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Scopus
ISSN 2397-9070 · Wiley · 1.304 artikel di indeks
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Artikel Jurnal
Eosinophilic Gastrointestinal Disease After Pediatric Organ and Bone Marrow Transplantation
ABSTRACT Background Previous studies have shown an increased prevalence of eosinophilic gastrointestinal disease (EGID) in pediatric liver and heart transplant recipients. However, EGID after other solid organ and bone marrow transplantations has not been extensively evaluated. Aims The purpose of…
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Artikel Jurnal
Effect of Butyrate‐Producing Enterobacteria and Proton Pump Inhibitors on Advanced Hepatocellular Carcinoma Treatment With Durvalumab and Tremelimumab
ABSTRACT Aim The gut microbiome modulates immune responses, and butyrate‐producing bacteria have been linked to improved immune checkpoint inhibitor (ICI) efficacy. Conversely, proton pump inhibitors (PPIs) may negatively impact ICI outcomes by altering gut microbiota. This study aims to elucidate…
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Artikel Jurnal
Pregnancy Outcomes and Disease Activity in Women With Inflammatory Bowel Disease in Qatar: A Retrospective Cohort Study
ABSTRACT Background Inflammatory bowel disease (IBD) commonly affects women of childbearing age and may complicate pregnancy. This study evaluated disease activity, treatment patterns, and pregnancy outcomes among women with IBD in Qatar. Materials and Methods Retrospective cohort study at a…
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Artikel Jurnal
Eosinophilic Esophagitis in the Middle East: Insight From a Comprehensive Systematic Review
ABSTRACT Background Eosinophilic esophagitis (EoE) is a chronic, immune‐mediated inflammatory disease of the esophagus, defined by esophageal dysfunction and dense eosinophilic infiltration (≥ 15 eosinophils per HPF) in biopsies, after exclusion of other causes. While its global incidence is…
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Artikel Jurnal
Differentiation of Gallbladder Adenomyomatosis and Polyps in a Western Cohort: Prevalence, Ultrasound Characteristics, and Diagnostic Challenges
ABSTRACT Background Gallbladder adenomyomatosis and polyps are common benign lesions that can mimic malignancy on imaging, often leading to unnecessary cholecystectomy. Despite frequent sonographic detection, the prevalence of adenomyomatosis in living cohorts remains poorly defined. Aim To…
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Artikel Jurnal
Impact of Gender and Race on Gastrointestinal Diseases in Patients With Parkinson's Disease: A Nationwide Analysis
ABSTRACT Background Gastrointestinal (GI) diseases are common non‐motor features of Parkinson's disease (PD), significantly impacting quality of life. The impact of racial and gender disparities in this population remains underexplored. This study examines the association of race and gender with GI…
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Artikel Jurnal
Esophageal Perforation in Zollinger–Ellison Syndrome: A Scoping Review of Management and Outcomes
ABSTRACT Esophageal perforation in Zollinger–Ellison syndrome (ZES) is an exceedingly rare and life‐threatening manifestation of gastrinoma‐related acid hypersecretion. While peptic ulceration and severe reflux are recognized complications of ZES, perforation represents the ultimate consequence of…
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Artikel Jurnal
Genetically Validated Immune Susceptibility Markers for Crohn's Disease: A Multi‐Omics Mendelian Randomization Analysis
ABSTRACT Background Crohn's disease (CD) is a chronic inflammatory bowel disorder with a multifactorial genetic, immune, and environmental basis, yet robustly validated therapeutic targets remain limited. We applied a multi‐omics Mendelian randomization (MR) framework and colocalization to…
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Artikel Jurnal
Dietary Characteristics Associated With High Defecation Frequency and Constipation in Japanese Adults: A Cross‐Sectional Study
ABSTRACT Aims The aim of this study was to evaluate the association between defecation frequency and dietary characteristics in adult men and women to identify factors associated with appropriate defecation frequency. Methods We performed a cross‐sectional study of 11,595 participants (n = 6142 men…
