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Jurnal Farmasi dan Ilmu Kefarmasian Indonesia
ISSN 2406-9388 · Faculty of Pharmacy, Universitas Airlangga · 150 articles in the index
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Journal Article
Anti-Hepatitis C Virus Activity of Various Indonesian Plants from Balikpapan Botanical Garden, East Borneo
Background: Hepatitis C Virus infection is a serious health problem that leads to chronic liver disease, liver cirrhosis, hepatocellular carcinoma, which causes high morbidity. Direct-Acting Antiviral Agents have been used as anti-hepatitis C Virus therapy. However, it was covered only in limited…
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Journal Article
Synthesis and Antiplatelet Activity of 4-Hidroxy-3-Methoxycinnamic Acid
Background: Cinnamic acid and its derivatives have been widely studied for their efficacy because of the pharmacological effect on good health and well being. Microwave irradiation is more time effective to synthesize than conventional heating method because it conducts heat faster and shortens the…
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Journal Article
Detection of Potentially Inappropriate Medication in Elderly Outpatient Based on The Beer’s Criteria 2019
Background: Elderly patients generally have more than one disease, so they need several drugs to treat the condition and Potentially Inappropriate Medication (PIM). Objective: This study aimed to examine the inaccuracy of prescription drugs in the elderly using Beer's criteria 2019. Methods: The…
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Journal Article
Antidiabetic Activity of Ethanolic Extract of Kale (Brassica oleracea var. sabellica)
Background: Diabetes Mellitus is a disease caused by a disruption of the pancreas in producing insulin. The International Diabetes Federation (IDF) organization identified ten countries that have the highest cases of Diabetes Mellitus. Indonesia is ranked 7th out of 10 countries and is the only…
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Journal Article
Physicochemical Characteristics, Stability, and Irritability of Nanostructured Lipid Carrier System Stabilized with Different Surfactant Ratios
Background: One of the vital variables affecting the stability and the characteristics of the Nanostructured Lipid Carrier (NLC) is the surfactant concentration. Using the two combinations of surfactants can cause higher stability and a better characteristic of NLC. Tween 80 and Span 20 are anionic…
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Journal Article
Cost of Illness Type 2 Diabetes Mellitus Outpatient BPJS on Malang City Health Center
Background: Type 2 diabetes mellitus is a progressive illness that impacts the costs borne by patients. The Cost of Illness method can be used further to analyze the medical expenses for type 2 diabetes mellitus. Objective: Determine the annual total cost of type 2 diabetes mellitus outpatients in…
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Journal Article
Molecular Docking of Active Compound of Lavandula angustifolia Mill Essential Oil against N-methyl-D-aspartate (NMDA) Receptor
Background: Lavender oil is widely known to possess a relaxant effect to relieve stress, anxiety, and depression. Linalyl acetate, linalool, geranyl acetate, and β-caryophyllene were the major constituents of lavender oil that potentially act on NMDAR (N-methyl-d-aspartate receptors), and emerging…
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Journal Article
Potential Drug–Drug Interactions in Ambulatory Patients with Hypertension: a Retrospective Study
Background: Patients with cardiovascular diseases (CVD) are vulnerable to experiencing drug-drug interactions (DDIs). DDIs are a concern among patients receiving multiple drug regimens but they are also an avoidable cause of adverse drug reactions. The study of potential DDIs (pDDIs) would make it…
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Journal Article
Synthesis and Activity Test of 1-Allyl-3-(4-tertiary-Butylbenzoyl) Thioureaas a Candidate of an Analgesic Drug
Background: Urea derivatives showed good analgesic activity compared to diclofenac sodium. The addition of the allyl group to the thiourea and 4-tertiary-butylbenzoyl chlorideis expected to provide a better analgesic effect. Objective: The research aimed to synthesize…
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Journal Article
Acute and Subchronic Toxicity Assessment of 70% Ethanol Extract of Gendarusa Leaves In Vivo
Background: Justicia gendarussa Burm. f., has been used traditionally in Indonesia for antifertility. Nowadays, a capsule containing 70% ethanol extract of J. gendarussa leaves has been studied for safety. Objective: This study aimed to determine the acute and sub-chronic toxicity of 70% ethanol…
