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Clinical Nutrition Experimental
ISSN 2352-9393 · Elsevier · 134 articles in the index
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Journal Article
Potential synergistic antioxidant effect of thymoquinone and vitamin E on cisplatin-induced acute nephropathy in rats
Summary: Background: Nephrotoxicity occurs as a side effect of treating solid tumor with a single dose of cisplatin as anticancer drug because of the increase in oxidative stress. In this study, the free radicals scavenging capacity of thymoquinone (TQ) and vitamin E were tested to decrease the…
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Journal Article
Practical guidance for the use of indirect calorimetry during COVID 19 pandemic
Summary: The daily practice requires the use of indirect calorimetry to define the energy requirements of intensive care patients. In the time of COVID-19 pandemic, this practice is challenging. The purpose of this methodology paper is to provide practical guidance to health professionals to…
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Journal Article
Food consumption patterns, physical activity and overweight and obesity among undergraduates of a private university in Nigeria
Summary: Background: Non Communicable Diseases which is strongly associated with overweight and obesity have overtaken communicable diseases as the leading causes of morbidity and mortality. The changing disease pattern has been attributed to nutrition transition and inadequate exercise. This study…
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Journal Article
Probiotics for infantile colic
Summary: Background: The prevalence of infant colic is high and it has a significant impact on the live of the infants and their families, given that effective treatment has not been found. Objective: The aim of this study to evaluate the effects of pedilact probiotic drops for the treatment of…
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Journal Article
Low level of phosphate in male patients reporting swallowing disturbances in early Parkinson's disease
Summary: Background & aim: Swallowing disturbances are associated with older age as well as with other subclinical disturbances of multifactorial origin in patients with Parkinson's disease (PD). This study assesses nutritional markers and whole-body impedance data to better understand swallowing…
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Journal Article
Gingerol supplementation does not change glucose tolerance, lipid profile and does not prevent weight gain in C57BL/6 mice fed a high-fat diet
Summary: We hypothesized that gingerol supplementation would exert protective effects against high-fat diet (HFD)-induced weight gain via regulation of lipid and glucose homeostasis. To test our hypothesis, forty C57BL/6 mice were fed a standard diet (SD), SD plus gingerol (SDG), high-fat diet…
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Journal Article
Nutritional assessment, handgrip strength and adductor pollicis muscle thickness in patients with chronic viral hepatitis
Summary: Backgrounds & aims: Nutritional status of patients with chronic liver disease has been gaining prominence since it is directly associated to morbidity and mortality. However, there is still no consensus on the best method for nutritional assessment given the great variability of body…
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Journal Article
Zinc status (intake and level) of healthy elderly individuals in Riyadh and its relationship to physical health and cognitive impairment
Summary: Objective: The aim of the current study was to assess the zinc status (intake and level) and its relationship to cognitive impairment among men and women aged 65 years and above in Riyadh, Saudi Arabia. Methods: A cross-sectional single-center study was conducted in 400 participants (200…
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Journal Article
Effect of oral l-Glutamine supplementation on Covid-19 treatment
Summary: Objectives: The aim of this study is to investigate the effect of oral l-Glutamine supplementation on hospitalization time, need for intensive care unit and Coronavirus Disease-19 (Covid-19) mortality. Methods: The study included 30 Covid-19 patients using l-Glutamine and 30 Covid-19…
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Journal Article
Chronic leucine supplementation does not prevent the obesity and metabolic abnormalities induced by monosodium glutamate
Summary: Leucine (Leu) is an essential branched amino acid that regulates several aspects of metabolism and may have the ability to mitigate obesity and type 2 diabetes. In the present study, we evaluated the effect of chronic Leu supplementation on the obesity and metabolic abnormalities induced…
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Journal Article
Perioperative nutrition in extremely preterm infants undergoing surgery for patent ductus arteriosus
