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Current Medicine Research and Practice
ISSN 2352-0817 · Wolters Kluwer Medknow Publications · 504 artikel di indeks
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When cycles influence career and connections: How pre-menstrual symptoms affect the work and social life of young women in Pune
Background: Pre-menstrual symptoms (PMSs) are cyclic phenomena that affect a significant proportion of menstruating women. It comprises physical, emotional, and behavioural symptoms that occur during the luteal phase of the menstrual cycle. Despite its widespread occurrence, PMS remains…
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Health promotion strategies and quality of life among postmenopausal women: A systematic review of evidence from 2016–2024
Menopause, the permanent cessation of menstruation, marks a critical transition in women’s health. In India, menopause occurs earlier (mean age 46.2 years) than the global average of 51 years, increasing vulnerability to physical and psychological problems. Health promotion through lifestyle…
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Serious adverse event reporting in India: Bridging regulatory requirements and practical challenges
The primary objective of clinical trials is to determine the safety, efficacy and tolerance of the researches drug. One of the most frequent outcomes observed in clinical trials is severe adverse events (SAEs), which may occur during the research period or even after its completion. Due to the…
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Acute lymphoblastic leukaemia with renal and extranodal involvement mimicking lymphoma in an adolescent
Acute leukaemia is the most common paediatric malignancy, typically characterised by pallor, fever and haemorrhagic symptoms. However, aberrant extramedullary involvement may mask the diagnosis in certain cases. We report a 15-year-old male patient who presented with persistent fever, regional…
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Ultrasonographic measurement of optic nerve sheath diameter in tuberculous meningitis: Clinico-radiological correlations and outcome
Background: Raised intracranial pressure (ICP) is a major cause of neurological complications in tuberculous meningitis (TBM), contributing significantly to morbidity and mortality. Ultrasonographic measurement of the optic nerve sheath diameter (ONSD) is a rapid, bedside and non-invasive technique…
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The Landscape of Insights and Approaches: Surgeons and Residents Tackling Gallstone Spillage in Saudi Arabia
Background: Laparoscopic cholecystectomy (LC) is a widely adopted technique for treating symptomatic cholelithiasis. However, gallstone spillage during the procedure poses significant risks for post-operative complications. Aim: This study aimed to evaluate surgeons’ and residents’ knowledge…
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Spatial distribution of dengue serotype-specific cases in settings of Uttar Pradesh, India
Background: Dengue is an emerging vector-borne disease of high significance to public health. Severe forms of dengue fever, such as Dengue Haemorrhagic Fever and Dengue Shock Syndrome, may lead to fatal consequences in areas where more than one dengue serotype is present. Aim: The present study was…
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Isolated unilateral congenital knee dislocation in a neonate
Congenital dislocation of the knee (CDK) is a rare orthopaedic condition identified at birth, characterised by hyperextension and anterior displacement of the tibia relative to the femur. We present the case of a term neonate with a hyper-extended and anteriorly dislocated right knee, observed…
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Health-related quality of life in patients following gastrointestinal surgery and liver transplantation: A cross-sectional study from a tertiary care centre in India
Background: Health-related quality of life (HRQOL) is an important patient-reported outcome after gastrointestinal (GI) surgery and liver transplantation. Data from India, where patients present with diverse socioeconomic backgrounds and limited access to post-operative rehabilitation, are scarce…
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Incidence of cancer chemotherapy-induced thrombocytopenia and its treatment outcomes at an oncology centre
Background: Chemotherapy-induced thrombocytopenia (CIT) is a common haematological adverse effect in patients with cancer receiving cytotoxic chemotherapy. It is associated with an increased bleeding risk, treatment delays, dose reductions and compromised therapeutic outcomes. Despite global…
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Predominance of influenza A(H3N2) and Victoria lineage of influenza B in patients with influenza-like illness: A laboratory-based surveillance study from Rajasthan, India
Background: The relative prevalence of specific influenza subtypes and lineages significantly impacts seasonal epidemiology and the effectiveness of vaccines. Detailed virological data from regional centres in India are crucial, yet often limited. Aims: The objective is to determine the subtype and…
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Lignocaine versus dexmedetomidine infusion for post-operative pain relief in patients undergoing laparoscopic cholecystectomy: A randomised controlled study
Background and Aim: Opioid-sparing multi-modal analgesia is an important component of the enhanced recovery after surgery (ERAS) protocol. Lignocaine and dexmedetomidine have emerged as effective anaesthetic adjuvants. Laparoscopic cholecystectomy, an ambulatory surgery, has advantages such as…
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Rare coexistence of segmental jejunal dilatation, gastric heterotopia and malrotation in an infant with congenital heart disease: A diagnostic dilemma
Segmental jejunal dilatation (SJD) is an exceptionally rare congenital condition that is often misdiagnosed. When associated with gastric heterotopia and intestinal malrotation, it presents a unique diagnostic and therapeutic challenge to the surgeon. We report the case of a 5½ month-old female…
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The vicious cycle: Delirium, sedation, and patient outcomes in critical care
Background: Delirium is a prevalent neuropsychiatric complication in critically ill patients, associated with increased morbidity, mortality and long-term cognitive impairment. Sedation practices are increasingly recognised as modifiable risk factors for delirium; however, the optimal approach…