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npj Science of Food
Scopus
ISSN 2396-8370 · Nature Portfolio · 853 articles in the index
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Journal Article
Application of HepG2-derived organoid and organ-on-a-chip platforms in elucidating selenium-mediated protection against cadmium-induced liver dysfunction
Abstract HepG2 cells were cultured into liver organoids (more native liver-like than 2D cultures) and integrated into a microfluidic chip, which regulates flow, nutrients, and waste to simulate in vivo hepatic microcirculation. Key findings: Cadmium (Cd) exposure shows a positive dose-response with…
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Journal Article
Integrated metabolomics and metagenomics uncover pathogenic mechanisms of Fusarium wilt and faba bean defense responses
Abstract Fusarium wilt diseases pose a huge threat to faba bean (Vicia faba L.) production globally, with significant outbreaks in Chongqing, China. Symptomatic plants showed wilting leaves and rotten roots, ultimately perishing in the advanced stage. Morphological features, multilocus phylogenetic…
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Journal Article
Listeria monocytogenes detection assay via aptamer-functionalized magnetic bead enrichment coupled with RPA-CRISPR/Cas12a lateral flow strips
Abstract Conventional detection methods for Listeria monocytogenes suffer from limitations including lengthy procedures, equipment dependency, and operational complexity, making them unsuitable for rapid on-site detection. Therefore, this study developed an LM-RPA-Cas12a-LFA detection method…
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Journal Article
Plasmidomic landscape of Staphylococcus aureus and the emergence of a CC5 subclade harboring the conjugative plasmid pSK41: implications for food safety and antimicrobial resistance
Abstract Staphylococcus aureus can contaminate food products and persist in food-related environments, posing significant challenges to food safety and public health. However, the role of plasmids in mediating antimicrobial resistance (AMR) and facilitating host adaptation in S. aureus has been…
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Journal Article
From rosemary and coffee to bioactive nanovesicles: exploring new frontiers in food functional ingredients
Abstract Plant-derived vesicles (PDVs) are lipid-membrane structures that enclose proteins, lipids, nucleic acids and metabolites, reflecting the phytochemical profile of their plant source. This study investigated PDVs from Rosmarinus officinalis leaves (RVs) and Coffea arabica powder (CVs)…
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Journal Article
Key sweet-aroma compounds and formation mechanisms in Mengding bud yellow tea using HS-SPME-GC-MS and sensomics
Abstract Mengding Bud Yellow Tea (MDBYT) is distinguished by its characteristic sweet and umami aroma. This study integrated quantitative descriptive analysis, HS-SPME-GC-MS, and UPLC-QQQ-MS to systematically elucidate, for the first time, the dynamic evolution of MDBYT aroma and its formation…
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Journal Article
A small molecule strategy with forskolin and p38 inhibitor for serum-free muscle stem cell expansion
Abstract Cultured meat represents a promising sustainable food source, yet the development of efficient serum-free media remains a key bottleneck. Small molecules offer a cost-effective approach to system optimization. Through a functional screening of proliferation activators in bovine muscle stem…
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Journal Article
Cheese consumption and lower cholelithiasis risk a prospective UK biobank study with HDL-C mediation
Abstract Cholelithiasis affects 10–20% of adults globally, and while cheese consumption may influence risk, underlying biological pathways remain unclear. In this prospective cohort study of 399,467 UK Biobank participants without prior cholelithiasis, we examined cheese intake frequency (never to…
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Journal Article
Towards real-time pork breed and boar taint classification using rapid evaporative ionisation mass spectrometry
Abstract To help counteract food fraud and meet consumer expectations, the pork industry requires reliable quality-monitoring and traceability systems. In this context, rapid evaporative ionisation mass spectrometry (REIMS) could be rolled out as a real-time, accurate metabolic fingerprint-based…
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Journal Article
Milk proteins and fat influence Ag migration from model dairy packaging containing silver nanoparticles
Abstract We investigated migration of Ag from model Ag nanoparticle (AgNP)-loaded polyethylene films into bovine milks with varying milkfat content after storage for 10 days at 20 °C. Ag migration into 2% fat milk (2.18 ± 0.03 ng/cm2) was comparable to that observed in skim milk (2.16 ± 0.14…
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Journal Article
No indication of histological changes in embryonic somatosensory cortex development upon maternal aspartame consumption in mice
Abstract Non-nutritive sweeteners are widely used in multiple diets and are considered a healthy alternative for pregnant women reducing sugar consumption, thereby preventing maternal obesity and gestational diabetes. While some controversies have been raised regarding their safety for human…
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Journal Article
Lactobacillus paracasei fermentation enhances the aroma profile and antidiabetic efficacy of goji berry juice
Abstract Goji berry (Lycium barbarum L.) is rich in bioactive compounds, and its functional efficacy can be further enhanced through fermentation. This study evaluated the impact of Lactobacillus paracasei-fermentation on the quality attributes of goji berry juice and its in vivo antihyperglycemic…
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Journal Article
Distinct Limosilactobacillus reuteri microcapsule models: construction and therapeutic evaluation in DSS-induced colitis mice
Abstract The limited stability of L. reuteri in liquid formulations during storage, transport, and gastrointestinal transit presents a major challenge for its application as a probiotic. To address this, our study developed two distinct microcapsulation models for L. reuteri A-1, tailored for…
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Journal Article
A novel LC-MS/MS multi-group method for simultaneous determination of antimicrobial residues in legume-based alternative proteins
Abstract A novel liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed and validated for the simultaneous analysis of three different classes of veterinary drugs—antibiotics, antifungals, and antiparasitics—in legume-based alternative protein samples, e.g. beans, peas, and…
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Journal Article
Distinct transmission routes of Salmonella enterica serovars during pig growth on farms
Abstract Non-typhoidal Salmonella enterica is a major foodborne pathogen, with pigs and pig-derived products serving as key transmission sources of human infection. In this study, we applied whole-genome sequencing (WGS) to investigate the prevalence, transmission dynamics and antimicrobial…
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Journal Article
Machine learning elucidates associations between oral microbiota and the decline of sweet taste perception during aging
Abstract Aging-induced deterioration in taste perception can result in loss of appetite and malnutrition in the elderly, posing a substantial challenge to healthy aging. In oral cavity, the oral microbiota, food particles, and taste receptors interact extensively under the flow of saliva. Although…
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Journal Article
A unified knowledge graph linking foodomics to chemical-disease networks and flavor profiles
Abstract Modern nutrition science still lacks a comprehensive, machine-readable map linking diet to molecular composition and biological effects. Here we present FoodAtlas, a large-scale knowledge graph that links 1430 foods to 3610 chemicals, 2181 diseases, and 958 flavor descriptors through…
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Journal Article
Incidental food nanoparticles from freshwater clam soup stabilize Pickering emulsions
Abstract Daily foods contain abundant amounts of nanoparticles produced by the self-assembly of amphiphilic food components during processing. These nanoparticles are referred to as incidental food nanoparticles (iFNPs) because they are formed incidentally rather than through a specific…
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Journal Article
Optimizing muscle satellite cell sources for cultured meat: anatomical origin influences cellular properties and quality attributes
Abstract Muscle satellite cells are integral to muscle growth and regeneration, making them critical for cultured meat production. However, the influence of anatomical origin on porcine muscle satellite cells (PMSCs) for food applications remains underexplored. Here, we compared PMSCs from neck…