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Physics and Imaging in Radiation Oncology
Scopus
ISSN 2405-6316 · Elsevier · 1,006 articles in the index
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Journal Article
A novel approach for spot boosting selection and treatment plan optimization to enhance prompt gamma monitoring of proton therapy
Background and Purpose:: Despite continuous progress, proton therapy remains challenged by delivery uncertainties. In vivo monitoring can help address these limitations. Prompt-gamma (PG) imaging is a monitoring technique suitable for adaptive particle therapy, though it suffers from low signal at…
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Journal Article
Robustness evaluation of carbon ion radiotherapy for ventricular tachycardia
Favorable clinical outcomes of carbon-ion radiotherapy (CIRT) for ventricular arrhythmia have been reported, and optimal treatment strategies are being explored. We assessed the robustness of CIRT plans against cardiac motion in ventricular tachycardia. Electrocardiographic (ECG)-gated computed…
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Journal Article
Dose comparison of proton beam therapy with and without a multileaf collimator in the treatment of multiple hepatocellular carcinoma
Background and purpose: Proton beam therapy (PBT) offers dosimetric advantages over conventional photon-based radiation therapy in treating hepatocellular carcinoma (HCC) because it more effectively spares normal liver tissue. This study investigated the potential benefits of incorporating a…
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Journal Article
Treatment planning comparison of focused very high energy electron and volumetric modulated arc therapy
Background and purpose: Very high energy electron (VHEE) radiotherapy gained interest owing to technical advances and its potential for FLASH radiotherapy. Magnetically focused VHEE (fVHEE) beams showed promises in preliminary investigations in water phantoms. However, inverse treatment planning…
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Journal Article
Evaluation of the accuracy of a surface-guided radiotherapy system for patient positioning in radiotherapy of breast cancer
Background and Purpose: The accuracy of a surface-guided radiotherapy (SGRT) system for patient positioning in free-breathing breast cancer radiotherapy (RT) was evaluated against cone-beam computed tomography (CBCT)-based image registration. Materials and Methods: A total of 106 treatment…
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Journal Article
Balancing dose preservation and treatment efficiency in motion-managed magnetic resonance image-guided radiotherapy of pancreatic cancer
Background and purpose: Active motion management (AMM) during magnetic resonance image (MRI)-guided pancreatic cancer radioablation enables tight planning target volume (PTV) margins but may prolong treatment. AMM strategies include beam gating and drift correction, which respectively interrupt or…
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Journal Article
An automated planning optimization framework for cervical intensity-modulated radiation therapy using voxel dose prediction and adaptive parameter tuning
Knowledge-based planning typically lacks mechanisms to manage prediction uncertainties. We developed an automated framework integrating voxel-dose prediction with adaptive optimization to overcome this limitation. For 27 cervical intensity-modulated radiation therapy (IMRT) cases, voxel-dose…
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Journal Article
Deep learning-based head and neck deformable image registration using spatio-temporal analysis and self attention
Background and purpose: Significant anatomical changes during head and neck cancer (HNC) radiotherapy challenge accurate dose delivery. Deformable image registration (DIR) is essential for adaptive radiotherapy (ART), yet conventional methods are too slow for online clinical use. This study…
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Journal Article
Effects of breath-hold reproducibility on proton and photon lung cancer stereotactic body radiotherapy
Background and purpose:: Breath-hold can mitigate respiratory motion in lung cancer radiotherapy. Reduced motion could be especially beneficial for proton therapy which is more sensitive to geometrical perturbations than photon therapy. However, failure to reproduce the breath-hold tumor position…
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Journal Article
The impact of bladder and rectal dynamics on prostate and seminal vesicles intrafraction motion and deformation in radiotherapy
Introduction: Treatment uncertainties influenced by organ intrafraction motion complicate the widespread adoption of hypofractionated radiotherapy. This study aims to identify imaging features on pre-treatment magnetic resonance imaging (MRI) scans that describe prostate and seminal vesicle (SV)…
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Journal Article
X-ray beam quality checks of a magnetic resonance-guided linear accelerator with its on-board megavoltage imager
This study presents a method for fast and low-cost X-ray beam quality checks of magnetic resonance-guided radiotherapy (MRgRT) linacs using the on-board megavoltage imager (MVI). On four linacs from two clinics, beam quality was varied (quantified by ionization chamber measurements) and correlated…
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Journal Article
Dental metal artifacts in magnetic resonance-based synthetic computed tomography for brain radiotherapy: Impact on dose, patient setup, and geometric distortion
Background and purpose: Magnetic resonance (MR)-based synthetic computed tomography (sCT) can improve target and organs-of-interest delineation in brain radiotherapy. However, metallic implants may cause anatomical inconsistencies, dose inaccuracies, and distortions. This study evaluates the impact…
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Journal Article
Cardiac device motion tracking from kilovoltage projections during stereotactic arrhythmia radioablation
Background and purpose: Cardiac and respiratory motion present a challenge to accurate dose delivery during stereotactic arrhythmia radioablation (STAR). This study investigated a motion tracking method using kilovoltage (kV) images on a gantry‐mounted linear accelerator during STAR. Materials and…
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Journal Article
Potential of margin reduction for cervical cancer radiotherapy in an online adaptive image-guided workflow
Background and purpose: Adaptive radiotherapy (ART) manages anatomical variations through real-time plan adjustments. Herein, we aimed to evaluate the efficacy of ART in improving target coverage and reducing organ-at-risk (OAR) irradiation doses in cervical cancer. Materials and methods: A…
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Journal Article
Multicenter evaluation of planning quality in intracranial stereotactic radiotherapy for brain metastases
Background and purpose: Stereotactic radiotherapy (SRT) is a standard approach for treating multiple brain metastases. However, variation in planning practices may impact treatment quality. This study assessed planning consistency and dose–volume–based outcomes across radiation oncology centers…
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Journal Article
Patient-specific fine-tuning of a self-distilled transformer model for normal tissue segmentation in abdominal magnetic resonance guided adaptive radiotherapy
Background and Purpose:: Accurate segmentation of organs-at-risk is critical for adaptive Magnetic Resonance guided radiotherapy (MRgRT) in upper gastrointestinal (GI) treatments. Large anatomical variations pose challenges for automated segmentation methods, requiring considerable manual editing…
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Journal Article
A combined automatic organ at risk contouring and synthetic Computed Tomography solution for pelvic Magnetic Resonance-only radiotherapy
Background and Purpose:: Magnetic Resonance (MR)-only radiotherapy improves treatment accuracy and efficiency but requires a synthetic Computed Tomography (sCT) for dose calculations. Automatic MR-based Organs At Risk (OARs) contouring could further improve consistency and efficiency. A combined…
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Journal Article
Standardising image registration and dose mapping for thoracic reirradiation: A national multi-centre benchmarking study
Background and purpose: Safe delivery of high-dose reirradiation depends on robust evaluation of previously delivered dose on current patient anatomy. This study aims to assess the variability of 1) rigid (RIR) and deformable (DIR) image registration, and 2) dose-mapping based on RIR or DIR, as…
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Journal Article
Automated evaluation of organ sparing in prostate stereotactic body radiation therapy using dose-gradient metrics
Background and purpose: Traditional dose-volume histogram (DVH) metrics used in radiotherapy plan evaluation lack spatial information and are sensitive to organ volume variations. This study investigated the use of Dose Gradient Curves (DGCs) as a robust, volume-independent alternative for…
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