1.205 hasil
Menampilkan 1–20 · 0,19 detik · RSS
Clinical and Translational Radiation Oncology
Scopus
ISSN 2405-6308 · Elsevier · 1.205 artikel di indeks
-
Artikel Jurnal
Surgery followed by adjuvant radiotherapy versus definitive radiotherapy for locally advanced squamous cell carcinoma of the pharynx and larynx: a propensity score-matched analysis
Aim : Locally advanced squamous cell carcinoma (SCC) of the pharynx and larynx is commonly treated with either primary surgery followed by adjuvant radiotherapy (RT) or definitive RT with or without concurrent systemic therapy. Comparative outcome data between these treatment strategies remain…
-
Artikel Jurnal
CyberKnife SBRT plus lenvatinib and tislelizumab versus doublet systemic therapy for hepatocellular carcinoma with macrovascular invasion: A real-world IPTW-adjusted study
Background & purpose: Macrovascular invasion (MVI) in hepatocellular carcinoma (HCC) confers extremely poor prognosis. While lenvatinib plus tislelizumab is an active targeted-immunotherapy regimen, local control of tumor thrombus remains suboptimal. Stereotactic body radiotherapy (SBRT) delivered…
-
Artikel Jurnal
“Clinical outcomes of definitive interstitial/hybrid high-dose-rate and pulsed-dose-rate interventional radiotherapy (brachytherapy) for non-melanoma skin cancer: A single-center retrospective analysis”
Purpose: To evaluate clinical outcomes and toxicity of definitive interstitial or hybrid interventional radiotherapy (IRT; brachytherapy) using high-dose-rate (HDR) or pulsed-dose-rate (PDR) techniques for non-melanoma skin cancer (NMSC) unsuitable for standard superficial treatment. Materials and…
-
Artikel Jurnal
Ablative magnetic resonance–guided radiation for gastrointestinal neuroendocrine tumors: assessing local control and toxicity
Background: Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are an indolent subset of neuroendocrine neoplasms with a propensity to metastasize. In the case of oligoprogression, locoregional therapies are considered but may not be suitable for all patients. Stereotactic body radiotherapy…
-
Artikel Jurnal
Treat the patient, not the MRI: Lessons from low-dose radiotherapy for plantar fasciitis
The recent study by Novo-Rigueiro et al. adds important prospective evidence for low-dose radiotherapy (LDRT) in refractory plantar fasciitis. After failure of conservative treatment and extracorporeal shock wave therapy, patients showed durable improvements in pain, function, and health-related…
-
Artikel Jurnal
Gender disparities in academic radiation oncology research: A narrative review
Introduction: Despite rising numbers of women in radiation oncology (RO), they remain under-represented in academic leadership and research. This narrative review assesses gender disparities in academic RO. Materials and methods: PubMed/MEDLINE and Europe PMC were searched in August 2026 for…
-
Artikel Jurnal
Prolonging breath-hold duration in radiotherapy using cognitive engagement
Purpose/objective: Deep inspiration breath-hold (DIBH) is commonly used in breast cancer radiotherapy to decrease cardiac radiation exposure. Using high-flow nasal oxygen and hyperventilation we achieved voluntary long deep inspiration breath-holds (L-DIBH) exceeding 3 min. Substantial variability…
-
Artikel Jurnal
36.25 Gy versus 40 Gy in five fractions of curative stereotactic body radiotherapy for prostate cancer: a propensity score-matched analysis
Background: This study aimed to determine whether 36.25 Gy was inferior to 40 Gy in terms of prostate-specific antigen (PSA) recurrence following stereotactic body radiation therapy (SBRT) for prostate cancer. Methods: We retrospectively reviewed the medical records of 863 consecutive patients with…
-
Artikel Jurnal
Reirradiation of recurrent brain tumors: a review by the ESTRO CNS Focus Group
Purpose: Reirradiation has become an area of increasing clinical and scientific interest, particularly in neuro-oncology. This non-systematic review on central nervous system (CNS) tumors by the CNS focus group of the European Society for Radiotherapy and Oncology provides a pragmatic synthesis of…
-
Artikel Jurnal
The value of community engagement in the ESTRO–EORTC OligoCare project: A quantification of the in-kind contributions
Background: The OligoCare cohort constitutes the largest prospective dataset evaluating metastasis-directed radiotherapy in oligometastatic disease worldwide. Although the project received financial support for central coordination, no financial compensation for the operational involvement of the…