Summary: Background and aims: Patent ductus arteriosus is a common neonatal morbidity affecting more than half of infants born extremely preterm. Suboptimal nutrition in extremely preterm infants in general has been demonstrated in recent studies. The aim of this study was to describe perioperative…
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Journal Article
The effect of a single mega dose injection of vitamin D on serum adiponectin concentration at first gestational diabetes mellitus: A randomized controlled clinical trial
Summary: Background & aims: Vitamin D is being increasingly recognized for its important non-skeletal functions including endocrine actions. This study investigated if a single, large, intramuscular postpartum injection of vitamin D improve adiponectin levels among women with gestational diabetes…
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Journal Article
Cnidoscolus aconitifolius leaf extract exhibits comparable ameliorative potentials with ascorbate in dimethylnitrosamine-induced bone marrow clastogenicity and hepatotoxicity
Summary: Cnidoscolus aconitifolius (CA) is an edible perennial shrub with promising medicinal properties. We therefore investigated the ameliorative potentials of CA (400 mg/kg) by comparing with ascorbate (400 mg/kg) in dimethylnitrosamine (DMN)-induced clastogenicity and hepatotoxicity…
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Journal Article
Calcium and phosphorus bioaccessibility from different amino acid-based medical nutrition formulas for infants and children under in vitro digestive conditions
Summary: Objective: Mineral bioavailability from food is important for infants and young children. Mineral bioavailability is influenced by many factors, including e.g., the food matrix, mineral composition, and route of administration. Moreover, physiological factors, such as mineral status and…
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Journal Article
Geographic regions with high prevalence of nonalcoholic steatohepatitis-related hepatic fibrosis are also observed to demonstrate high prevalence of metabolic disease risk factors and low consumption of fruits and vegetables
Summary: Background & aims: Nonalcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease globally. We aim to evaluate prevalence and predictors of hepatic fibrosis among NAFLD patients, focusing on metabolic co-morbidities and dietary patterns. Methods: Quest Diagnostics…
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Journal Article
The supplementation of pasak bumi (Eurycoma longifolia Jack.) in undernourished rats to increase spatial memory through antioxidant mechanism
Summary: Undernourished interferes with the synthesis of antioxidants enzymes, causing oxidative stress in the brain. They will damage the cellular components of the brain and result in decreased intelligence. Pasak bumi (Eurycoma longifolia. Jack) is an endemic plant in Kalimantan that has…
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Journal Article
Biochemical changes associated with low and very low calorie diets on lipid metabolism, iron profile and kidney function in obese rats
Summary: Obesity is the most prevalent nutritional disorder. Healthy diets helps people maintain and improve their general health. This study aimed to assessment of low and very low calorie diets through determination of its effect on lipid metabolism, iron profile and kidney function in obese male…
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Journal Article
Ultrasound method of the USVALID study to measure subcutaneous adipose tissue and muscle thickness on the thigh and upper arm: An illustrated step-by-step guide
Summary: Objective: So far there is no standardised widely accepted ultrasound method for assessment of both subcutaneous adipose tissue and muscle mass in healthy subjects, patients and ICU patients. The goal is to provide an illustrated step-by-step guide of the ultrasound method developed since…
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Journal Article
Possible ameliorative role of green tea on chronic alcohol mediated renal toxicity of STZ -induced diabetic rats
Summary: This research was planned to assess the protective effect of aqueous green tea extract (AGTE) in alcohol treated diabetic rats. This study was examined, whether 20% v/v of 5 g/kg.b.w alcohol intake exacerbates diabetes-induced renal damage associated with an escalated nitroxidative stress…
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Journal Article
An in vitro explant model for studies of intestinal amino acid metabolism
Summary: Background & aims: The main role of the small intestine to absorb the bulk of dietary nutrients, including proteins and amino acids (AA). Enterocytes have long been considered a major player in amino acid homeostasis, especially the glutamine–citrulline–arginine crossroads. In vivo…