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Journal

Heliyon

Scopus

ISSN 2405-8440 · Elsevier · 43,187 articles in the index

  1. Journal Article

    Microbial landscape transformation in burn wounds as a predictor of delayed healing

    Inara Abashidze; Irina Savitskaya

    Heliyon, Vol. 12 No. 2 · 2026 · English · DOAJ Scopus

    Goal: Dynamic analysis of the transformation of the microbial landscape of burn wounds at different stages of hospitalization as an objective assessment of predictors of their prolonged healing. Materials and methods: This was a prospective, observational, single-center longitudinal study with…

  2. Journal Article

    Niosomal nanocarriers for gemcitabine in treatment of MDA-MB-231, AsPC-1 and Calu-6 cells: investigations in vitro and in vivo

    Aliyeh Ranjbar; Mohammadreza Ajdari; Khashayar Karimian et al.

    Heliyon, Vol. 12 No. 2 · 2026 · English · DOAJ Scopus

    Gemcitabine (GEM) is a cytotoxic chemotheraputic agent employed for treatment of different cancers. GEM-loaded nanoniosomes were synthesized and characterized to enhance efficacy and weaken its side effects by decreasing half-maximal inhibitory concentration (IC50) value. The nanoniosomes were…

  3. Journal Article

    Using functional near-infrared spectroscopy to study neurocognitive function in adult survivors of childhood acute lymphoblastic leukemia, an exploratory study

    Simon Skau; Marianne Jarfelt; Gustaf Glavå et al.

    Heliyon, Vol. 12 No. 2 · 2026 · English · DOAJ Scopus

    Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy. Due to the drastic increase in survivor rate over the last 50 years, long-lasting treatment effects on moods and neurocognitive function have become a current issue. Most studies relating to the effects of treatment in ALL…

  4. Journal Article

    Modified atmospheric packaging an emerging non-invasive packaging technique for strawberry preservation- a review

    Mehraj Fatema Z. Mulla; Tigist Shonte; Lorraine Foley et al.

    Heliyon, Vol. 12 No. 2 · 2026 · English · DOAJ Scopus

    Strawberries are highly perishable due to their soft texture, high respiration rate, and susceptibility to microbial spoilage. Modified Atmosphere Packaging (MAP) has emerged as a non-invasive preservation strategy to address these limitations while retaining quality. This review aims to critically…

  5. Journal Article

    Ninjin-yoei-to improves survival and attenuates cachexia by preserving muscle and body weight in murine models of lung cancer and fibrosis

    Takafumi Shigekusa; Hironobu Tsubouchi; Shigehisa Yanagi et al.

    Heliyon, Vol. 12 No. 2 · 2026 · English · DOAJ Scopus

    In chronic lung diseases like lung cancer and idiopathic pulmonary fibrosis, cachexia often develops, manifesting as sustained weight decline with muscle wasting. Loss of skeletal muscle mass in a cachectic condition has been associated with breathlessness, functional limitation, and poor…

  6. Journal Article

    The effect of prenatal sensory stimulation on the parvalbumin neurons in entopallium and visual Wulst

    A. Morandi-Raikova; R. Aydın; C.D. Corrales-Parada et al.

    Heliyon, Vol. 12 No. 2 · 2026 · English · DOAJ Scopus

    Conserved genetic mechanisms participate in developing brain asymmetries in vertebrates, but the effect of prenatal sensory stimulation on lateralised neural circuits is less understood. In birds, lateralisation emerges from the interaction of genetic factors and prenatal experience. Light exposure…

  7. Journal Article

    Deep learning model design for ECG-based prediction of sex and ventricular dysfunction: A technical exploration of CNN and transformer architectures

    Michal Cohen-Shelly; David Hochstein; Noam Barda et al.

    Heliyon, Vol. 12 No. 2 · 2026 · English · DOAJ Scopus

    Background and objective: Artificial intelligence (AI) based analysis of electrocardiogram (ECG) signals has become a powerful tool for predicting clinically important attributes such as sex and cardiac function. The growing use of wearable ECG technologies has increased interest in optimizing deep…

  8. Journal Article

    Anchoring permits kelp to acquire an ecological niche in coastal oceans: A model analysis

    Meng Gao; Allen J. Milligan; Curtis Deutsch et al.

    Heliyon, Vol. 12 No. 2 · 2026 · English · DOAJ Scopus

    Kelps (brown algae of the order Laminariales) are foundation species in coastal temperate oceans. As ecosystem engineers, they moderate local environments, provide habitats and food, and shape community structure. Despite their high rates of primary production, kelps overall growth rates are lower…

  9. Journal Article

    Marine-derived prospective antibiotic armamentarium: From anti-quorum sensing to anti-biofilm and anti-biofouling biometabolites

    Chowdhury Alfi Afroze; Md Nasir Ahmed; Rownak Jahan et al.

