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eNeurologicalSci
Scopus
ISSN 2405-6502 · Elsevier · 555 artikel di indeks
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Artikel Jurnal
Identification of myokymia in adult-onset hereditary spastic paraplegia type 79A: Implications for the phenotypic spectrum
Spastic paraplegia type 79 (SPG79) is a rare form of hereditary spastic paraplegia caused by variants in ubiquitin C-terminal hydrolase L1 (UCHL1). SPG79B, an early-onset autosomal recessive subtype, frequently presents with lower motor neuron involvement, with myokymia as a characteristic feature…
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Hypertensive brainstem encephalopathy with isolated headache and blurred vision: A case report
Background: Headache with papilledema is a critical neurological symptom that necessitates prompt evaluation for underlying central nervous system pathology. While often associated with conditions such as aneurysmal subarachnoid hemorrhage, hypertensive emergencies can also present with similar…
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Artikel Jurnal
Factors associated with the progression of disability (EDSS) among MS patients
Background: Multiple sclerosis is a chronic, inflammatory, autoimmune disease of the central nervous system. Accumulating neurological disability has a substantial impact on the lives of patients with MS. The Expanded Disability Status Scale is a method of quantifying disability in MS. Objective…
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Association between DATSCAN-derived dopaminergic activity and cognitive performance and quality of life in Parkinson's disease: A cross-sectional study
Background: Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor and non-motor symptoms that substantially affect quality of life (QoL). While dopaminergic dysfunction is central to PD pathology, the cross-sectional relationship between striatal dopaminergic activity and…
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Unexpected infectious complication following AVM embolization: E. coli brain abscess
Background: Brain arteriovenous malformations (AVMs) are rare vascular anomalies managed with surgery, radiosurgery, or endovascular embolization. Post-embolization intracranial infections are extremely uncommon, especially Escherichia coli abscesses in immunocompetent adults. Case presentation: We…
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Construct validity of the timed 25-foot walk and robustness of clinical benchmarks in multiple sclerosis: exploratory analyses of TEAMS study
Background: The Timed 25-Foot Walk (T25-FW) is a widely used performance measure of ambulatory disability in multiple sclerosis (MS). Fewer studies have examined its construct validity relative to patient-reported outcomes or assessed robustness of previously proposed benchmarks in large cohorts…
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Nitrous oxide–related neurotoxicity: Clinical features, key investigations, and a proposed diagnostic approach from a single-center cohort
Background: Recreational use of nitrous oxide (N2O) is a growing public health concern. Its neurological complications include peripheral neuropathy and posterior column myelopathy. Our study aims to characterize the clinical, laboratory, and radiological features of N2O neurotoxicity, and to…
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Artikel Jurnal
Appropriateness of oral anticoagulant therapy and associated factors among hospitalized atrial fibrillation patients with the CHA2DS2-VASc score of 1 (beyond sex)
Background: Atrial fibrillation (AF) is the most common cardiac rhythm disturbances associated with increased risks of mortality. Oral anticoagulant (OAC) reduces AF-related strokes. However, the pattern of OAC use among AF patients is unknown in Ethiopia. This study evaluated the appropriateness…
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Prognostic value of serial IL-6 and NSE measurements in acute ischemic stroke patients undergoing mechanical thrombectomy
Background: Despite major advances in acute stroke therapy, particularly mechanical thrombectomy (MT) for large-vessel occlusion, predicting outcomes in acute ischemic stroke (AIS) remains challenging. Secondary injury mechanisms such as neuroinflammation and neuronal damage contribute…
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Fractures beyond spasms: Progressive encephalomyelitis with rigidity and myoclonus associated with GABA-linked bone fragility
Progressive encephalomyelitis with rigidity and myoclonus (PERM) is a rare and severe form of stiff-person spectrum disorders, typically associated with painful spasms, brainstem involvement, and autonomic dysfunction. Previous reports have described fractures as an uncommon but recognized…
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Hereditary transthyretin amyloidosis mimicking ALS: First genetically proven case report from Saudi Arabia
Background: Hereditary transthyretin amyloidosis (ATTRv) is a systemic disorder that may mimic motor neuron disease (MND), leading to misdiagnosis and delayed access to disease-modifying therapies. Case report: We report the first genetically confirmed case of ATTRv mimicking amyotrophic lateral…
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Listeria rhombencephalitis in an alcoholic man; A case report and review of literature
Listeria infections are uncommon in our clinical practice and often overlooked as a differential diagnosis. It is also difficult to uncover due to presentation with a variety of non-specific clinical signs and symptoms, that could mimic other conditions. In our case report, we discuss a rare and…
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Building confident cohesive stroke response teams: Design, implementation and outcomes of a stroke code simulation training program for interprofessional teams in LMIC
Introduction: Training in LMICs for hyperacute stroke relies on didactic methods. This study describes the development and evaluates the impact of a high-fidelity simulation-based interprofessional stroke code training course in Pakistan, aiming to improve teamwork, communication, and clinical…
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The role of hyperbaric oxygen therapy for treating spinal cord injury: Mechanisms, considerations, and research outcomes
Spinal cord injury (SCI) presents formidable challenges, with current regenerative treatments such as stem cell therapy and spinal stimulation showing inconsistent results in clinical trials. Advances in understanding the pathophysiology of SCI have directed regenerative strategies toward reducing…
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Associations of glycated hemoglobin with etiology, lesions, and outcome of ischemic stroke: Japan Stroke Data Bank
Background: Despite abundant evidence linking hyperglycemia to stroke, its heterogeneous effects across stroke etiologies and lesions remain unclear. We examined the associations between admission glycated hemoglobin (HbA1c) levels and stroke subtypes, lesions, and functional outcomes. Methods…
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Pharyngeal electrical stimulation for the treatment of dysphagia in Wallenberg syndrome: A FEES-based case analysis
Swallowing is regulated by cortical networks and the caudal brainstem. Damage to central pattern generators, commonly seen after stroke, can result in severe dysphagia with limited treatment options. Pharyngeal electrical stimulation (PES) presents a promising therapy as it may enhance sensory…