes mellitus
Introduction: Type 1 diabetes mellitus (T1DM) is a complicated autoimmune disorder that is marked by the destruction of pancreatic islands by T cells. It is widely believed that genetic factors play a crucial role in the development of T1DM and other autoimmune diseases. At present, the…
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Economic trend in kidney transplantation costs in the world; insights from the ISN global kidney health atlas 2019-2023
Introduction: Kidney transplantation is a critical treatment for end-stage kidney disease, but its costs vary widely across countries and over time. Objectives: This study investigates changes in kidney transplantation costs between 2019 and 2023 using data from the International Society of…
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Chronic kidney disease and right ventricular dysfunction; an echocardiographic assessment in hemodialysis patients
Introduction: Cardiovascular complications are the primary cause of mortality in individuals with advanced kidney disease, with heart failure being the most prevalent condition. Right ventricular (RV) dysfunction plays a critical role in increasing morbidity and mortality rates in patients with…
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The role of intestinal microbiota in the pathogenesis of nephropathy in patients with metabolic syndrome; a systematic review
Introduction: The gut microbiota plays a vital role in maintaining metabolic and renal health. Dysbiosis associated with metabolic syndrome contributes to the development of nephropathy through mechanisms involving inflammation and the production of uremic toxins. Objectives: This study aims to…
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Administration of vadadustat for anemia of chronic kidney disease; an updated review
Chronic kidney disease (CKD) is a global health burden, often complicated by anemia due to impaired erythropoietin production and iron dysregulation. Vadadustat, an oral hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI), has emerged as a promising therapeutic option for managing…
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Relationship between left ventricular end-diastolic pressure and contrast-induced nephropathy; a systematic review and meta-analysis
Introduction: With the increased use of interventional therapies, the incidence of contrast-induced nephropathy (CIN) has also risen. However, the relationship between left ventricular end-diastolic pressure (LVEDP) levels and the risk of CIN remains unclear. Therefore, this study aimed to…
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Application of the updated international IgA nephropathy prediction tool in pediatric patients
The International IgA Nephropathy Prediction Tool (IgAN-PT) aims to provide individualized risk assessments for patients diagnosed with primary IgAN, which is a prevalent cause of kidney disease, especially among young adults. This tool helps clinicians to understand the risk for worsening kidney…
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Thrombotic microangiopathy in IgA nephropathy; new evidence and ideas
The Oxford classification for IgA nephropathy (IgAN) does not currently include thrombotic microangiopathy (TMA) as a parameter, despite evidence that TMA can occur in IgAN patients and impact outcomes. Prior studies have found that a significant proportion of IgAN patients have histological…
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Earthquake-related acute kidney shut down; an overview of pre-existing associated factors
Acute kidney injury (AKI) is a critical complication that can arise in the aftermath of earthquakes, particularly due to crush syndrome, which is the second most frequent cause of mortality in such disasters. The causes of AKI in earthquake victims are multifactorial, including direct renal trauma…
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Protective effects of bexagliflozin on renal function in a rat model of ischemia-reperfusion injury; an experimental animal study
Introduction: Ischemia-reperfusion injury (IRI) is a significant clinical challenge that often leads to acute kidney injury (AKI), adversely affecting renal function and patient outcomes. Recent advancements in pharmacotherapy have highlighted the potential of sodium-glucose cotransporter-2 (SGLT2)…
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Air pollution and kidney disease; a comprehensive updated overview of recent evidence on functional and structural alterations
The association between air pollution and renal health has gained increasing attention in recent years, with evidence suggesting that prolonged exposure to air pollution poses significant threats to both renal function and structural integrity of kidneys, with both immediate and long-term…
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Complications of remdesivir in COVID-19 patients with kidney disease: a retrospective cohort study
Introduction: The COVID-19 pandemic has highlighted the vulnerability of patients with chronic kidney disease (CKD) to severe complications from the virus. Remdesivir, an antiviral drug initially developed for Ebola, has emerged as a treatment option for COVID-19, yet its safety and efficacy in…
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The association between triglyceride-glucose index and contrast-induced nephropathy; a systematic review and meta-analysis
Introduction: The triglyceride-glucose index (TyG) is an indicator of insulin resistance, which can cause chronic dysfunction in renal performance. Accordingly, the present study aimed to examine the association between high TyG index levels and the risk of contrast-induced nephropathy (CIN) using…
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Comparison the clinical efficacy of intravenous fentanyl and ketorolac in relieving renal colic pain; a controlled randomized clinical trial
Introduction: Renal colic pain is due to increased pressure on the wall of the urinary tract and is caused by the passage of a stone through the urinary tract. Although most kidney stones are eliminated spontaneously, rapid relief of the patient’s pain is an important issue in the acute phase…
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Immune checkpoint inhibitors and IgA nephropathy; A rare side effect
The pathophysiological mechanisms of secondary IgA nephropathy (IgAN) containing IgA-mediated immune complex deposition in the glomeruli. However, the specific triggers can vary widely, including infections, liver disease, and malignancies, in addition to drug-induced factors. IgAN is a rare…