    Heliyon, Vol. 12 No. 2 · 2026 · English · DOAJ Scopus

    Antibiotics have been a significant advancement in medical science in recent decades. However, they are now creating drug-resistant pathogens worldwide due to the overuse and misuse of antibiotics in human, livestock, and crop health. According to the WHO's 2019 report, around 700,000 die worldwide…

  10. Journal Article

    Designing class discrepancy-guided sub-band filter using common frequency pattern for preprocessing EEG signals in MI-BCIs

    Ardalan Faezmehr; Ashkan Farrokhi; Vahid Shalchyan et al.

    Heliyon, Vol. 12 No. 2 · 2026 · English · DOAJ Scopus

    Motor imagery-based brain-computer interfaces (MI-BCI) using electroencephalogram (EEG) signals translate brain activity into control commands for output devices. Nowadays, BCI systems with fewer electrodes have gained attention; however, designing efficient feature extraction algorithms remains…

  11. Journal Article

    Status of qualitative and semi-quantitative workplace safety risk assessment research in Iran: A scoping review

    Fazel Rajabi; Mehdi Jahangiri; Aida Haghighi et al.

    Heliyon, Vol. 12 No. 2 · 2026 · English · DOAJ Scopus

    Background: Despite the widespread use of qualitative and semi-quantitative workplace safety risk assessment (WSRA) techniques as the main means of protecting employees in Iran, and despite the numerous applied studies that have been conducted, there is a lack of dedicated and comprehensive…

  12. Journal Article

    High diversity of Achromobacter sp. isolation from children with CF, a retrospective case-control study

    N. Antoun; H. Marchandin; V. Houdouin et al.

    Heliyon, Vol. 12 No. 2 · 2026 · English · DOAJ Scopus

    Background: Achromobacter spp. are opportunistic pathogens in cystic fibrosis. Recent studies have suggested that colonization by Achromobacter is associated with adverse effects on respiratory function. However, this is still understudied in children, as is the relative involvement of different…

  13. Journal Article

    Success of mechanical application of Chondrostereum purpureum by two different cutting heads

    Leena Hamberg; Ville Kankaanhuhta

    Heliyon, Vol. 12 No. 2 · 2026 · English · DOAJ Scopus

    In young boreal forests, naturally grown hardwoods are usually abundant, restricting the growth of cultivated conifers. Cutting only is inefficient due to quick resprouting of hardwoods, and therefore biological sprout control by using a decay fungus Chondrostereum purpureum (Pers. Ex Fr.) Pouzar…

  14. Journal Article

    Gold nanoparticle-based lateral flow immunoassay for detection of urinary 8-hydroxy-2ʹ-deoxyguanosine in preterm infants: A promising tool for pain-free, low-cost, and bedside screening of retinopathy of prematurity

    Abilash Gangula; Varsha Srinivasan; Shreya Ghoshdastidar et al.

    Heliyon, Vol. 12 No. 2 · 2026 · English · DOAJ Scopus

    Purpose: The clinical gold standard for screening of retinopathy of prematurity (ROP) in preterm infants involves binocular indirect ophthalmoscopy (BIO), an expensive, stressful, and not easily accessible procedure. In this study, we present the development of gold nanoparticle-based lateral flow…

  15. Journal Article

    A brief provision of non-alcoholic beverages reduces alcohol consumption: A pilot, single-arm study

    Shohei Dobashi; Ayako Kikuchi; Go Saito et al.

    Heliyon, Vol. 12 No. 2 · 2026 · English · DOAJ Scopus

    Our previous study demonstrated that providing three cases of non-alcoholic beverages on separate occasions significantly reduced alcohol consumption among heavy drinkers. However, interventions with reduced costs are required, particularly for health promotion in the workplace. Therefore, we…

  16. Journal Article

    Bridging the gap or widening the divide? Municipal decision-makers’ perceptions of healthcare digitalization in shrinking rural regions

    Annamari Kiviaho; Johannes Einolander

    Heliyon, Vol. 12 No. 2 · 2026 · English · DOAJ Scopus

    Digital healthcare is expected to address many societal problems, particularly those related to an aging and declining population. It is believed to increase people's well-being and improve health and quality of life by enhancing access to these services, and thus also increase equality. However…

  17. Journal Article

    Green manure boosts biomass, essential oils, and chemical constituents in Origanum majorana L.: a sustainable fertilization approach

    Jandeilson Pereira dos Santos; Rafael Marlon Alves de Assis; Jeremias José Ferreira Leite et al.

    Heliyon, Vol. 12 No. 2 · 2026 · English · DOAJ Scopus

    Green manure (GM) serves as an alternative to animal manure and organic compounds. Its use in sustainable agricultural practices helps enhance soil fertility and structure. Thus, this study aims to evaluate the potential of Cajanus cajan as a green manure to enhance the vegetative growth, essential…

  18. Journal Article

    The optimization of waste recycling and material flow cost in zero-emission intensive pig farming

    Duong Mai Linh; Tran Trung Kien; Nguyen Thi Phuong Thao et al.

    Heliyon, Vol. 12 No. 2 · 2026 · English · DOAJ Scopus

    Reducing greenhouse gas emissions and minimizing waste recovery costs are essential in intensive pig farming. In this study, an integrated system combining commercial intensive pig farming, rice cultivation, and biochar production in the same area leading to zero emissions goal was implemented in…

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