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Journal Article
Ethnomedicine Study on Justicia gendarussa for Male Contraception at the Nimboran Ethnic, Jayapura
Background: Justicia gendarussa from Papua has traditionally been used for the treatment of several diseases, and phytochemical studies have been carried out since 1987. Objective: This study aimed to determine the use of this plant as a male contraceptive that the Nimboran Ethnic and their…
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Journal Article
HPLC Method Optimization for Simultaneous Determination of Quercetin, Luteolin, Sinensetin, and Stigmasterol in Herbal Medicines
Background: Quercetin, luteolin, sinensetin and stigmasterol each is the main marker compound in extracts of Sonchus arvensis, Plantago major, Orthosiphon stamineus, and Strobilanthes crispus, respectively. These extracts show nephrolithiasis activity. For quality control of herbal medicines, a…
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Journal Article
Calcium Decay Ability of Extracts Chromolaena odorata L. Leaves (Asteraceae) on Kidney Stones
Background: Kidney stones are one of the causes of chronic and acute kidney failure symptoms. The flavonoid compounds in Chromolaena odorata leave extract are thought to dissolve calcium in kidney stones. Objective: This study aims to determine the activity of Chromolaena odorata leaves extract as…
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Journal Article
Analysis of Drug Use in Non-Ventilator Covid-19 Patients at Bangil Hospital
Background: Coronavirus Disease 2019 (Covid-19) is an infectious disease. Common signs and symptoms of Covid-19 infection include acute respiratory distress such as fever, cough and shortness of breath. Analysis of drug use in Non-Ventilator Covid-19 patients needs to be carried out to provide an…
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Journal Article
Assessing the Neurotoxicological Effect of the Acute Paraquat Aerosols Exposure in Causing Parkinsonism on Mouse through Behavioral Assays
Background: In the scientific community, there is no consensus that paraquat, a widely used herbicide, has a strong relationship with the occurrence of Parkinson's disease. A reliable epidemiological explanation of how paraquat can induce parkinsonism is urgently needed because it relates to the…
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Journal Article
Optimization Method and Stability Test to Determinate Luteolin, Quercetin, Apigenin, and Sinensetin Levels in Herbal Medicines Using TLC-Densitometry
Background: Nephrolithiasis is a condition in which there are one or more kidney stones in the pelvis or calyces. Luteolin, quercetin, apigenin, and sinensetin are marker compounds in the extracts of Plantago major, Sonchus arvensis, Strobilanthes crispus and Orthosiphon stamineus which have…
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Journal Article
Analysis of Antibiotic Use in COVID-19 Patients at a Hospital in Sidoarjo
Background: Antibiotics are given to COVID-19 patients to treat bacterial co-infections, but excessive and inappropriate antibiotic use can increase antibiotic resistance. Objective: The study aims to analyze the antibiotic use and bacterial susceptibility in COVID-19 patients at a hospital in…
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Journal Article
Mannitol Production from Fructose by Using Resting Cells of Methylotrophic Yeasts
Background: Mannitol is a polyol sugar widely used in pharmaceutical and food industries which can be produced by bioconversion. Using of resting cells and methanol as a carbon source are strategies to increase the efficiency of mannitol production by increasing NAD(P)H needed in the reduction…
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Journal Article
Assessment of Antibiotic Use in ICU Patients with Pneumonia Using ATC/DDD as a Quantitative Analysis Method
Background: Pneumonia is an infection of the lung tissue which is mainly caused by bacteria. High utilization and inappropriate use of antibiotics increase resistant bacteria, morbidity, mortality, and treatment cost. Quantitative evaluation becomes one of the indicators to assess the use of…
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Journal Article
Acute and Subchronic Toxicity of Indonesian House Dust Mites (IHDM) Allergenic Extract for Asthma Allergy Immunotherapy
Background: In developing a pharmaceutical product, it is necessary to conduct pre-clinical and clinical trials to ensure its safety and effectiveness. The toxicity test is conducted to assess the safety of a substance to determine its toxic effect of the substance. Objective: This study aims to…