-
Artikel Jurnal
MR-guided ultra-hypofractionated radiotherapy for early-stage glottic cancer: A phase I feasibility study
Introduction: Ultra-hypofractionation for early-stage glottic cancer reduces the number of hospital visits, but requires precise delivery to minimize the risk of radiation-induced toxicity. Magnetic Resonance (MR)-guided radiotherapy is a delivery technique that enables visualization of the tumor…
-
Artikel Jurnal
PACTUS: A two-week radiotherapy regimen for patients with anal squamous cell carcinoma unsuitable for standard chemoradiotherapy—a retrospective single-centre experience
Introduction: Anal squamous cell carcinoma (ASCC) is rare, and optimal treatment for patients unsuitable for definitive chemoradiotherapy remains undefined. This study describes PACTUS (Palliative Anal Cancer Treatment Uppsala Style), a two-week radiotherapy regimen designed for symptom relief and…
-
Artikel Jurnal
Concurrent versus sequential immune checkpoint inhibition in the neoadjuvant treatment of resectable esophageal squamous cell carcinoma: a systematic review and meta-analysis
Background: Immune checkpoint inhibitors (ICIs) are increasingly integrated into the neoadjuvant treatment of resectable esophageal squamous cell carcinoma (ESCC), yet the optimal timing of ICI administration remains undefined. We conducted the first systematic review and meta-analysis directly…
-
Artikel Jurnal
Cumulative oesophageal dose and risk of high-grade toxicity in thoracic re-irradiation: a dose/toxicity analysis
Background and purpose: Re-irradiation (re-RT) in recurrent thoracic cancer is being performed more often and can cause severe toxicity. Information is lacking on safe re-irradiation dose constraints. We modelled the relationship between cumulative oesophageal dose and grade 3 or worse (≥G3)…
-
Artikel Jurnal
Prospective evaluation of liver cancer volumes on non-contrast 1.5 T MR Linac imaging
Background: The 1.5 T MR-Linac (MRL) provides a platform for online adaptive stereotactic body radiation therapy (SBRT). This study aims to compare gross tumor volume (GTV) on multiphasic (MP) CT and MR simulation imaging versus non-contrast MRL images and to measure changes in GTV during SBRT…
-
Artikel Jurnal
Evaluating the efficacy and immunological impact of combined ICIs and SBRT in HCC: A narrative literature review
Hepatocellular carcinoma (HCC) represents one of the leading contributors to cancer-related deaths, with the majority of patients diagnosed at stages where curative treatment is no longer possible. Combining stereotactic body radiotherapy (SBRT) with immune checkpoint inhibition (ICI) has gained…
-
Artikel Jurnal
Iron deficiency in patients undergoing radiotherapy: Prevalence and clinical characteristics
Purpose: Anemia in patients undergoing radio-chemotherapy (RCTx) is often driven by iron deficiency and can impact quality of life and therapy outcomes. This study aimed to evaluate how RCTx affects iron metabolism and identify additional influencing factors. Methods: We conducted a retrospective…
-
Artikel Jurnal
Vestibular dose predicts toxicity in stereotactic radiosurgery for vestibular schwannomas
Introduction: Stereotactic radiosurgery (SRS) provides excellent tumor control in small and medium vestibular schwannomas (VS), but its impact on the vestibular system remains uncertain. This study examines the effects of SRS on subjective vestibular symptoms, vestibular function, and potential…
-
Artikel Jurnal
Mini-GRID enhances survival and reduces toxicity in an orthotopic murine model of oral squamous cell carcinoma: A proof-of-concept study
Background and purpose: Oral squamous cell carcinoma (OSCC) remains a major clinical challenge, with limited therapeutic options and poor outcomes. Among the emerging approaches to address this unmet need, spatially fractionated radiotherapy (SFRT) using mini-GRID patterns has emerged as a…
-
Artikel Jurnal
Multimodal conservative local treatment based on combined brachytherapy and external beam radiation therapy for paediatric pelvic and perineal rhabdomyosarcoma
Purpose: In pediatric pelvic or perineal rhabdomyosarcoma, organ preservation rates are high following neoadjuvant chemotherapy. We assessed the impact of combining external beam radiation therapy (EBRT) and brachytherapy (BT) on local control and functional outcomes. Methods: We retrospectively…
Menampilkan maksimal 50 halaman. Persempit pencarian dengan filter untuk hasil yang lebih spesifik.