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BMJ Open Ophthalmology
Scopus
ISSN 2397-3269 · BMJ Publishing Group · 974 artikel di indeks
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Artikel Jurnal Teks lengkap
Effects of ascorbic acid on trabecular meshwork gene expression and collagen secretion
Objective Aqueous humour (AH) contains relatively high concentrations of vitamin C (ascorbate). AH drains out of the anterior chamber through the trabecular meshwork (TM) and, therefore, TM cells in vivo are routinely bathed in this antioxidant. Yet, most TM cells are cultured in vitro in media…
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Metastatic disease in conjunctival malignant melanoma: a retrospective analysis of 167 cases
Objective To analyse the data of a cohort of patients with conjunctival melanoma in order to analyse risk and guarding factors and to investigate the impact on metastatic disease with and without adjuvant therapy.Methods and analysis We have retrospectively analysed the impact of clinical aspects…
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Randomised, double-masked trial to compare the efficacy, safety and immunogenicity of the biosimilar aflibercept FYB203 with reference aflibercept in patients with neovascular age-related macular degeneration
Objective Biosimilars are helping to reduce the cost burden of treatment and widen patient access to therapies. This multicentre trial compared the efficacy, safety and immunogenicity of the biosimilar aflibercept FYB203 with reference aflibercept in patients with neovascular age-related macular…
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Artikel Jurnal Teks lengkap
Research on eye health 2000–2019: a global bibliometric analysis with a focus on equity
Objective To summarise global peer-reviewed primary research on eye health published from 2000 to 2019.Methods and analysis We used the ‘explode eye disease’ function on MEDLINE to obtain all articles reporting primary research studies on eye health published between 1 January 2000 and 31 December…
Juga tersedia di: DOAJ
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Artikel Jurnal
NLP-ROPCare: predicting retinopathy of prematurity with admission notes using natural language processing
Objectives Retinopathy of prematurity (ROP) is a leading cause of blindness in children worldwide, requiring more efficient models to help predict treatment-requiring ROP. Our study aimed to develop a new prediction model for ROP occurrence and severity, named NLP-ROPCare, using natural language…
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Selecting measures of visual function to classify diabetic retinopathy status: a cross-sectional study
Aim To identify combinations of up to three visual function tests with the best performance for classifying diabetic retinopathy (DR) severity stage. To describe in detail the measurements from a comprehensive set of visual function tests.Methods 1901 eyes (1032 participants) underwent nine visual…
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Evaluating reasoning large language models with human-like thinking in ophthalmic question answering
Objectives To evaluate the performance of reasoning large language models (LLMs) with human-like thinking in ophthalmic question answering.Methods We evaluated two state-of-the-art open-source reasoning LLMs (DeepSeek-R1 and QwQ-32B) and one conventional non-reasoning LLM (LLaMA-3.3-70B-Instruct)…
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Driver’s licence in an adult population with good vision: an exploratory study in two longitudinal very low birthweight cohorts
Objective To investigate whether being born preterm with very low birth weight (VLBW), lower best-corrected visual acuity (BCVA) or a history of a psychiatric or somatic diagnosis is associated with, or mediates, not having obtained a driver’s licence at adult age.Methods and analysis Potential…
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Ocular diseases and their association with mortality in intensive care unit patients: a retrospective cohort study from the MIMIC-IV database
Introduction Ocular diseases, though common in intensive care unit (ICU) patients, are often overlooked due to prioritisation of organ failure management. Their comorbidities, clinical features and prognostic effects require large-scale investigation.Measurements and main results This study used…
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Metformin and incidence of age-related macular degeneration in people with diabetes: a population-based 5-year case-control study
Objective Metformin has been identified as a potential treatment for age-related macular degeneration (AMD). Photographic screening for diabetic retinopathy provides an opportunity to conduct a case-control study with systematic AMD grading. We aimed to investigate associations between metformin…
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Safety and tolerability of avacincaptad pegol in combination with ranibizumab in treatment-naïve patients with neovascular age-related macular degeneration: results from a phase 1 and phase 2a study
Objective To assess the safety and tolerability of avacincaptad pegol (ACP), a Food and Drug Administration-approved therapy for geographic atrophy, administered in combination with ranibizumab, an approved therapy for neovascular age-related macular degeneration (nAMD), in patients with…
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Consensus on evidence gaps and unmet needs in childhood myopia: findings from a European Delphi study with eye care professionals and payers
Background/aims Childhood myopia is a growing global concern, associated with significant burdens. This study aimed to identify evidence gaps and unmet needs in childhood myopia management through a European Delphi panel involving eye care professionals (ECPs) with expertise in childhood myopia…
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Is metamorphopsia more important than visual acuity in vitreomacular interface disorders? A scoping review
Background Vitreomacular interface disorders are known to reduce vision-related quality of life (VR-QoL). This is due to both reduced visual acuity and metamorphopsia. In clinical practice, visual acuity is measured routinely, but quantitative measurements of metamorphopsia are less frequent. We…
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Intracameral pressure during capsulorhexis in cataract surgery using cohesive versus dispersive ophthalmic viscosurgical devices: a randomised trial
Objective To study the properties of different ophthalmic viscosurgical devices (OVDs) with respect to their ability to create and maintain high intraocular pressure (IOP) during the creation of a continuous curvilinear capsulorhexis (CCC) by comparing the drop in IOP before and after creation of…
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Retinal vascular alteration following surgical intraocular pressure reduction in primary angle closure disease
Aims To investigate retinal vascular geometric alterations following intraocular pressure (IOP)-lowering surgery in patients with primary angle closure disease (PACD) and determine associations between IOP reduction magnitude and retinal vascular parameters.Methods This retrospective…
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Forecasting regional disparities in cataract surgery demand and ophthalmologist supply in Japan: a prefecture-level forecasting study
Objective Cataracts are the leading cause of poor vision in Japanese adults. As Japan’s population is rapidly ageing, the demand for cataract surgery will continue to increase. Despite this, quantitative research evaluating both supply and demand of cataract surgery is lacking. The objective of…
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Charles Bonnet Syndrome: associations between psychosocial measures and visual hallucination characteristics in the visually impaired
Background/aims The emotional response to Charles Bonnet Syndrome (CBS) (visual hallucinations in individuals with sight loss) is associated with negative affect, suggesting a link between psychological measures and hallucination characteristics. This study set out to investigate whether the…
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Reduced haemorrhage during external medial orbital wall decompression with nasal packing containing vasoconstrictive agent
Objective In retrocaruncular medial decompression, the incision is small relative to the depth of the surgical space, and haemorrhage may obscure vision. Measures that minimise bleeding are most important to improve visualisation and facilitate the procedure. Despite this, there is no consensus…