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ISSN 2465-2628 · AboutScience Srl · 216 artikel di indeks
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Artikel Jurnal Teks lengkap
Erratum in: PedEoEvolution: optimizing pediatric and adolescent eosinophilic esophagitis management in Italy
Juga tersedia di: DOAJ
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Artikel Jurnal
A case of hydralazine-induced bullous pemphigoid
Introduction: Hydralazine-induced bullous pemphigoid (BP) is a rare adverse drug reaction where the medication may act to trigger an autoimmune response against proteins in the dermal-epidermal junction (DEJ). This case highlights the necessity of considering hydralazine as a potential cause of BP…
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Artikel Jurnal
Evidence-like error and physician responsibility in retrieval-augmented clinical artificial intelligence
Recent reports on the unavailability of OpenEvidence in the European Union and the United Kingdom have renewed debate on artificial intelligence, medicine, and regulation. This case has often been interpreted as further evidence of Europe’s structural difficulty in supporting technological…
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Artikel Jurnal
SyMMphony - From transplant-eligible newly diagnosed multiple myeloma to second-line CAR-T cell therapy: harmonizing treatment pathways to improve care
The management of transplant-eligible, newly diagnosed multiple myeloma is evolving with the adoption of anti CD38-based quadruplet regimens and the potential earlier use of anti-BCMA CAR T-cell therapy in lenalidomide refractory disease. In this context, the national macroregional syMMphony…
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Artikel Jurnal
Recombinant enzymes’ effect on scarring and fibrosis
Introduction: worldwide, a large number of surgical procedures are performed daily for aesthetic purposes, often providing excellent outcomes in terms of appearance enhancement. However, these interventions are not exempt from adverse effects, including visible skin alterations such as hypertrophic…
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Artikel Jurnal
Clinical artificial intelligence as a cognitive intervention: cognitive algovigilance, adverse events, and post-market surveillance
Artificial intelligence (AI) safety in medicine is still evaluated largely through model-centered metrics: accuracy, robustness, bias, drift, transparency, and regulatory compliance. These dimensions remain essential, but they do not capture the full safety problem created when AI enters clinical…
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Artikel Jurnal
Physiopathology of oxygen transport: the “Apple Ropeway” metaphor
Oxygen balance is fundamental to human life, requiring a delicate equilibrium between oxygen delivery (DO2) and consumption (VO2). While these physiological principles are critical for bedside clinicians, they are often perceived as complex, this article introduces a novel educational metaphor, the…
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Artikel Jurnal
Management of refractory metastatic colorectal cancer: consensus recommendations from Italian oncologists
Introduction: Metastatic colorectal cancer (mCRC) constitutes approximately 10% of all cancers globally and ranks as the second leading cause of cancer-related deaths. Management of refractory mCRC remains challenging due to pharmacological resistance and limited effective therapeutic options…
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Artikel Jurnal
Clinical and histological findings following the application of a single session of recombinant enzymes on the face
Introduction: Several factors influence the quality and appearance of the skin, including age, lifestyle, sun exposure, and certain conditions. These elements can have a significant negative impact on some individuals. As a result, esthetic medicine is increasingly sought after as a solution to…
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Artikel Jurnal
Effectiveness study of the recombinant enzymes pbserum HIGH in the treatment of pathological scars: a pilot study
Introduction: Pathological scars, despite the achievements of modern medicine, are still a problem. Its prevalence can reach up to 50% in emergency surgeries. These scars can lead to physical complications, including impaired mobility, altered sensation, and discoloration, and may even cause pain…
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Artikel Jurnal
Sharing Diagnostic and Therapeutic Pathways in Pulmonary Arterial Hypertension: A Roadmap for the Triveneto Region
Background: Pulmonary arterial hypertension (PAH) is a rare and progressive disease characterized by high mortality and a significant impact on quality of life. Despite therapeutic advances, considerable heterogeneity persists in Italy’s diagnostic and therapeutic pathways, leading to delays in…
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Artikel Jurnal
Evolution of Treatments for Hereditary Angioedema in Italy: Use of Lanadelumab in Clinical Practice
Introduction: Hereditary angioedema (HEA) is a rare genetic disorder characterised by recurrent episodes of edema affecting various body districts. HEA therapy includes treatment of acute attacks and short- or long-term prophylaxis. Objective: To describe the main demographic and clinical…
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Artikel Jurnal
From data to evidence: the evolving role of observational studies and target trial emulation in regulatory decision-making
Introduction: The European Medicines Agency (EMA) has updated its Reflection Paper on the use of Real-World Data (RWD) in Observational Studies (OS), emphasizing the regulatory importance of Real-World Evidence (RWE). Objectives: Summarize the main methodological recommendations of the EMA’s 2025…
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Artikel Jurnal
PedEoEvolution: optimizing pediatric and adolescent eosinophilic esophagitis management in Italy
This review addresses the unique challenges of pediatric eosinophilic esophagitis (EoE) management, aiming to develop a comprehensive knowledge base, standardize therapeutic approaches, and explore new targeted biological treatments. A non-systematic literature review was conducted, complemented by…
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Artikel Jurnal
Vitreoretinal interface disorders
This article is designed to bridge the knowledge gap for Doctors, shedding light on retinal pathologies that have long dwelled in the shadows of ultra-specialization. It delves into the identification and management of atypical conditions affecting the vitreomacular interface, encompassing…
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Artikel Jurnal
A case of exaggerated placental site treated with hysteroscopy
Exaggerated placental site (EPS) is a benign lesion that can occur in association with term pregnancy, ectopic pregnancy, molar pregnancy, intrauterine fetal death or miscarriage. The characteristics of EPS are described in several case reports and have been reported after major surgery such as…
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Artikel Jurnal
Hand hygiene for prevention and control of viral infections: the role of Amuchina Gel Xgerm [Accepted for publication]
Introduction: Alcohol-based hand sanitizers are used in healthcare settings, but their efficacy against both enveloped and non-enveloped viruses requires further investigation. Methods: In this study, viral suspensions composed by the test virus, an interfering substance, and the test product, were…