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Artikel Jurnal
Anti‐Tubercular Drug‐Induced Liver Injury: Current Understanding and Emerging Directions
ABSTRACT Most common adverse effect causing cessation of anti‐tubercular treatment (ATT) is drug‐induced liver injury (DILI) which is unpredictable due to its idiosyncratic nature. ATT is the most common cause of DILI and drug‐induced acute liver failure (ALF) in South East Asia. Spectrum of…
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Artikel Jurnal
Outcomes of Abdominal Tuberculosis Referred for Surgical Management in a Tertiary Care Center in Nepal
ABSTRACT Background While abdominal tuberculosis (ATB) is a great masquerader, it can cause significant morbidity and mortality. We aim to evaluate the presentation and management outcomes of patients with abdominal TB referred to us for surgical management. Methods This is a retrospective study of…
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Artikel Jurnal
Assessment of Circulating Tumor DNA for Early Detection of Hepatocellular Carcinoma in Alpha‐Fetoprotein–Negative Patients With Cirrhotic Nodules
ABSTRACT Aims Early detection is essential for improving hepatocellular carcinoma's (HCC) prognosis. However, the diagnostic performance of the current interventions remains unsatisfactory, particularly in patients with cirrhotic nodules. We aimed to develop a predictive model for the early…
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Artikel Jurnal
Frailty Diagnosed With the Clinical Frailty Scale Stratifies the Risk of Covert and Overt Hepatic Encephalopathy in Patients With Cirrhosis
ABSTRACT Aims Frailty predisposes patients with cirrhosis to hepatic encephalopathy (HE). This study aimed to evaluate the effect of frailty on risk stratification for covert HE (CHE) and overt HE (OHE) in patients with cirrhosis. Methods Hospitalized patients with cirrhosis and without history of…
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Artikel Jurnal
Association of Proton Pump Inhibitor and Potassium‐Competitive Acid Blocker Use With Discontinuation and Intolerance of Oral 5‐Aminosalicylic Acid in Patients With Ulcerative Colitis
ABSTRACT Aims Proton pump inhibitors (PPIs) and potassium‐competitive acid blockers (PCABs) are widely used for acid‐related disorders. Recent studies have raised concerns that acid suppression may alter gut microbiota and drug pharmacokinetics, potentially influencing therapeutic outcomes in…
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Artikel Jurnal
Integration of Endocuff‐Assisted and Computer‐Aided Colonoscopy: A Meta‐Analysis of Randomized Controlled Trials
ABSTRACT Introduction Colorectal cancer (CRC) is a leading cause of cancer‐related deaths, with missed lesions during colonoscopy contributing to increased mortality. AI‐assisted computer‐aided detection (CADe) systems help reduce adenoma miss rates, and their integration with mucosal exposure…
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Artikel Jurnal
Targeting C12ORF49‐Mediated Ferroptosis in Hepatocellular Carcinoma
ABSTRACT Hepatocellular carcinoma (HCC) remains a leading cause of cancer‐related mortality worldwide, underscoring the urgent need for novel therapeutic strategies. Recent studies have highlighted the pivotal role of ferroptosis, an iron‐dependent form of regulated cell death driven by lipid…
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Artikel Jurnal
Therapeutic Drug Monitoring of Vedolizumab Levels During Maintenance in Inflammatory Bowel Disease (MOVE‐IBD)
ABSTRACT Background and Aims Therapeutic drug monitoring (TDM) of non anti‐TNF biologics is not well established in clinical practice. We aimed to clarify the association between VTL and remission in our cohort of maintenance vedolizumab patients using objective markers of disease activity to see…
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Artikel Jurnal
Comparison of Endoscopic Therapies for Small Rectal Neuroendocrine Tumors: Endoscopic Muscularis Superficialis Dissection Versus Endoscopic Submucosal Dissection
ABSTRACT Background and Aim Rectal neuroendocrine tumors (rNETs) often exhibit submucosal tumor‐like growth. While endoscopic submucosal dissection (ESD) is widely used, it carries a risk of positive vertical margins, often necessitating repeated surveillance and imposing both financial and…
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